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Displaying drugs 726 - 750 of 1155 in total
Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase, and several protease inhibitors . It works by selectively inhibiting the biosynthesis of proinflammatory prostaglandins and also has analgesic properties,...
Investigational
Matched Synonyms: … Bromelain protease ... Pineapple protease
Matched Description: … , escharase, and several protease inhibitors [A27198]. ... different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase ... has analgesic properties, as well as anticancerous and pro-apoptotic effects. …
Matched Mixtures name: … Bromelain and Papain Tab ... Pancreatin and Enzyme Formula - Tablet …
Matched Categories: … Enzymes and Coenzymes ... Preparations for Treatment of Wounds and Ulcers …
Velafermin was a novel investigational protein therapeutic, also known as fibroblast growth factor-20 (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated activity in multiple animal models. Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis by fostering the...
Investigational
Matched Synonyms: … RECOMBINANT HUMAN FIBROBLAST GROWTH FACTOR-20 ... FIBROBLAST GROWTH FACTOR 20 (HUMAN RECOMBINANT CG53135) …
Matched Description: … (FGF-20), which promotes both epithelial and mesenchymal cell proliferation in vitro and has demonstrated ... by fostering the regeneration and repair of the cells lining the gastrointestinal tract. ... Velafermin was investigated as a potential therapy for the prevention and treatment of oral mucositis …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Proteins
Lecanemab is a recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and insoluble forms of amyloid beta (Aβ), which are implicated in the pathophysiology of Alzheimer’s disease. Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952] with high selectivity to Aβ...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human beta-amyloid protofibril) (human-mus musculus monoclonal BAN2401 heavy ... chain), disulfide with human-mus musculus monoclonal BAN2401 light chain, dimer …
Matched Description: … recombinant humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody directed against aggregated soluble and ... [L44537] Lecanemab works to reduce Aβ plaques and prevent Aβ deposition in the brain [A253947,A253952 …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … (human-mus musculus monoclonal m9346a heavy chain), disulfide with human-mus musculus monoclonal m9346a ... Immunoglobulin g1, anti-(human folate receptor .alpha.) …
Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab (GSK3511294) in Participants With Chronic Rhinosinusitis With Nasal Polyps).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain ... ), disulfide with human-mus musculus monoclonal gsk3511294 .kappa. …
Matched Description: … Depemokimab is under investigation in clinical trial NCT05274750 (Efficacy and Safety of Depemokimab …
Metelimumab (CAT-192) is a monoclonal antibody targeted against transforming growth factor (TGF) beta-1.
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human transforming growth factor .beta.1 (human monoclonal cat-192 .gamma.4- ... chain)), disulfide with human monoclonal cat-192 .kappa. ... Human anti-transforming growth factor beta 1 monoclonal antibody …
Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab in Patients With Neuromyelitis Optica Spectrum Disorders (AQUARELLE)).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd20 antigen) (human-mus musculus monoclonal bcd-132 .gamma.1-chain), ... disulfide with human-mus musculus monoclonal bcd-132 .kappa. …
Matched Description: … Divozilimab is under investigation in clinical trial NCT05730699 (Efficacy and Safety of Divozilimab …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Proteins ... Blood Proteins
Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Investigational
Matched Synonyms: … Recombinant human gelsolin …
Matched Name: … Recombinant human plasma gelsolin …
Matched Description: … Plasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intracellular Signaling Peptides and Proteins ... Proteins ... Carrier Proteins ... Cytoskeletal Proteins
Experimental
Matched Synonyms: … Protein hydrolyzates, soya ... Hydrolyzed soy protein (enzymatic; 2000 mw) …
Matched Name: … Hydrolyzed soy protein
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Synonyms: … Coagulation factor X (human) ... Human coagulation factor X …
Matched Name: … Coagulation factor X human
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... children (aged 12 years and above) with hereditary Factor X deficiency. ... the perioperative setting for the management of bleeding in major surgery in patients with moderate and
Matched Mixtures name: … OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION ... OCTAPLEX POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 500 IU …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes ... Proteins ... Blood Proteins
Investigational
Matched Synonyms: … Human IL-15 …
Matched Name: … Interleukin-15, human recombinant …
Investigational
Matched Name: … Recombinant Factor XIII (human) …
Investigational
Matched Synonyms: … Recombinant soluble CD4 (human) …
Matched Name: … Recombinant soluble human CD4 …
Investigational
Matched Name: … Human glial progenitor cells …
Amniotic epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human amnion, the layer of the placenta closest to the fetus.[A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine due to their potential for differentiation and multiplication.
