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Displaying drugs 701 - 725 of 1048 in total

Iopofosine I-124

Investigational
Matched Synonyms: … Ethanaminium, 2-((hydroxy((18-(4-(iodo-124i)phenyl)octadecyl)oxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride ... Qtern 5 mg/10 mg Film-Coated Tablets …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and dapagliflozin ... saxagliptin and dapagliflozin ... sitagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …
Matched Products: … FORXIGA 5MG FILM-COATED TABLET ... FORZIGA 10 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET IÇEREN 10'LÜK BLISTERLERDE ... FORZIGA 5 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET IÇEREN 10'LÜK BLISTERLERDE …

Nateglinide

Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Nateglinide is an amino acid derivative that induces an early insulin...
Approved
Investigational
Matched Description: … The major metabolites possess less activity than the parent compound. ... Nateglinide is extensively metabolized in the liver and excreted in urine (83%) and feces (10%). ... insulin and appears to occur only in those naïve to oral antidiabetic agents. …
Matched Mixtures name: … NAT-ALA 120/200 MG FILM KAPLI TABLET, 90 ADET ... NAT-ALA 180/200 MG FILM KAPLI TABLET, 90 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … NATALIX 120 MG FILM TABLET , FILM TABLET, 84 ADET ... NATALIX 180 MG FILM TABLET , FILM TABLET, 84 ADET ... INGLEX 180 MG FİLM TABLET, 84 ADET …

Minnelide

Investigational
Matched Synonyms: … 14-o-phosphonooxymethyltriptolide disodium salt ... 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium salt …

Otilonium

Experimental
Investigational
Matched Mixtures name: … SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 90 ADET ... DOLOSPAS 40 MG/80 MG FİLM KAPLI TABLET, 90 ADET ... SIMFLAT 40MG/80 MG FİLM KAPLI TABLET, 30 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents ... otilonium bromide and psycholeptics …
Matched Products: … EKSPAZ 40 MG FILM TABLET, 60 ADET ... EKSPAZ 40 MG FILM TABLET, 90 ADET ... PENSOTIL 40 MG FILM TABLET,90 ADET …

Riociguat

Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Description: … regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for ... Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO …
Matched Products: … Adempas 0.5mg film-coated tablet ... Adempas 1.5mg film-coated tablet ... Adempas 1mg film-coated tablet …

Pinaverium

Pinaverium is a spasmolytic agent used for functional gastrointestinal disorders. It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function. It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders and may be considered...
Approved
Matched Description: … It is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility ... disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium-Regulating Hormones and Agents …
Matched Products: … DICETEL 100MG FILM-COATED TABLET ... Dicetel 50mg Film-Coated Tablet ... PİNASPAZ 50 MG FİLM KAPLI TABLET, 40 ADET …

Ticagrelor

Ticagrelor, or AZD6140, was first described in the literature in 2003.[A204170,A2903] Ticagrelor is an ADP derivative developed for its P2Y12 receptor antagonism. Unlike clopidogrel, ticagrelor is not a prodrug. It is marketed by Astra Zeneca as Brilinta in the US and Brilique or Possia in the EU, . Ticagrelor was...
Approved
Matched Description: … [A2903] It is marketed by Astra Zeneca as Brilinta in the US[L14201] and Brilique or Possia in the EU …
Matched Categories: … Blood and Blood Forming Organs ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … BRILINTA 90MG FILM-COATED TABLET ... ABRİLOR 60 MG FİLM KAPLI TABLET, 56 ADET ... ALMINDA (FILM-COATED TABLETS 90 MG) …

Diltiazem

Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Description: … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. ... under various brand names with Cardizem and Tiazac being the most common ones. ... various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … PECTAZEM 60 MG KONTROLLÜ SALIM TABLET, 50 ADET …

