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Displaying drugs 7601 - 7625 of 10582 in total

N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE

Experimental
Matched Iupac: … (2S)-1-[(8aR)-octahydropyrrolo[1,2-a]pyrimidin-1-yl]-4-methylpentan-2-amine …

Opiranserin

Opiranserin is under investigation in clinical trial NCT03997838 (Evaluate the Efficacy and Safety of VVZ-149 Injections for the Treatment of Post-operative Pain Following Abdominoplasty).
Investigational

Paramethasone

A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than hydrocortisone with supplementary fludrocortisone. (From Martindale, The Extra Pharmacopoeia,...
Experimental
Matched Iupac: … (1R,2R,3aS,3bS,5S,9aR,9bS,10S,11aS)-5-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H …

TPMPA

TPMPA ((1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid) is a selective antagonist of GABAC receptors (also known as GABA-ρ or GABAA-ρ receptors). GABAC receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut.[A245308,A245313] TPMPA is used as a pharmacological...
Experimental

Histidinol

Experimental
Matched Iupac: … (2S)-1-hydroxy-3-(1H-imidazol-5-yl)propan-2-aminium …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Tecastemizole

Investigational
Matched Iupac: … 1-[(4-fluorophenyl)methyl]-N-(piperidin-4-yl)-1H-1,3-benzodiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-599626

BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.
Investigational
Matched Iupac: … [(3S)-morpholin-3-yl]methyl N-[4-({1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}amino)-5-methylpyrrolo[ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Radezolid

Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Imrecoxib

Imrecoxib has been used in trials studying the treatment of Knee Osteoarthritis.
Investigational
Matched Iupac: … 4-(4-methanesulfonylphenyl)-3-(4-methylphenyl)-1-propyl-2,5-dihydro-1H-pyrrol-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-582949

BMS-582949 has been investigated for the treatment of Psoriasis.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Enibomal

Experimental
Matched Iupac: … 5-(2-bromoprop-2-en-1-yl)-1-methyl-5-(propan-2-yl)-1,3-diazinane-2,4,6-trione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Fenoxazoline

Experimental
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-04937319

PF-04937319 is under investigation in clinical trial NCT01513928 (A Study To Compare The Pharmacokinetics Of Different Formulations Of PF-04937319 In Healthy Subjects).
Investigational
Matched Iupac: … N,N-dimethyl-5-({2-methyl-6-[(5-methylpyrazin-2-yl)carbamoyl]-1-benzofuran-4-yl}oxy)pyrimidine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

BMS-791826

BMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).
Investigational
Matched Iupac: … N-ethyl-2-fluoro-N-methyl-4-[(5S)-5-{1-methyl-1-[(1,3,4-thiadiazol-2-yl)carbamoyl]ethyl}-5H-chromeno[ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Freselestat

Experimental
Investigational
Matched Iupac: … 2-(5-amino-6-oxo-2-phenyl-1,6-dihydropyrimidin-1-yl)-N-[(1R,2R)-1-(5-tert-butyl-1,3,4-oxadiazol-2-yl) ... -1-hydroxy-3-methylbutan-2-yl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-517717

LY517717 is an investigational oral direct inhibitor of activated Factor Xa. It is believed to be Lilly's PMD-3112 (licensed from Amgen).
Investigational
Matched Iupac: … N-[(1R)-2-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-2-oxo-1-phenylethyl]-1H-indole-6-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Ravuconazole

Investigational
Matched Iupac: … 4-{2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl} …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Efrotomycin

Vet approved
Matched Iupac: … -1-yl]butanimidic acid ... yl]oxan-2-yl]-N-[(2E,4E)-7-{3,4-dihydroxy-5-[(1E,3E,5E)-7-hydroxy-6-methyl-7-[(3Z)-1-methyl-2,4-dioxo ... dimethoxy-6-methyloxan-2-yl)oxy]-4-methoxy-6-methyloxan-2-yl}oxy)-5,5-dimethyl-6-[(1E,3E)-penta-1,3-dien-1- ... -1,2,3,4-tetrahydropyridin-3-ylidene]hepta-1,3,5-trien-1-yl]oxolan-2-yl}-6-methoxy-5-methylocta-2,4-dien …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pyridoxamine

Pyridoxamine has been used in trials studying the treatment of Kidney Stones.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Alvelestat

Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

CERC-301

Mk 0657 has been used in trials studying the treatment of Major Depressive Disorder.
Investigational
Matched Iupac: … (4-methylphenyl)methyl (3S,4R)-3-fluoro-4-{[(pyrimidin-2-yl)amino]methyl}piperidine-1-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …

LY-2886721

LY2886721 has been used in trials studying the basic science of Alzheimer's Disease.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

Pyroxamide

Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

PF-03814735

PF-03814735 has been used in trials studying the treatment of Solid Tumors.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …

X-396

X-396 has been used in trials studying the treatment of Advanced Solid Tumors and Non-small Cell Lung Cancer.
Investigational
Matched Iupac: … 6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 7601 - 7625 of 10582 in total