Investigational
Matched Synonyms: … Human Amniotic Epithelial Cells …
Matched Description: … due to their potential for differentiation and multiplication. ... [A220183,T823] These cells are potential candidates for allogeneic cell therapy and regenerative medicine ... epithelial cells (AEC) are multipotent stem-like cells derived from the basement collagenous membrane of the human
Investigational
Matched Synonyms: … Recombinant human biglycan …
CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.
Investigational
Matched Synonyms: … fibrinogen-depleted human platelet lysate …
Matched Description: … CAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen. …
Investigational
Matched Synonyms: … with human monoclonal gc1102 .kappa. ... Recombinant hepatitis B human immunoglobulin ... Hepatitis B virus neutralizing human monoclonal antibody …
Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47. It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome).
Investigational
Matched Synonyms: … Immunoglobulin g4 (225-proline), anti-(human cd47 antigen) (human-mus musculus monoclonal ak117 .gamma ... .4-chain), disulfide with human-mus musculus monoclonal ak117 .kappa. …
Andecaliximab is a monoclonal antibody directed against matrix metallopeptidase 9 (MMP9). Andecaliximab is under investigation in clinical trial NCT03631836 (Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g4, anti-(human gelatinase b) (human-mus musculus monoclonal gs-5745 heavy chain), disulfide ... with human-mus musculus monoclonal gs-5745 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Briquilimab is a humanized aglycosylated IgG1 kappa monoclonal antibody targeting CD117 (cKit).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1 (297-GLUTAMINE), ANTI-(HUMAN C-KIT RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL JSP191 ... .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL JSP191 .KAPPA. …
Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and Safety of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And/or Chronic Cutaneous Lupus Erythematosus (CCLE) With or Without Systemic Manifestations and Refractory And/or Intolerant to Antimalarial Therapy).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human blood dendritic cell antigen 2) (human-mus musculus monoclonal biib059 ... .gamma.1-chain), disulfide with human-mus musculus monoclonal biib059 .kappa. …
Matched Description: … Litifilimab is under investigation in clinical trial NCT05531565 (A Study to Assess the Efficacy and ... And/or Intolerant to Antimalarial Therapy). ... of BIIB059 (Litifilimab) in Participants With Active Subacute Cutaneous Lupus Erythematosus (SCLE) And
Olinvacimab is under investigation in clinical trial NCT03033524 (Trial to Evaluate the Safety of Ttac-0001(tanibirumab) in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ttac- ... Fully human monoclonal antibody targets vascular endothelial growth factor receptor 2 ... 0001 heavy chain), disulfide with human monoclonal ttac-0001 light chain, dimer …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Proteins ... Blood Proteins
Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/factor VIIa complex with novel antithrombotic activity.
Investigational
Matched Synonyms: … Recombinant nematode anticoagulant protein c2 ... Recombinant nematode anticoagulant protein-2 ... recombinant nematode anticoagulant protein c2 (rNAPc2) …
Matched Description: … Recombinant nematode anticoagulant protein c2 (rNAPc2) is a specific inhibitor of tissue factor (TF)/ …
G17DT Immunogen is a vaccine that neutralizes gastrin-17, a hormone required for the growth of a number of cancers of the gastrointestinal tract. It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine. It is also in a phase II/III trial for...
Investigational
Matched Synonyms: … Gastrin 17C Diphtheria Toxoid Immunogen …
Matched Description: … It is in phase III trials for advanced pancreatic cancer as a monotherapy and in combination with gemcitabine ... It is also in a phase II/III trial for advanced stomach cancer in combination with 5-fluorouracil and ... cisplatin and in a late phase II trial for advanced colorectal cancer in combination with irinotecan …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Proteins ... Nerve Tissue Proteins
Displaying drugs 726 - 750 of 1155 in total