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Displaying drugs 751 - 775 of 3101 in total
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are …
Matched Salts name: … Nebivolol hydrochloride
Matched Categories: … Beta Blocking Agents and Thiazides ... Beta blocking agents and calcium channel blockers ... valsartan and nebivolol ... nebivolol and amlodipine ... nebivolol and thiazides …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride ... VALENDE 5 MG TABLET, 28 ADET …
HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene, mutated in people with phenylketonuria.
Investigational
Matched Synonyms: … Recombinant adeno-associated viral vector serotype HSC expressing human phenylalanine hydroxylase …
Matched Description: … HMI-102 is an investigational gene therapy designed to encode the phenylalanine-4-hydroxylase (PAH) gene …
Experimental
Matched Name: … [PHENYLALANINYL-PROLINYL]-[2-(PYRIDIN-4-YLAMINO)-ETHYL]-AMINE …
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Synonyms: … N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine ... (S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine ... N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
Matched Iupac: … (2S)-3-methyl-2-(N-{[2'-(2H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}pentanamido)butanoic acid
Matched Description: … [A174124] Valsartan is generally well-tolerated with a side-effect profile superior to that of other ... and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. …
Matched Mixtures name: … Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide ... Valsartan and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... Angiotensin II Antagonists and Calcium Channel Blockers ... valsartan and nebivolol ... Angiotensin II receptor blockers (ARBs) and diuretics ... valsartan and diuretics …
Investigational
Matched Synonyms: … Quinine hydrochloride impurity B …
Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational
Matched Synonyms: … Immunoglobulin g1(238-alanine, 239-alanine), anti-(human fcrn receptor) (human monoclonal hl161bkn .gamma …
Matched Description: … Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and
Matched Categories: … Amino Acids, Peptides, and Proteins …
A narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Experimental
Illicit
Matched Synonyms: … Methadyl acetate
Matched Name: … Methadyl acetate
Matched Iupac: … 6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate
Matched Description: … A narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Methadyl acetate hydrochloride
Experimental
Matched Name: … L-Threoninol
Experimental
Matched Name: … Beta-3-Serine
Matched Iupac: … (2S)-3-amino-2-(hydroxymethyl)propanoic acid
Experimental
Matched Name: … Serine-3'-aminoadenosine …
Experimental
Matched Name: … Nitrocefin Acyl-Serine
An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite and potential antineoplastic activities.
Investigational
Matched Synonyms: … Alanosine ... L-Alanosine
Matched Name: … Alanosine
Matched Iupac: … (2S)-2-amino-3-[hydroxy(nitroso)amino]propanoic acid
Matched Description: … An amino acid analogue and antibiotic derived from the bacterium Streptomyces alanosinicus with antimetabolite ... and potential antineoplastic activities. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Experimental
Matched Name: … N-(4-MORPHOLINE)CARBONYL-B-(1-NAPHTHYL)-L-ALANINE-L-LEUCINE BORONIC ACID
Matched Iupac: … (1R)-3-methyl-1-[(2R)-2-[(morpholine-4-carbonyl)amino]-3-(naphthalen-1-yl)propanamido]butyl]boronic acid
Investigational
Matched Synonyms: … 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN) ... 1-193-BACTERICIDAL/PERMEABILITY-INCREASING PROTEIN (132-ALANINE) (HUMAN REDUCED) …
Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. Therapeutically, hydroxyproline is being studied as an an experimental medicine but is approved...
Experimental
Matched Synonyms: … trans-4-Hydroxy-L-proline
Matched Iupac: … (2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
Matched Description: … It is found in collagen and as such it is common in many gelatin products. ... Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis. ... Hydroxyproline is a neutral heterocyclic protein amino acid. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …
Experimental
Matched Name: … Tryptophanyl-5'amp …
Matched Iupac: … acid ... 1H-indol-3-yl)propanoyl]oxy}({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy})phosphinic
Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis).
Investigational
Matched Synonyms: … Zuretinol acetate
Matched Name: … Zuretinol acetate
Matched Iupac: … (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-yl acetate
Matched Description: … Pigmentosa), Retinitis Pigmentosa (RP), and LCA (Leber Congenital Amaurosis). ... Zuretinol acetate has been used in trials studying the treatment of Impaired Dark Adaptation, RP (Retinitis …
Matched Categories: … Carboxylic Acids
Experimental
Matched Synonyms: … Bisoxatin acetate
Matched Name: … Bisoxatin acetate
Matched Iupac: … 4-{2-[4-(acetyloxy)phenyl]-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl}phenyl acetate
Experimental
Matched Synonyms: … Flurandrenolone acetate
Matched Name: … Flurandrenolide acetate
Matched Iupac: … tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-17-en-8-yl]-2-oxoethyl acetate
Chlormadinone acetate is a progesterone derivative first synthesized in 1961. In the US, chlormadinone acetate was formerly marketed as a component of the combination drug products Estalor-21 and C-Quens. However, the use of these drugs was associated with the development of mammary tumors in dogs. In 1972, the FDA withdrew...
Experimental
Withdrawn
Matched Synonyms: … Chlormadinone acetate
Matched Name: … Chlormadinone acetate
Matched Iupac: … -9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Matched Description: … Estalor-21 and C-Quens. ... efficacy and tolerability. ... Chlormadinone acetate is a progesterone derivative first synthesized in 1961. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … Terpineol acetate
Matched Name: … Terpinyl acetate
Matched Iupac: … 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl acetate
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Description: … Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist ... Derived from endogenous GnRH, ganirelix has amino acid substitutions. …
Matched Salts name: … Ganirelix acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Ganirelix Acetate
A synthetic nonapeptide comprising cysteinyl, phenylalanyl, phenylalanyl, glutaminyl, asparaginyl, cysteinyl, prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine residues. Its antidiuretic effects are less than those of vasopressin. It is a non-catecholamine vasoconstrictor used in local anaesthetic injections for dental use, and is...
Experimental
Matched Synonyms: … 2-(L-phenylalanine)-8-L-lysinevasopressin …
Matched Description: … , prolyl, lysyl, and glycinamide residues in sequence, with a disulfide bridge joining the two cysteine ... It is a non-catecholamine vasoconstrictor used in local anaesthetic injections for dental use, and is ... an ingredient of preparations that have been used for treatment of pain and inflammation of the mouth …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Vasopressin and Analogues …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Synonyms: … 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin ... 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin …
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins …
Experimental
Matched Name: … Alpha-Benzyl-Aminobenzyl-Phosphonic Acid
Matched Iupac: … [(R)-(benzylamino)(phenyl)methyl]phosphonic acid
Displaying drugs 751 - 775 of 3101 in total