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Displaying drugs 701 - 725 of 3101 in total
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … D-Cystein ... D-Amino-3-mercaptopropionic acid ... (2S)-2-amino-3-mercaptopropanoic acid
Matched Name: … D-Cysteine
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid
Matched Description: … A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. …
Matched Salts name: … D-Cysteine hydrochloride monohydrate …
Experimental
Matched Name: … Tosyl-D-Proline
Matched Iupac: … (2R)-1-(4-methylbenzenesulfonyl)pyrrolidine-2-carboxylic acid
Experimental
Matched Synonyms: … Proline betaine ... N,N-dimethyl-L-proline
Matched Name: … L-proline betaine …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Investigational
Matched Synonyms: … Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15 …
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Pegylated proline interferon alpha-2b ... Pegylated proline-interferon alpha-2b …
Matched Description: … A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α ... platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term ... propensity for myelofibrosis and leukemia. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and ... (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Categories: … Acid Sensing Ion Channel Blockers …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours. It is being investigated in other cancers.
Approved
Investigational
Matched Synonyms: … Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus …
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … STERILE PREDNISOLONE ACETATE SUSPENSION ... PREDNISOLON ACIS 5MG ... PREDNISOLON ACIS 10MG …
Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
Investigational
Matched Synonyms: … 1-methyl-D-tryptophan ... (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Matched Iupac: … (2R)-2-amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Matched Description: … Indoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Tryptophan Oxygenase, antagonists & inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Synonyms: … Gadobenic acid ... Acide gadobenique ... Acido gadobenico …
Matched Name: … Gadobenic acid
Matched Description: … other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based …
Matched Categories: … gadobenic acid
Experimental
Matched Synonyms: … 2-D-Methyl-3-mercaptopropanoyl-L-proline ... (2S)-1-((2R)-2-Methyl-3-sulfanylpropanoyl)pyrrolidine-2-carboxylic acid
Matched Iupac: … (2S)-1-[(2R)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … 3R,5R)-5-(4-AMINO-2-OXO-PYRIMIDIN-1-YL)-4,4-DIFLUORO-3-HYDROXY-TETRAHYDROFURAN-2-YL)METHOXY-PHENOXY-PHOSPHORYL ... L-ALANINE, N-(2'-DEOXY-2',2'-DIFLUORO-P-PHENYL-5'-CYTIDYLYL)-, PHENYLMETHYL ESTER ... N-[[P(S)]-2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl]-L-alanine phenylmethyl ester …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Investigational
Matched Synonyms: … L-arginine, l-leucyl-l-prolyl-l-prolyl-l-seryl- ... L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine
Matched Name: … L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate
Matched Salts name: … Norethisterone acetate
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Genito Urinary System and Sex Hormones ... norethisterone and estrogen …
Matched Products: … Norethindrone Acetate ... Norethindrone acetate
Experimental
Matched Synonyms: … Quingestanol acetate ... Norethindrone acetate 3-cyclopentyl enol ether …
Matched Name: … Quingestanol acetate
Matched Iupac: … )-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Vet approved
Matched Synonyms: … Copper glycinate ... Cupric glycinate ... Copper(II) glycinate
Matched Name: … Cupric glycinate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental
Matched Synonyms: … beta-(2,4-Dihydroxypyrimidin-1-yl)alanine
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G2 (224-ARGININE,265-ALANINE,330-SERINE,331-SERINE), ANTI-(HUMAN CD3 ANTIGEN .EPSILON. …
Matched Description: … ), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of which contributes one heavy chain and one light ... It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Miridesap has been used in trials studying the prevention of HIV and treatment of AL amyloidosis.
Investigational
Matched Synonyms: … 1,1'-hexanedioyldi-D-proline
Matched Iupac: … (2R)-1-{6-[(2R)-2-carboxypyrrolidin-1-yl]-6-oxohexanoyl}pyrrolidine-2-carboxylic acid
Matched Description: … Miridesap has been used in trials studying the prevention of HIV and treatment of AL amyloidosis. …
Illicit
Matched Synonyms: … dl-alpha-prodine
Experimental
Matched Synonyms: … -alanine, n-((2r)-2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonooxy)butyl)- ... 4'-phosphopantothenic acid ... 4'-phospho-d-pantothenic acid
Matched Name: … Phosphopantothenic acid
Matched Iupac: … 3-[(2R)-2-hydroxy-3-methyl-3-[(phosphonooxy)methyl]butanamido]propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alanine ... Amino Acids
Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).
Investigational
Matched Synonyms: … Phorbol myristate acetate ... Tetradecanoylphorbol acetate ... Phorbol 12-myristate 13-acetate
Matched Name: … Phorbol 12-myristate 13-acetate diester …
Matched Description: … Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs). …
Experimental
Matched Name: … O-Benzylsulfonyl-Serine
Matched Iupac: … (2S)-2-amino-3-(phenylmethanesulfonyloxy)propanoic acid
Experimental
Matched Name: … N-Acetyl-Serine
Matched Iupac: … (2S)-2-acetamido-3-hydroxypropanoic acid
Experimental
Matched Name: … N-Dimethyl-Lysine
Matched Iupac: … (2S)-2-amino-6-(dimethylamino)hexanoic acid
Displaying drugs 701 - 725 of 3101 in total