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Displaying drugs 726 - 750 of 1289 in total
Experimental
Illicit
Matched Name: … 4-Bromo-2,5-dimethoxyamphetamine …
Matched Iupac: … 1-(4-bromo-2,5-dimethoxyphenyl)propan-2-amine …
Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Description: … through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and ... In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under ... Marketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor …
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and
Matched Mixtures name: … Promethazine Hydrochloride and Dextromethorphan Hydrobromide ... Meperidine Hcl and Promethazine Hcl ... Promethazine Hydrochloride and Codeine Phosphate …
Matched Categories: … prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … LENIL ANTIPRURITO …
Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life. Interferon...
Approved
Investigational
Matched Synonyms: … Interferon beta ... Interferon-beta ... HUMAN INTERFERON BETA
Matched Name: … Human interferon beta
Matched Description: … (MS), and was initially approved by the FDA in 1992. ... [L12081] Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and ... Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Human interferon beta (166 residues), glycosylated, MW=22.5kD. It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta gene has been introduced. The amino acid sequence is identical to that of natural human interferon beta.
Approved
Investigational
Matched Synonyms: … Interferon beta 1-a ... Interferon beta 1a ... Interferon beta-1a …
Matched Name: … Interferon beta-1a …
Matched Description: … Human interferon beta (166 residues), glycosylated, MW=22.5kD. ... The amino acid sequence is identical to that of natural human interferon beta. ... It is produced by mammalian cells (Chinese Hamster Ovary cells) into which the human interferon beta
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon-beta ... interferon beta-1a …
Matched Products: … AVONEX®INTERFERON BETA-1A JERINGA PRELLENADA …
Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD
Approved
Matched Synonyms: … Interferon beta-1b ... Interferon-beta-1b ... Interferon beta 1b (recombinant) …
Matched Name: … Interferon beta-1b …
Matched Description: … Human interferon beta (165 residues), cysteine 17 is substituted with serine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon-beta ... interferon beta-1b …
Ragifilimab is under investigation in clinical trial NCT04225039 (Anti-gitr/anti-pd1/stereotactic Radiosurgery, in Recurrent Glioblastoma).
Investigational
Matched Synonyms: … Incagn-01876 …
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … LENTA . NFUSIÓN I.V. …
Investigational
Matched Synonyms: … 8-Bromo-2-((1-methylpiperidin-4-yl)amino)-4-((4-phenoxyphenyl)amino)pyrido[4,3-D]pyrimidin-5(6H)-one ... 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-(4-phenoxyanilino)-6H-pyrido[4,3-d]pyrimidin-5-one …
Matched Iupac: … 8-bromo-2-[(1-methylpiperidin-4-yl)amino]-4-[(4-phenoxyphenyl)amino]-5H,6H-pyrido[4,3-d]pyrimidin-5-one …
NS3728 is an orally active chloride channel blocker for the treatment of cancer.
Investigational
Matched Synonyms: … N-[4-bromo-2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-N'-[3,5-bis(trifluoromethyl)phenyl]urea …
Matched Iupac: … 1-[3,5-bis(trifluoromethyl)phenyl]-3-[5-bromo-2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]urea …
Experimental
Matched Synonyms: … O-(N-Acetyl-alpha-neuraminosyl)-(2->3)-o-beta-D-galactopyranosyl-(1->4)-alpha-D-glucopyranose …
Matched Name: … 3'-beta-Sialyl-beta-lactose …
Experimental
Matched Name: … 1-(2-Fluorobenzyl)-3-Butyl-8-(N-Acetyl-4-Aminobenzyl)-Xanthine
Experimental
Illicit
Matched Name: … 4-Bromo-2,5-dimethoxyphenethylamine …
Matched Iupac: … 2-(4-bromo-2,5-dimethoxyphenyl)ethan-1-amine …
Experimental
Matched Name: … 3-Bromo-7-Nitroindazole …
Matched Iupac: … 3-bromo-7-nitro-1H-indazole …
Experimental
Matched Name: … 12-Bromo-1-dodecanol …
Experimental
Matched Name: … Beta-Hydroxyleucine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
beta-Alanine is an amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported.
Experimental
Matched Synonyms: … beta-Alanine …
Matched Name: … beta-Alanine …
Matched Description: … beta-Alanine is an amino acid formed in vivo by the degradation of [dihydrouracil] and [carnosine]. ... Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound ... may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Name: … beta-Hydroxyasparagine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … beta-Escin ... beta-Aescin …
Matched Name: … beta-Escin …
Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase).
Investigational
Matched Synonyms: … Idursulfase beta ... Idursulfase .beta. ... Iduronate 2-sulfatase (a-l-iduronate sulfate sulfatase), human proenzyme produced in cho cells (glycoform beta
Matched Name: … Idursulfase beta
Matched Description: … Idursulfase beta is under investigation in clinical trial NCT01645189 (Safety and Efficacy of Hunterase …
Matched Categories: … Alimentary Tract and Metabolism ... idursulfase beta ... Enzymes and Coenzymes …
VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline (GSK) and Sanofi Pasteur. It comprises a recombinant SARS-CoV-2 spike protein (B.1.351 strain) - produced by recombinant DNA technology using a baculovirus expression system in an insect cell line that is derived from Sf9 cells of the fall...
Approved
Investigational
Matched Name: … VidPrevtyn Beta
Matched Description: … (GSK) and Sanofi Pasteur. ... VidPrevtyn Beta is an adjuvanted, recombinant COVID-19 vaccine developed collaboratively by GlaxoSmithKline ... [A245829,L49696] In October 2022, VidPrevtyn Beta was approved in the European Union for use as a …
Dyphylline is a theophylline derivative with broncho- and vasodilator properties. It is typically used in the management of asthma, cardiac dyspnea, and bronchitis.
Approved
Matched Synonyms: … 1,3-dimethyl-7-(2,3-dihydroxypropyl)xanthine
Matched Description: … Dyphylline is a theophylline derivative with broncho- and vasodilator properties. ... It is typically used in the management of asthma, cardiac dyspnea, and bronchitis. …
Matched Mixtures name: … Dyphylline and Guaifenesin …
Matched Categories: … Xanthines and Adrenergics ... diprophylline and adrenergics ... Xanthine derivatives …
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Experimental
Matched Synonyms: … beta-Estradiol-17-beta-hemisuccinate ... beta-Estradiol-17beta-hemisuccinate …
Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system, disrupting communication between the brain and other parts of the body. Most patients diagnosed with this illness experience their initial disease symptoms between the age of 20 to 40, often the most productive years of...
Approved
Matched Synonyms: … PEG IFN-beta-1a ... Peginterferon beta-1a ... Polyethylene glycol-interferon beta-1a …
Matched Name: … Peginterferon beta-1a …
Matched Description: … Multiple Sclerosis (MS) is a chronic and inflammatory autoimmune disease of the central nervous system ... , disrupting communication between the brain and other parts of the body. ... muscle twitching, vision disturbance, and depressing or mood swings. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins ... Interferon-beta ... peginterferon beta-1a …
Displaying drugs 726 - 750 of 1289 in total