Displaying drugs 726 - 750 of 2709 in total
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … Obeticholic acid ... 6-ethylchenodeoxycholic acid ... 6α-ethylchenodeoxycholic acid …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Matched Name: … Obeticholic acid …
Matched Iupac: … 11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected ... Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... in patients with PBC and advanced cirrhosis (e.g. those with portal hypertension or hepatic decompensation …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Sinapic acid
Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. It is also a constituent of propolis.
Experimental
Matched Synonyms: … Sinapinic acid ... trans-sinapic acid ... (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)-2-propenoic acid …
Matched Name: … Sinapic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Indicators and Reagents ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Sinapic acid …
Matched Iupac: … (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid …
Matched Description: … Sinapic acid is a matrix for matrix-assisted laser desorption technique for protein MW determination. …
Matched Categories: … Indicators and Reagents ... Carboxylic Acids ... Acids, Carbocyclic …
4-(Dimethylamino)benzoic acid
Experimental
Matched Synonyms: … N,N-Dimethyl-4-aminobenzoic acid ... p-Dimethylamino benzoic acid ... N,N-Dimethyl-p-aminobenzoic acid …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Name: … 4-(Dimethylamino)benzoic acid …
Matched Iupac: … 4-(dimethylamino)benzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Ketoprofen
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Approved
Vet approved
Matched Synonyms: … 3-Benzoylhydratropic acid ... 2-(3-Benzoylphenyl)propionic acid ... m-Benzoylhydratropic acid …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Vopac - Ketoprofen, Lidocaine Hydrochloride Pac …
Matched Iupac: … 2-(3-benzoylphenyl)propanoic acid …
Matched Description: … and antipyretic properties. ... Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Ketoprofen and isomer ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Vopac - Ketoprofen, Lidocaine Hydrochloride Pac …
Doconexent
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … cervonic acid ... Docosahexanoic Acid ... Docosahexaenoic acid …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... Calcium PNV ... Folet DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Matched Iupac: … (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoic acid …
Matched Description: … A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … Iron Polysaccharides Folic Acid DHA ... Calcium PNV ... Folet DHA …
Matched Categories: … Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Idroxioleic acid
Investigational
Matched Synonyms: … 2-hydroxyoleic acid ... Alpha-hydroxyoleic acid ... (z)-2-hydroxyoctadec-9-enoic acid …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Matched Name: … Idroxioleic acid …
Matched Iupac: … (9Z)-2-hydroxyoctadec-9-enoic acid …
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Synonyms: … 4-aminohippuric acid ... Aminohippuric acid ... p-aminohippuric acid …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries ... Acids, Carbocyclic ... Keto Acids …
Matched Name: … Aminohippuric acid …
Matched Iupac: … 2-[(4-aminophenyl)formamido]acetic acid …
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory ... The glycine amide of 4-aminobenzoic acid. …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries ... Acids, Carbocyclic ... Keto Acids …
N,N-dimethylglycine
Experimental
Matched Synonyms: … (dimethylamino)acetic acid ... 2-(Dimethylamino)acetic acid ... N,N-Dimethylaminoacetic acid …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Iupac: … 2-(dimethylamino)acetic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Nitrilotriacetic acid
Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.)
Experimental
Matched Synonyms: … Triglycollamic acid ... nitrilo-2,2',2''-triacetic acid ... α,α',α''-trimethylaminetricarboxylic acid …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Nitrilotriacetic acid …
Matched Iupac: … 2-[bis(carboxymethyl)amino]acetic acid …
Matched Description: … Nitrilotriacetic acid is a derivative of acetic acid, N(CH2COOH)3. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Acids, Acyclic ... Carboxylic Acids …
Iron isomaltoside 1000
Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer, Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others.
Approved
Investigational
Matched Name: … Iron isomaltoside 1000 …
Matched Description: … , Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others. ... Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer ... Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. …
Matched Categories: … Iron Compounds …
Matched Description: … , Esophageal Cancer, Chronic Kidney Disease, and Anemia, Iron-Deficiency, among others. ... Iron isomaltoside 1000 has been investigated for the treatment and basic science of Anemia, Gastric Cancer ... Iron isomaltoside 1000 is under investigation in Iron Deficiency Anaemia. …
Matched Categories: … Iron Compounds …
Tetrahydrofolic acid
Tetrahydrofolic acid is a folic acid derivative that is produced from dihydrofolic acid after conversion by dihydrofolate reductase. It is converted into 5,10-methylenetetrahydrofolate by serine hydroxymethyltransferase. It is a soluble coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids.