Escitalopram

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety.[L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
Approved
Matched Description: … Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic [citalopram ... [A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. ... L8513,L8516,L8522] Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and …
Matched Products: … ANZYL 10 MG FILM TABLET ,56 FILM TABLET ... ANZYL 20 MG FILM TABLET ,56 FILM TABLET ... ANZYL 5 MG FILM TABLET ,FILM TABLET, 28 ADET …

Afatinib

Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Matched Description: … Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … GIOTRIF 20MG FILM-COATED TABLETS ... GIOTRIF 40MG FILM-COATED TABLETS ... GIOTRIF 30MG FILM-COATED TABLETS …

Tenofovir disoproxil

Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Mixtures name: … LAMIHOPE-T (LAMIVUDINE 300MG AND TENOFOVIR DISOPROXIL FUMARATE 300MG FILM-COATED TABLETS) ... FORSTAVIR-LE ( Efavirenz 600 mg, Lamivudine 300 mg and Tenofovir Disoproxil Fumarate 300 mg ) Film-coated ... TRUVADA 200 MG/245 MG FILM TABLET, 30 ADET …
Matched Categories: … Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and efavirenz ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Products: … TENVIR FILM-COATED TABLET ... VIRSOEM 245 MG FILM TABLET,30 ADET ... VIRSOEM 245 MG FILM TABLET, 90 ADET …

Cabozantinib

Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. It was initially approved in the US under the brand name Cometriq, which is indicated for the treatment of metastatic medullary thyroid cancer. In 2016, a capsule formulation (Cabometyx) was approved for the treatment of advanced renal...
Approved
Investigational
Matched Description: … Cabozantinib was first approved in 2012 and is a non-specific tyrosine kinase inhibitor. ... a capsule formulation (Cabometyx) was approved for the treatment of advanced renal cell carcinoma, and ... this same formulation gained additional approval in both the US and Canada in 2019 for the treatment …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … CABOMETYX 40mg film-coated tablets ... CABOMETYX 20mg film-coated tablets ... CABOMETYX FILM COATED TABLET 20MG …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Description: … thrombocytopenia (low blood platelet counts) in patients with chronic hepatitis C to allow them to initiate and …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … REVOLADE FILM-COATED TABLET 25MG ... REVOLADE FILM-COATED TABLET 50MG ... REVOLADE 12.5 MG FİLM TABLET, 14 ADET …

Maraviroc

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. It was originally labelled as UK-427857 during development but was assigned the Maraviroc name...
Approved
Investigational
Matched Description: … company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and …
Matched Products: … Celsentri Film-Coated Tablet 300mg ... Celsentri Film-Coated Tablet 150mg ... CELSENTRI 150 MG FILM KAPLI TABLET ,180 ADET …

Idebenone

Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC). It has been proposed that by interacting with the ETC, idebenone increases ATP production required for mitochondrial function, reduces free radicals, inhibits lipid peroxidation, and...
Approved
Investigational
Matched Description: … Idebenone is a synthetic analogue of ubiquinone (also known as Coenzyme Q10), a vital cell antioxidant and ... consequently protects the lipid membrane and mitochondria from oxidative damage [A19768]. ... for its potential use in Alzheimer's Disease and other cognitivie disorders [A19769]. …
Matched Mixtures name: … BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 28 ADET ... BERMAXIN 90/10/5 MG FILM TABLET ,FILM TABLET, 84 ADET ... EVERON 90/5 MG FILM KAPLI TABLET ,50 TABLET …
Matched Categories: … Enzymes and Coenzymes ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … IDEBEX 45 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 90 MG FILM KAPLI TABLET ,90 FILM KAPLI TABLET ... IDEBEX 45 MG FILM KAPLI TABLET ,FILM KAPLI TABLET, 30 ADET …

Leflunomide

Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and ... Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Leflunomide and metabolite …
Matched Products: … ARAMID 10 MG FILM TABLET ,FILM TABLET, 30 ADET ... ARAMID 20 MG FILM TABLET ,FILM TABLET, 30 ADET ... ARAMID 100 MG FİLM TABLET, 3 ADET …

