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Displaying drugs 726 - 750 of 2496 in total
Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Synonyms: … Colistin methanesulfonic acid ... Colistinmethanesulfonic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 2-Ketoisovaleric acid ... Dimethylpyruvic acid ... α-oxoisovaleric acid
Matched Iupac: … 3-methyl-2-oxobutanoic acid
Matched Categories: … Carboxylic Acids ... Pentanoic Acids
Experimental
Matched Synonyms: … Asclepic acid ... (Z)-11-octadecenoic acid ... (Z)-octadec-11-enoic acid
Matched Name: … cis-Vaccenic acid
Matched Iupac: … (11Z)-octadec-11-enoic acid
Matched Categories: … Fatty Acids ... Fatty Acids, Unsaturated ... Fatty Acids, Monounsaturated …
Experimental
Matched Synonyms: … Dimethylarsenic acid ... Dimethylarsinic acid
Matched Name: … Cacodylic acid
Matched Iupac: … dimethylarsinic acid
Defibrotide is the sodium salt of a mixture of single-stranded oligodeoxyribonucleotides derived from porcine mucosal DNA. It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without associated significant systemic anticoagulant effects). It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of...
Approved
Investigational
Matched Synonyms: … Defibrotide free acid ... Defibrotide free acid (porcine) ... Defibrotide free acid (porcine mucosa) …
Matched Description: … It has been shown to have antithrombotic, anti-inflammatory and anti-ischemic properties (but without ... It is marketed under the brand names Dasovas (FM), Noravid, and Prociclide in a variety of countries. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
Experimental
Matched Synonyms: … DL-threonic acid ... Threo-2,3,4-trihydroxybutyric acid ... 2,3,4-Trihydroxy-(threo)-butanoic acid
Matched Name: … Threonic acid
Matched Iupac: … (2S,3R)-2,3,4-trihydroxybutanoic acid
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
The α-anomer of D-galacturonic acid.
Experimental
Matched Synonyms: … α-D-galacturonic acid ... α-D-galactopyranuronic acid ... alpha-D-galactopyranuronic acid
Matched Name: … alpha-D-galacturonic acid
Matched Iupac: … (2S,3R,4S,5R,6S)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Matched Description: … The α-anomer of D-galacturonic acid. …
Teprotumumab is a fully human IgG1 monoclonal antibody directed against the human insulin-like growth factor-1 receptor. Following a clinical trial in which its efficacy in the treatment of thyroid eye disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016 and was approved by the FDA...
Approved
Investigational
Matched Synonyms: … Immunoglobulin G1, anti-(human insulin-like growth factor I receptor) (human monoclonal heavy chain), …
Matched Description: … disease (TED) was assessed, it received "breakthrough therapy" designation from the FDA in 2016[A190129] and ... tissue remodeling behind the eye, and previous treatment options typically involved multiple invasive ... Thyroid eye disease is a potentially debilitating complication of Graves' Disease involving inflammation and
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Insulin-like Growth Factor-1 Receptor Inhibitor ... Insulin-like Growth Factor-1 Receptor Inhibitors …
Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ak109 …
Matched Description: … Pulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and
Apitegromab is under investigation in clinical trial NCT03921528 (An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy).
Investigational
Matched Synonyms: … Immunoglobulin g4 (234-proline), anti-(human progrowth differentiation factor 8) (human monoclonal srk …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 2-aminoisobutyric acid ... α-aminoisobutyric acid ... α-aminoisobutanoic acid
Matched Name: … 2-aminoisobutyric acid
Matched Iupac: … 2-amino-2-methylpropanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Amino Acids, Branched-Chain …
Experimental
Matched Synonyms: … 1-Naphthylacetic acid ... naphthalene-1-acetic acid ... α-naphthaleneacetic acid
Matched Name: … 1-naphthaleneacetic acid
Matched Iupac: … 2-(naphthalen-1-yl)acetic acid
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 3-phenoxyhydratropic acid ... (+/-)-m-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS …
Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab Ophthalmic Suspension for the Treatment of Dry Eye Disease).