Nutraceutical
Matched Synonyms: … 5,6,7,8-tetrahydrofolic acid …
Matched Name: … Tetrahydrofolic acid …
Matched Iupac: … -[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … It is a soluble coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids ... Tetrahydrofolic acid is a folic acid derivative that is produced from dihydrofolic acid after conversion …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes …
Matched Name: … Tetrahydrofolic acid …
Matched Iupac: … -[(4-{[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid …
Matched Description: … It is a soluble coenzyme in many reactions, especially in the metabolism of amino acids and nucleic acids ... Tetrahydrofolic acid is a folic acid derivative that is produced from dihydrofolic acid after conversion …
Matched Categories: … Folic Acid and Derivatives ... Enzymes and Coenzymes …
Isocitric Acid
Experimental
Matched Name: … Isocitric Acid …
Matched Iupac: … (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Categories: … Citrates ... Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Matched Iupac: … (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylic acid …
Matched Categories: … Citrates ... Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids …
Kojic acid
Experimental
Matched Name: … Kojic acid …
Matched Mixtures name: … Ultra-Potent 2% Kojic Acid Glowing …
Matched Mixtures name: … Ultra-Potent 2% Kojic Acid Glowing …
Quinolinic Acid
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS. [PubChem]
Experimental
Matched Name: … Quinolinic Acid …
Matched Iupac: … pyridine-2,3-dicarboxylic acid …
Matched Description: … Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits …
Matched Categories: … Quinolinic Acids …
Matched Iupac: … pyridine-2,3-dicarboxylic acid …
Matched Description: … Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits …
Matched Categories: … Quinolinic Acids …
Glycochenodeoxycholic Acid
A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic. [PubChem]
Experimental
Matched Name: … Glycochenodeoxycholic Acid …
Matched Iupac: … 11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]acetic acid …
Matched Description: … It is a cholagogue and choleretic. [PubChem] ... A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. ... It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … Bile Acids and Salts ... Amino Acids, Peptides, and Proteins ... Amino Acids ... Cholic Acids ... Glycodeoxycholic Acid …
Matched Iupac: … 11aR)-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]acetic acid …
Matched Description: … It is a cholagogue and choleretic. [PubChem] ... A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. ... It acts as a detergent to solubilize fats for absorption and is itself absorbed. …
Matched Categories: … Bile Acids and Salts ... Amino Acids, Peptides, and Proteins ... Amino Acids ... Cholic Acids ... Glycodeoxycholic Acid …
Dihydroorotic Acid
Experimental
Matched Name: … Dihydroorotic Acid …
Matched Iupac: … (4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid …
Matched Iupac: … (4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid …
Malonic acid
Experimental
Matched Synonyms: … Propanedioic acid …
Matched Name: … Malonic acid …
Matched Iupac: … propanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Malonic acid …
Matched Iupac: … propanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Benzoylformic Acid
Experimental
Matched Name: … Benzoylformic Acid …
Matched Iupac: … 2-oxo-2-phenylacetic acid …
Matched Categories: … Acids, Aldehydic ... Hydroxy Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … 2-oxo-2-phenylacetic acid …
Matched Categories: … Acids, Aldehydic ... Hydroxy Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Aminobenzoic acid
A member of the vitamin B complex. It used to be common in sunscreening agents until found to also be a sensitizer. The potassium salt is used therapeutically in fibrotic skin disorders.
Approved
Experimental
Matched Synonyms: … 4-aminobenzoic acid ... Aminobenzoic acid ... p-Aminobenzoic acid …
Matched Name: … Aminobenzoic acid …
Matched Iupac: … 4-aminobenzoic acid …
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... Acids, Carbocyclic ... Carboxylic Acids ... aminobenzoic acid …
Matched Name: … Aminobenzoic acid …
Matched Iupac: … 4-aminobenzoic acid …
Matched Categories: … Emollients and Protectives ... 4-Aminobenzoic Acid ... Acids, Carbocyclic ... Carboxylic Acids ... aminobenzoic acid …
Hydrogenobyrinic acid
Experimental
Matched Synonyms: … Hydrogenobyrinic acid …
Matched Name: … Hydrogenobyrinic acid …
Matched Iupac: … tetraazapentacyclo[15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5,7(22),10,12(21),15,17(20)-hexaen-9-yl]propanoic acid …
Matched Name: … Hydrogenobyrinic acid …
Matched Iupac: … tetraazapentacyclo[15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5,7(22),10,12(21),15,17(20)-hexaen-9-yl]propanoic acid …
Deoxyamidinoproclavaminic acid
Experimental
Matched Synonyms: … Deoxyguanidinoproclavaminic acid …
Matched Name: … Deoxyamidinoproclavaminic acid …
Matched Iupac: … (2S)-5-carbamimidamido-2-(2-oxoazetidin-1-yl)pentanoic acid …
Matched Name: … Deoxyamidinoproclavaminic acid …
Matched Iupac: … (2S)-5-carbamimidamido-2-(2-oxoazetidin-1-yl)pentanoic acid …
Cholic Acid
A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion. [PubChem]
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid...
Approved
Matched Synonyms: … Cholic Acid …
Matched Name: … Cholic Acid …
Matched Iupac: … 11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. ... [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug ... Administration as a treatment for children and adults with bile acid synthesis disorders due to single …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Matched Name: … Cholic Acid …
Matched Iupac: … 11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … A major primary bile acid produced in the liver and usually conjugated with glycine or taurine. ... [PubChem] Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug ... Administration as a treatment for children and adults with bile acid synthesis disorders due to single …
Matched Categories: … Bile Acids and Salts ... Bile acids and derivatives ... Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Cholic Acids …
Phthalic Acid
Experimental
Matched Name: … Phthalic Acid …
Matched Iupac: … benzene-1,2-dicarboxylic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … benzene-1,2-dicarboxylic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Displaying drugs 726 - 750 of 2709 in total