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Displaying drugs 726 - 750 of 782 in total
Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Investigational
Matched Synonyms: … MOLECULE 1, EC 3.2.1.35) PRECURSOR-(36-482)-PEPTIDE (MATURE (1-447)-PEPTIDE), PRODUCED IN CHINESE HAMSTER OVARY
Matched Description: … Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And
Matched Categories: … Enzymes and Coenzymes …
Etavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
Investigational
Matched Synonyms: … 1-propanone, 1-(5-((2,3-dihydro-1,4-dioxino(2,3-b)pyridin-7-yl)sulfonyl)-3,4,5,6-tetrahydropyrrolo(3,4 …
Matched Iupac: … (2S)-1-(5-{2H,3H-[1,4]dioxino[2,3-b]pyridine-7-sulfonyl}-1H,2H,3H,4H,5H,6H-pyrrolo[3,4-c]pyrrol-2-yl) …
Experimental
Matched Name: … 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and
Matched Categories: … Calcium-Regulating Hormones and Agents ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … VESNAR
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives …
Matched Products: … VISCAL
Experimental
Matched Name: … 2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE
Amaranthus retroflexus whole allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Red-root amaranth whole …
Experimental
Matched Name: … 6-CHLORO-3-(DICHLOROMETHYL)-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE 1,1-DIOXIDE
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide ... formoterol, glycopyrronium bromide and budesonide …
Matched Products: … B-CORT ® 50 ... B-CORT® 200 AEROSOL ... B-CORT ACUSO 50 MCG. …
Investigational
Matched Synonyms: … -CHOLEST-5-EN-3-YLOXY)-19,39,42-TRIHYDROXY-19,39-DIOXIDO-58-OXO-3,6,9,12,15,18,20,23,26,29,32,35,38,40,44,47,50,53 …
Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and
Matched Salts name: … Pantoprazole magnesium ... Pantoprazole magnesium dihydrate ... Pantoprazole magnesium hemipentahydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Medications that reduce magnesium levels ... pantoprazole, amoxicillin and clarithromycin ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... pantoprazole, amoxicillin, clarithromycin and metronidazole …
Matched Products: … Pantoprazole Magnesium ... Teva-pantoprazole Magnesium
Amoxicillin, or BRL-2333, is a penicillin G derivative first described in the literature in 1972. Amoxicillin has similar activity to penicillin and ampicillin, but leads to higher serum concentrations than ampicillin. Amoxicillin was granted FDA approval on 18 January 1974.
Approved
Vet approved
Matched Description: … [A190648] Amoxicillin has similar activity to [penicillin] and [ampicillin], but leads to higher serum …
Matched Mixtures name: … Clavulin 125 F Oral Sus ... Clavulin 250 F Oral Sus ... Amoxicillin/Clav Pot Oral Susp
Matched Categories: … Medications that reduce magnesium levels ... Alimentary Tract and Metabolism ... vonoprazan and amoxicillin ... rabeprazole, amoxicillin and clarithromycin ... vonoprazan, amoxicillin and clarithromycin …
Matched Products: … Nu-amoxi Sus 125/5ml ... Nu-amoxi Sus 250mg/5ml ... Amox S 250 Sus 250mg/5ml …
Human alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Approved
Matched Synonyms: … API ... Wap four-disulfide core domain protein 4 …
Matched Description: … inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Enzymes and Coenzymes …
Experimental
Matched Name: … (3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched International brands: … Montene
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MONTHAN ... MONTAS-10 FILM COATED TABLET 10 MG …
Experimental
Matched Name: … (4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide
Experimental
Matched Name: … BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE …
Matched Iupac: … methyl-5-[4-({[(2s,5s)-2-carboxy-2-methyl-1,3-dioxan-5-yl]oxy}carbonyl)piperazine-1-carbonyloxy]-1,3-dioxane
Experimental
Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Description: … ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in ... 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and ... solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MINIRIN TABLET 0.1 mg (Oval) …
Investigational
Matched Synonyms: … Active principle of the pars intermedia of the pituitary
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Pituitary Hormones ... Pituitary Hormones, Anterior …
Experimental
Matched Name: … Bis-1,2-{[(Z)-2-carboxy-2-methyl-1,3-dioxane]-5-yloxycarbamoyl}-ethane …
Matched Iupac: … 5-({[2-({[(2-carboxy-2-methyl-1,3-dioxan-5-yl)oxy]carbonyl}amino)ethyl]carbamoyl}oxy)-2-methyl-1,3-dioxane
Experimental
Matched Name: … cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched International brands: … Av-Cor ... K-Cor
Matched Description: … It is shown to dilate normal and stenotic coronary arteries and reduces both ventricular preload and ... , most of Europe, India, Philippines, Japan, South Korea, and Taiwan. ... Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia …
Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas bubbles to facilitate their elimination. It has a favourable safety profile as it is not systemically absorbed. Simethicone has been in use since the 1940s but was granted FDA approval in 1952.
Approved
Matched Description: … Simethicone is a silicon based surfactant that decreases the surface tension of gastrointestinal gas …
Matched Mixtures name: … Gelusil Antacid and Anti-gas ... MAGNELUM COMPUESTO ... ALUMINIO HIDRÓXIDO - MAGNESIO HIDRÓXIDO - SIMETICONA …
Matched Categories: … Silicones ... Silicon Compounds …
Matched Products: … VELGASTIN BLAEHUNGEN SUS
Displaying drugs 726 - 750 of 782 in total