Macitentan

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Description: … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October …
Matched Categories: … macitentan and tadalafil …
Matched Products: … OPSUMIT FILM-COATED TABLET 10MG ... Opsumit ® 10mg Film-Coated Tablets ... Opsumit 10mg Film-Coated Tablets …

Spiramycin

Spiramycin is a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and rods, Gram-negative cocci and also Legionellae, mycoplasmas, chlamydiae, some types of spirochetes, Toxoplasma gondii and Cryptosporidium. Spiramycin is a 16-membered ring macrolide discovered in 1952 as a product of Streptomyces ambofaciens that has been available in...
Approved
Matched Description: … Toxoplasma gondii and Cryptosporidium. ... a primarily bacteriostatic macrolide antimicrobial agent with activity against Gram-positive cocci and ... Resistant organisms include Enterobacteria, pseudomonads, and moulds. …
Matched Mixtures name: … METİRASİN 1,5 MIU/250 MG FILM TABLET, 10 ADET ... METİRASİN 1,5 MIU/250 MG FILM TABLET, 14 ADET …
Matched Categories: … spiramycin and metronidazole ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … FİLM KAPLI TABLET , 10 ADET ... FİLM KAPLI TABLET , 14 ADET ... SPRAMAX 1,5 MIU FİLM KAPLI TABLET, 10 ADET …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Description: … for patients with metastatic bladder cancer, which demonstrates the development of more personalized and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … BALVERSA FILM-COATED TABLETS 3MG ... BALVERSA FILM-COATED TABLETS 5MG ... BALVERSA FILM-COATED TABLETS 4MG …

Clopidogrel

Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral...
Approved
Matched Description: … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and ... with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and ... be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and …
Matched Mixtures name: … CoPlavix Film-Coated Tablet 75 mg/100 mg ... CoPlavix 75/100mg Film-Coated Tablet …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Plavix Film-Coated Tablet 300 mg ... MYOCLIP FILM COATED TABLET 75MG ... PLATEL FILM COATED TABLETS 75MG …

Ambrisentan

Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. ... ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise …
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … VOLIBRIS 10 MG FILM COATED TABLET ... VOLIBRIS FILM-COATED TABLET 5MG ... VOLIBRIS FILM-COATED TABLET 10 MG …

Favipiravir

Discovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza.[A191688,A191721] The antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and replication of viral genomes.[A191688,A191772,A191775] Not only does favipiravir inhibit...
Approved
Investigational
Matched Description: … antiviral targets RNA-dependent RNA polymerase (RdRp) enzymes, which are necessary for the transcription and ... [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but ... the drug has shown promise in the treatment of avian influenza, and may be an alternative option for …
Matched Products: … AVIGAN Film-Coated Tablets 200mg (Favipiravir) ... KOVİPİR 200 MG FİLM KAPLI TABLET, 40 ADET ... FAVİRA 200 MG FİLM KAPLI TABLET, 40 ADET …

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Description: … INR testing, and numerous drug-drug and drug-food interactions. ... atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism ... Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … LIXIANA FILM-COATED TABLET 30 MG ... LIXIANA FILM-COATED TABLET 60 MG ... LIXIANA FILM-COATED TABLET 15 MG …

Pirfenidone

Pirfenidone is a synthetic pyridone drug. It is an antifibrotic agent with anti-inflammatory and antioxidant properties that is used to treat idiopathic pulmonary fibrosis (IPF), which is a chronic, progressive form of interstitial pneumonia. While its mechanism of action is not yet fully understood, pirfenidone is proposed to primarily regulate...
Approved
Investigational
Matched Description: … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that ... fully understood, pirfenidone is proposed to primarily regulate tumor necrosis factor (TNF) pathways and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ESBRIET FILM COATED TABLET 267MG ... ESBRIET FILM COATED TABLET 801MG ... ESBRIET (FILM-COATED TABLETS 267 MG) …
Displaying drugs 701 - 725 of 1048 in total