Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Did you mean category antidepressive agent an group approved?
Displaying drugs 51 - 75 of 10312 in total

Danazol

A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders.
Approved
Matched Description: … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary …
Matched Categories: … Antigonadotropins and Similar Agents ... Hyperglycemia-Associated Agents …

Activated charcoal

Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Description: … Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion ... It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network …
Matched Categories: … Antifoaming Agents ... Protective Agents ... Antidiarrheals, Intestinal Antiinflammatory/antiinfective Agents …

Pipotiazine

Pipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extra pyramidal reactions. It is...
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Antipsychotic Agents ... Serotonin Agents ... Neurotoxic agents ... Photosensitizing Agents …

Calcium levulinate

The relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide . The resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in...
Approved
Experimental

Thiothixene

A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Approved
Matched Description: … A thioxanthine used as an antipsychotic agent. …
Matched Categories: … Antidepressive Agents ... Antipsychotic Agents ... Dopamine Agents ... Serotonin Agents ... Neurotoxic agents …

Lenacapavir

HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Description: … HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly ... inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral agents ... [L42995] On December 22, 2022, it was also approved by the FDA.[L44473] …
Matched Categories: … Anti-HIV Agents ... Antiviral Agents …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Description: … [L50592] This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984. ... Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the ... [A176471] Even though hydromorphone does not present a 6-hydroxyl group, it is categorized under the …
Matched Categories: … Central Nervous System Agents ... Sensory System Agents ... Peripheral Nervous System Agents …

Mebeverine

Mebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Approved
Investigational
Matched Categories: … Synthetic Anticholinergics, Esters With Tertiary Amino Group ... Autonomic Agents ... Anticholinergic Agents ... Agents producing tachycardia ... Agents Causing Muscle Toxicity …

Glasdegib

Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group of benzimidazoles. In early research, benzimidazoles attracted large interest as they represented a class of inhibitors with low molecular weight, potent inhibitory activity, and lacking unstable functionality. The great lipophilicity of this group of compounds...
Approved
Investigational
Matched Description: … [A40310] Glasdegib was developed by Pfizer Inc and approved on November 21, 2018 by the FDA for the ... Currently, the current gold standard of AML in older patients is still venetoclax with hypomethylation agents ... Glasdegib, also known as PF-04449913, is a small-molecule hedgehog signaling inhibitor selected under the group …
Matched Categories: … Antineoplastic Agents ... QTc Prolonging Agents ... Highest Risk QTc-Prolonging Agents ... Antineoplastic and Immunomodulating Agents …

Titanium dioxide

Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Mixtures name: … Seoyoon Hanbang Ja An Cover BB Cream …
Matched Categories: … Coloring Agents ... Sunscreen Agents ... Protective Agents ... Photosensitizing Agents ... Radiation-Protective Agents …
Matched Products: … An Adc Whitening Bb ... An Adc Sp Intensive Bb …

Amoxicillin

Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Mixtures name: … Truemed Group LLC ... AMOXICILLINA E ACIDO CLAVULANICO TEVA GROUP ... AMOXICILLINA E ACIDO CLAVULANICO TEVA GROUP …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Description: … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. ... efficacious in reducing blood pressure when used alone or in conjunction with other antihypertensive agents …
Matched Categories: … Hypotensive Agents ... Antihypertensive Agents ... Agents causing hyperkalemia ... Agents Acting on the Renin-Angiotensin System ... Antihypertensive Agents Indicated for Hypertension …

Medifoxamine

Medifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, and Morrocco in the 1990s but was later withdrawn from the market due to it causing cases of hepatotoxicity [L5461, A174976].
Approved
Matched Description: … Medifoxamine was marketed as an atypical antidepressant, with anxiolyitc properties in France, Spain, …
Matched Categories: … Antidepressive Agents …

Amiodarone

Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings. Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. Because of its ability to cause serious toxicity and possibly death, amiodarone...
Approved
Investigational
Matched Description: … [A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also ... its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved …
Matched Categories: … Antiarrhythmic agents ... Agents causing hyperkalemia ... Cardiovascular Agents ... Hypotensive Agents ... Vasodilating Agents …

