Displaying drugs 51 - 75 of 691 in total
Goflikicept
Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-cov-2) Infection (COVID-19)).
Investigational
Matched Synonyms: … a mutant Fc fragment of human IGg1 and part of human IL1 receptor accessory protein ... Heterodimeric fusion protein that binds to IL-1 beta consisting of human extracellular domain of IL1 receptor and …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
Matched Description: … Goflikicept is under investigation in clinical trial NCT04380519 (Study of the Efficacy and Safety of ... a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe …
Reteplase
Human tissue plasminogen activator, purified, glycosylated, 355 residues purified from CHO cells. Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA. Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. Retavase...
Approved
Investigational
Matched Synonyms: … Human t-PA (residues 1-3 and 176-527) …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Matched Description: … Retavase contains 355 of the 527 amino acids of native human tPA (amino acids 1-3 and 176-527), and retains ... the activity-related kringle-2 and serine protease domains of human tPA. ... Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes ... Blood and Blood Forming Organs …
Colestipol
Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Synonyms: … Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxirane …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Categories: … Medications that reduce magnesium levels …
Matched Description: … enhanced secretion of bile acids and lipids in the feces, patients who take complicated medication regimens ... [FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated ... cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia …
Matched Categories: … Medications that reduce magnesium levels …
Antihemophilic factor (recombinant), PEGylated
Antihemophilic Factor (Recombinant), PEGylated, was approved by the FDA in December 2016 as the product Adynovate [FDA label].
Antihemophilic Factor (Recombinant), PEGylated, is a recombinant full-length human coagulation factor VIII (2,332 amino acids with a molecular weight (MW) of approximately 280 kDa) covalently conjugated with at least one molecule of...
Approved
Investigational
Matched Description: … It has been created to increase the half-life of factor VIII, which decreases dose frequency and decreases ... PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … ADYNOVATE 3000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 250 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... ADYNOVATE 1000 IU POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …
Egg yolk
Egg yolk allergenic extract is used in allergenic testing.
Approved
Matched Products: … Food - Animal Products and Poultry Products, Egg, Yolk Gallus sp. …
VOR33
VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Matched Description: … VOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy …
Chloroxylenol
Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Description: … disinfection and surgical instruments. ... Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin ... It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … HACCP Flat Top E-2 ... Uscalrite Tec E-1 - Liq Top 0.5% ... Spartan E2 Hand Wash and Sanitizer …
Matched Categories: … Antiseptics and Disinfectants ... Phenol and Derivatives …
Matched Products: … HACCP Flat Top E-2 ... Uscalrite Tec E-1 - Liq Top 0.5% ... Spartan E2 Hand Wash and Sanitizer …
Egg white
Egg white allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Gallus gallus egg white …
Matched Products: … Food - Animal Products and Poultry Products, Egg, White Gallus sp. …
Matched Products: … Food - Animal Products and Poultry Products, Egg, White Gallus sp. …
Moroctocog alfa
Moroctocog alfa, also known as BDDrFVIII (B domain deleted recombinant factor VIII), is a recombinant DNA-based drug with functional characteristics comparable to those of endogenous coagulation Factor VIII, the essential human blood clotting protein that is impaired in Hemophilia A. Moroctocog alfa is identical in sequence to endogenously produced Factor...
Approved
Matched Description: … purified Factor VIII from human pooled blood and contains both A- and B-subunits, and [DB11607], which ... Moroctocog alfa is approved by Health Canada and by the European Medicines Agency for the control and ... prevention of hemorrhagic episodes and for routine and surgical prophylaxis in patients with hemophilia …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Xyntha 250 IU Powder and Solvent for Solution for Injection ... Xyntha 1000 IU Powder and Solvent for Solution for Injection ... Xyntha 500 IU Powder and Solvent for Solution for Injection …
Smallpox and Monkeypox Vaccine, Live, Non-replicating
Approved
Matched Name: … Smallpox and Monkeypox Vaccine, Live, Non-replicating …
Pasireotide
Pasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Approved
Matched Iupac: … hexaoxo-3-phenyl-icosahydropyrrolo[1,2-a]1,4,7,10,13,16-hexaazacyclooctadecan-19-yl N-(2-aminoethyl)carbamate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Somatostatin and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … SIGNIFOR LAR(60 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) ... SIGNIFOR LAR (40 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION) …
DCVAC/OvCa
DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo. It is under investigation for the treatment of ovarian cancer.
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with killed ovarian cancer cells and matured by TLR3 ligand ex vivo …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
Matched Description: … DCVAC/OvCa is a therapy comprising autologous dendritic cells pulsed with killed ovarian cancer cells and …
CHF5633
CHF5633 is a fully synthetic pulmonary surfactant preparation comprising DPPC (dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and a synthetic SP-B analogue.
