Displaying drugs 751 - 775 of 2720 in total
2,2-Dimethylbutyrate
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Iupac: … 2,2-dimethylbutanoic acid …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Oxogluric acid
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … 2-Ketoglutaric acid ... 2-oxoglutaric acid ... Ketoglutaric acid …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Matched Name: … Oxogluric acid …
Matched Iupac: … 2-oxopentanedioic acid …
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids …
Furazolidone
A nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. (From Martindale, The Extra Pharmacopoeia, 30th ed, p514)
Experimental
Vet approved
Matched Synonyms: … N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone ... 5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine ... N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one …
Matched Description: … A nitrofuran derivative with antiprotozoal and antibacterial activity. ... Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. …
Matched Categories: … Nitro Compounds ... metronidazole and furazolidone ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiparasitic Products, Insecticides and Repellents …
Matched Description: … A nitrofuran derivative with antiprotozoal and antibacterial activity. ... Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase. …
Matched Categories: … Nitro Compounds ... metronidazole and furazolidone ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiparasitic Products, Insecticides and Repellents …
(R)-Mandelic acid
Experimental
Matched Synonyms: … (−)-mandelic acid ... (−)-(R)-mandelic acid ... D-mandelic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Matched Name: … (R)-Mandelic acid …
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid …
Epimedium grandiflorum top
Epimedium grandiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Epimedium Grandiflorum Leaf/stem …
Thiosalicylic acid
Experimental
Matched Synonyms: … 2-Thiosalicylic acid ... 2-Mercaptobenzoic acid ... o-Benzoic acid thiol …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Thiosalicylic acid …
Matched Iupac: … 2-sulfanylbenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids …
Foscarnet
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Synonyms: … Carboxyphosphonic acid ... Phosphonoformic acid ... Phosphonomethanoic acid …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … phosphonoformic acid …
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Phosphonic Acid Derivatives ... Nucleic Acid Synthesis Inhibitors …
Citraconic acid
Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid, or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid.
Experimental
Matched Synonyms: … 2-methylmaleic acid ... Methylmaleic acid ... α-methylmaleic acid …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Citraconic acid …
Matched Iupac: … (2Z)-2-methylbut-2-enedioic acid …
Matched Description: … Citraconic acid is one of the isomeric dicarboxylic acids produced by the distillation of citric acid ... , or as metabolites by microorganisms, cis-CH3-C(CO2H)=CHCO2H; the trans-isomer is mesaconic acid. …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Dehydrocholic acid
Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Synonyms: … Dehydrocholic acid ... 3,7,12-triketocholanic acid ... 3,7,12-trioxocholanic acid …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Matched Name: … Dehydrocholic acid …
Matched Iupac: … 9aS,9bS,11aR)-9a,11a-dimethyl-4,7,11-trioxo-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid …
Matched Description: … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with ... chromic acid [A33022]. ... The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids …
Trimesic acid
Experimental
Matched Synonyms: … Trimesinic acid ... Trimesitinic acid ... 5-carboxyisophthalic acid …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Name: … Trimesic acid …
Matched Iupac: … benzene-1,3,5-tricarboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
3',3-diselenodipropionic acid
Investigational
Matched Synonyms: … Diselenodipropionic acid ... 3',3-diseleno dipropionic acid ... Diseleno-3,3'-dipropionic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Matched Name: … 3',3-diselenodipropionic acid …
Matched Iupac: … 3-[(2-carboxyethyl)diselanyl]propanoic acid …
Myristic acid
Experimental
Matched Synonyms: … Tetradecanoic acid ... N-tetradecanoic acid ... N-tetradecan-1-oic acid …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Matched Name: … Myristic acid …
Matched Iupac: … tetradecanoic acid …
Matched Categories: … Fatty Acids ... Myristic Acids …
Phenylpyruvic acid
Experimental
Matched Synonyms: … 3-phenylpyruvic acid ... Phenylpyruvic acid ... β-phenylpyruvic acid …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Phenylpyruvic acid …
Matched Iupac: … 2-oxo-3-phenylpropanoic acid …
Matched Categories: … Keto Acids ... Carboxylic Acids ... Acids, Carbocyclic …
D-Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … (−)-lactic acid ... (R)-lactic acid ... (R)-(−)-lactic acid …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … D-Lactic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Ocimum tenuiflorum top
Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Synonyms: … Holy Basil Leaf/stem …
gamma-Hydroxybutyric acid
Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple countries. It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. However, it is important to note that GHB is a designated Orphan drug (in 1985). Today Xyrem is...
Approved
Illicit
Investigational
Matched Synonyms: … 3-carboxypropoxy acid ... oxy-n-butyric acid ... 4-hydroxy-butyric acid …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Hydroxy Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Name: … gamma-Hydroxybutyric acid …
Matched Iupac: … 4-hydroxybutanoic acid …
Matched Description: … It is currently regulated in the US and sold by Jazz Pharmaceuticals under the name Xyrem. ... Gamma hydroxybutyric acid, commonly abbreviated GHB, is a therapeutic drug which is illegal in multiple ... Today Xyrem is a Schedule III drug; however GHB remains a Schedule I drug and the illicit use of Xyrem …
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Hydroxy Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
5-aminonaphthalene-2-sulfonic acid
Experimental
Matched Synonyms: … 1,6-Cleve's acid ... Cleve's β-acid ... 1-naphthylamine-6-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Matched Name: … 5-aminonaphthalene-2-sulfonic acid …
Matched Iupac: … 5-aminonaphthalene-2-sulfonic acid …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … Oxonic Acid ... 5-azaorotic acid ... Allantoxanic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Nitisinone
Nitisinone is a synthetic reversible inhibitor of 4-hydroxyphenylpyruvate dioxygenase. It is used in the treatment of hereditary tyrosinemia type 1. It is sold under the brand name Orfadin.
Approved
Investigational
Matched Synonyms: … 2-(alpha,alpha,alpha-Trifluoro-2-nitro-p-tuluoyl)-1,3-cyclohexanedione …
Matched Iupac: … 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Carboxylic Acids ... Acids, Carbocyclic …
Matched Iupac: … 2-[2-nitro-4-(trifluoromethyl)benzoyl]cyclohexane-1,3-dione …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Carboxylic Acids ... Acids, Carbocyclic …
Isoferulic acid
Experimental
Matched Synonyms: … Hesperetic acid ... Isoferulic acid …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Madecassic acid
Experimental
Matched Synonyms: … Brahmic acid ... 6β-hydroxyasiatic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Phenylbutyric acid
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … Benzenebutyric acid ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Carlumab
Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer.
Investigational
Withdrawn
Matched Synonyms: … Human monoclonal antibody targeting CC-chemokine ligand 2 (CNTO 888) …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … Carlumab has been used in trials studying the treatment of Cancer and Prostate Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
SBT-100
SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody (sdAb). It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma.[L44131,L44136]
Investigational
Matched Synonyms: … Anti-STAT3 B VHH13 single domain antibody …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
Matched Description: … SBT-100 is an anti-signal transducer and activator of transcription 3 (STAT3) B VHH13 single-domain antibody ... It was granted orphan drug designation by the FDA for the treatment of pancreatic cancer and osteosarcoma …
RLYB212
RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia.
Investigational
Matched Synonyms: … Recombinant human IgG monoclonal HPA-1a antibody …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Matched Description: … It is currently being developed by Rallybio for the prevention of fetal and neonatal alloimmune thrombocytopenia ... RLYB212 is a human monoclonal antibody against Antigen-1A Immunoglobulin (HPA-1A). …
Displaying drugs 751 - 775 of 2720 in total