Amitriptylinoxide

Amitriptylinoxide has been used in trials studying Major Depression.
Approved
Investigational
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Tricyclic ... Neurotoxic agents ... Agents that produce hypertension ... Agents that reduce seizure threshold …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … or other oral hypoglycemic agents. ... [A6757] Dapagliflozin has been investigated either as monotherapy or as an adjunct treatment with insulin ... [A261601] Dapagliflozin was originally approved by the FDA on Jan 08, 2014, to improve glycemic control …
Matched Categories: … Hypotensive Agents ... Blood Glucose Lowering Agents …

Sonidegib

Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer agent by Novartis. It was FDA approved in 2015 for the treatment of basal cell carcinoma.
Approved
Investigational
Matched Description: … It was FDA approved in 2015 for the treatment of basal cell carcinoma. ... Sonidegib is a Hedgehog signaling pathway inhibitor (via smoothened antagonism) developed as an anticancer …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Pentetic acid

Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Description: … DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. ... [A32501] It is currently considered, in all the dosage forms, as a member of the list of approved inactive …
Matched Categories: … Chelating Agents ... Protective Agents ... Sequestering Agents ... Iron Chelating Agents …

Voxilaprevir

Voxilaprevir is a Direct-Acting Antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Investigational
Matched Description: … an HCV regimen containing sofosbuvir without an NS5A inhibitor [L935]. ... Vosevi is approved for the treatment of adult patients with chronic HCV infection with genotype 1, 2, ... Prior to Vosevi, there were no approved retreatment options for patients who have previously received …
Matched Categories: … Antiviral Agents …

Tozinameran

The Pfizer-BioNTech COVID-19 vaccine (also known as BNT162b2, Tozinameran, and Comirnaty), is one of four advanced mRNA-based vaccines developed through "Project Lightspeed," a joint program between Pfizer and BioNTech.[L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized full-length version of the severe acute respiratory syndrome coronavirus 2...
Approved
Investigational
Matched Description: … [L15002,L15007,L36025] Comirnaty is a nucleoside modified mRNA (modRNA) vaccine encoding an optimized ... Comirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older. ... [L26966,L26976] In November 2021, Health Canada [L39115] and the EMA [L39272] approved the vaccine to …

Gadofosveset trisodium

Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA), which is a non-invasive way of imaging blood vessels. The agent allows for the vascular system to be imaged more clearly by the MRA. In this way, gadofosveset trisodium is used to help diagnose certain disorders of the...
Approved
Matched Description: … Gadofosveset trisodium is an intravenous contrast agent used with magnetic resonance angiography(MRA) …

N-alkyl ethylbenzyl dimethyl ammonium (C12-C14)

N-alkyl ethylbenzyl dimethyl ammonium (c12-c14) is a quaternary ammonium compound with surfactant properties. It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties. Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive and gram-negative antibacterial activities...
Approved
Matched Description: … Employed in a great variety of cleaning agents and sanitizing agents, it possesses relatively broad gram-positive ... It is found in sanitizing solutions or soaps as an active ingredient due to its antimicrobial properties …

Fomivirsen

Fomivirsen is a antisense 21 mer phosphorothioate oligonucleotide. It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised patients, including those with AIDS. As a complementary nucleotide to the messenger RNA of the major immediate-early region proteins of human cytomegalovirus, it disrupts the...
Approved
Investigational
Withdrawn
Matched Description: … marketed under the trade name Vitravene for intravitreal injection and was the first antisense drug to be approved ... It is an antiviral agent that was used in the treatment of cytomegalovirus retinitis (CMV) in immunocompromised ... immediate-early region proteins of human cytomegalovirus, it disrupts the replication of the virus through an …
Matched Categories: … Antiviral Agents ... Anti-Infective Agents …

Vestronidase alfa

Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Description: … Vestronidase alfa was FDA-approved on November 17th, 2017 under the trade name Mepsevii as an intravenous ... Vestronidase alfa is an enzyme replacement therapy for the treatment of mucopolysaccharidosis type VII ... (MPS VII), also known as Sly syndrome, which is an inherited, rare genetic metabolic condition that …
Displaying drugs 51 - 75 of 10312 in total