Investigational
Matched Synonyms: … Synthetic surfactant comprised of DPPC, POPG Na, synthetic SP-C analogue and synthetic SP-B analogue …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … dipalmitoylphosphatidylcholine), POPG Na (palmitoyl‐oleoyl‐phosphatidylglycerol sodium), a synthetic SP-C analogue, and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Anbenitamab
Investigational
Matched Synonyms: … FC-fusion bispecific antibody targeting extracellular domains II and IV of HER 2 and FC-fusion bispecific ... IgG1 antibody inhibiting PD-L1 and CTLA-4 …
Pyrithione
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Description: … and seborrheic dermatitis. ... by fungi such as _Malassezia globosa_ and _M. restricta_ [A32162]. ... of proteins essential for fungal metabolism and growth [A27132]. …
Matched Mixtures name: … Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Smooth and Silky …
Matched Categories: … Gallium Radioisotopes …
Matched Products: … Head and Shoulders smooth and silky ... Head and Shoulders Smooth and Silky ... Dandruff Shampoo and Conditioner With Cucumber and Lemongrass Extracts …
Matched Mixtures name: … Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Full and Strong ... Head and Shoulders Dual Sachets Smooth and Silky …
Matched Categories: … Gallium Radioisotopes …
Matched Products: … Head and Shoulders smooth and silky ... Head and Shoulders Smooth and Silky ... Dandruff Shampoo and Conditioner With Cucumber and Lemongrass Extracts …
CVac
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
AMG 424
AMG 424 is a novel, humanized, anti-CD3/CD38 bispecific monoclonal antibody being investigated for multiple myeloma.
Investigational
Matched Synonyms: … Humanized Bi-Specific Xmab(R) T Cell Recruiting Antibody Construct Directed Against Cd3 And Cd38 …
NTLA-2002
NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9. It is an investigational therapy designed to knock out the target gene kallikrein B1 (KLKB1) to reduce plasma kallikrein activity, thereby preventing hereditary angioedema attacks.
Investigational
Matched Synonyms: … lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …
Matched Description: … 2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and …
Linvoseltamab
Linvoseltamab is an investigational bispecific antibody. It promotes the interaction of B-cell maturation antigen (BCMA) on multiple myeloma cells with CD3-expressing T cells.
Investigational
Matched Synonyms: … human IgG4-based anti-CD3 x anti-BCMA bispecific monoclonal antibody that binds to CD3 and BCMA …
GTP-506
GTP-506 is a gene therapy formed by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and a therapeutic donor vector that inserts the OTC gene to provide the desired genetic correction.
Investigational
Matched Synonyms: … Non-replicating recombinant adeno-associated virus serotype rh79 (AAVrh.79) vectors: AAVrh79.TBG.M2PCSK9.WPRE.bGH and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …
Matched Description: … by two vectors, a nuclease vector targeting gene editing in the well-characterized PCSK9 gene locus and …
Degarelix
Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH. This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately causes testosterone suppression. Reduction in...
Approved
Matched Description: … derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and ... This antagonism reduces luteinising hormone (LH) and follicle-stimulating hormone (FSH) which ultimately …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … Firmagon 120mg Powder and Solvent for Solution for Injection ... Firmagon 80mg Powder and Solvent for Solution for Injection ... FIRMAGON Powder and Solvent for Solution for Injection 120 mg …
Sarocladium strictum
Sarocladium strictum allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, acremonium strictum ... Molds, rusts and smuts, cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Matched Products: … Molds, Rusts and Smuts, Cephalosporium acremonium …
Lonoctocog alfa
Approved
Investigational
Matched Products: … AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 250IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500IU/VIAL ... AFSTYLA POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 1000IU/VIAL …
ARGX-119
ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK).
Investigational
Matched Synonyms: … humanized immunoglobulin gamma 1 (IgG1) agonistic monoclonal antibody (mAb) that specifically targets and …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Matched Description: … ARGX-119 is a monoclonal antibody that targets and activates muscle-specific kinase (MuSK). …
Esomeprazole
Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Salts name: … Esomeprazole magnesium ... Esomeprazole magnesium dihydrate ... Esomeprazole magnesium trihydrate …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Omeprazole and enantiomer ... naproxen and esomeprazole …
Matched Products: … Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment ... Foster and Thrive Acid Reducer …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Salts name: … Esomeprazole magnesium ... Esomeprazole magnesium dihydrate ... Esomeprazole magnesium trihydrate …
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Omeprazole and enantiomer ... naproxen and esomeprazole …
Matched Products: … Up and Up Esomeprazole Magnesium ... Berkley and Jensen Heartburn Treatment ... Foster and Thrive Acid Reducer …
Displaying drugs 51 - 75 of 691 in total