Investigational
Matched Synonyms: … immunoglobulin scFv, anti-[Homo sapiens TNF (tumor necrosis factor, TNFSF2, DIF, TNF-alpha)], humanized ... Immunoglobulin, anti-(human tumor necrosis factor α)(human-Oryctolagus cuniculus monoclonal ESBA1622 …
Matched Description: … Licaminlimab is under investigation in clinical trial NCT05896670 (Safety and Efficacy of Licaminlimab …
Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED)).
Investigational
Matched Synonyms: … Immunoglobulin g1 (de-c-terminal-lysine), anti-(human insulin-like growth factor i receptor) (human-mus ... Immunoglobulin g1-kappa, anti-(homo sapiens igf1r (insulin like growth factor 1 receptor, igf1-r, igf …
Matched Description: … Lonigutamab is under investigation in clinical trial NCT05683496 (Efficacy and Safety of Lonigutamab …
Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too. GM-CSF stimulates proliferation, activation and differentiation of...
Investigational
Matched Synonyms: … Colony-stimulating factor 2 (human clone pCSF-1 protein moiety reduced), glycoform GMC 89-107 …
Matched Description: … Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and ... GM-CSF stimulates proliferation, activation and differentiation of macrophages and granulocytes and their ... Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins ... Biological Factors ... Colony-Stimulating Factors ... Hematopoietic Cell Growth Factors
Experimental
Matched Synonyms: … (R)-(+)-Tetrahydro-2-furoic acid ... (S)-(-)-2-Tetrahydrofuroic acid ... (2R)-Tetrahydro-2-furancarboxylic acid
Matched Name: … (S)-2-Tetrahydrofuroic acid
Matched Iupac: … (2R)-oxolane-2-carboxylic acid
Experimental
Matched Synonyms: … Thiazolidinecarboxylic acid ... (4R)-4-Thiazolidinecarboxylic acid ... (R)-4-Thiazolidinecarboxylic acid
Matched Iupac: … (4R)-1,3-thiazolidine-4-carboxylic acid
Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction.
Investigational
Matched Synonyms: … 10-methylfolic acid ... N10-methylfolic acid ... 10-methylpteroylglutamic acid
Matched Iupac: … -2-[(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid
Matched Description: … Methopterin is thought to have effects on osteoclasts and to inhibit inflammatory bone destruction. …
Experimental
Matched Synonyms: … 3-morpholinopropanesulfonic acid ... Morpholinopropane sulfonic acid
Matched Name: … 3-(N-morpholino)propanesulfonic acid
Matched Iupac: … 3-(morpholin-4-yl)propane-1-sulfonic acid
Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Synonyms: … Tannic acid ... Gallotannic acid
Matched Name: … Tannic acid
Matched Description: … Tannic acid is also taken by mouth and applied directly for bleeding, chronic diarrhea, dysentery, bloody ... and poison ivy. ... and other Quercus species). …
Experimental
Matched Synonyms: … Dichlorocyanuric acid ... Dichloroisocyanuric acid
Experimental
Matched Synonyms: … N-hydroxyformamidoacetic acid ... N-formyl hydroxyaminoacetic acid ... N-formyl-N- hydroxyaminoacetic acid
Matched Iupac: … 2-(N-hydroxyformamido)acetic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Approved
Investigational
Matched Synonyms: … polystyrenesulfonic acid ... Polystyrene sulfonic acid ... poly(styrene-4-sulfonic acid) …
Matched Description: … It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines ... It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Synonyms: … Suberanilohydroxamic acid ... Suberoylanilide hydroxamic acid ... Octanedioic acid hydroxyamide phenylamide …
Matched Description: … Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hydroxy Acids ... Carboxylic Acids ... Hydroxamic Acids
Displaying drugs 726 - 750 of 2496 in total