Displaying drugs 751 - 775 of 1294 in total
Acetic acid C-11
Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).
Investigational
Matched Synonyms: … 11C-ACETATE …
Matched Description: … Using Imaging Studies PET Scan and Cardiac MRI.). ... Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and …
Matched Description: … Using Imaging Studies PET Scan and Cardiac MRI.). ... Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and …
Iluzanebart
Investigational
Matched Synonyms: … Immunoglobulin G1 [296-cysteine,301-glycine,306-cysteine], anti-(human triggering receptor expressed …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Epitalon
Investigational
Matched Synonyms: … Glycine, l-alanyl-l-.alpha.-glutamyl-l-.alpha.-aspartyl- …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
N-(carboxycarbonyl)-D-phenylalanine
N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.
Experimental
Matched Name: … N-(carboxycarbonyl)-D-phenylalanine …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. …
Dibenzyl (carbonylbis{2,1-hydrazinediyl[(2S)-4-methyl-1-oxo-1,2-pentanediyl]})biscarbamate
Experimental
Matched Synonyms: … 1,5-Bis(N-benzyloxycarbonyl-L-leucinyl)carbohydrazide …
Eprodisate
Eprodisate slows the decline of renal function in AA amyloidosis.
Investigational
Matched Synonyms: … Propane-1,3-disulfonate ... Propane-1,3-disulphonate ... Propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
Matched Iupac: … propane-1,3-disulfonic acid …
N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine
Experimental
Matched Synonyms: … Glycyl-L-alpha-amino-epsilon-pimelyl-D-alanyl-D-alanine …
Matched Name: … N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … N-[(6S)-6-Carboxy-6-(glycylamino)hexanoyl]-D-alanyl-D-alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
N-[O-Phosphono-Pyridoxyl]-Isoleucine
Experimental
Matched Name: … N-[O-Phosphono-Pyridoxyl]-Isoleucine …
N-Pyridoxyl-Glycine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Glycine-5-Monophosphate …
N-Pyridoxyl-Threonine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Threonine-5-Monophosphate …
Levacetylmethadol
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Synonyms: … Levomethadyl acetate ... Levo-methadyl acetate ... (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate …
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Levacetylmethadol hydrochloride …
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Levacetylmethadol hydrochloride …
[Methyltelluro]Acetate
[methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. These are organic compounds containing an oxoanion. This medication targets the protein monomeric sarcosine oxidase.
Experimental
Matched Name: … [Methyltelluro]Acetate …
Matched Iupac: … 2-(methyltellanyl)acetate …
Matched Description: … [methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. …
Matched Iupac: … 2-(methyltellanyl)acetate …
Matched Description: … [methyltelluro]acetate is a solid. This compound belongs to the organic oxoanionic compounds. …
Telapristone acetate
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Synonyms: … Telapristone acetate …
Matched Name: … Telapristone acetate …
Matched Iupac: … methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … to alleviate symptoms associated with both uterine fibroids and endometriosis. ... Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development …
Matched Name: … Telapristone acetate …
Matched Iupac: … methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … to alleviate symptoms associated with both uterine fibroids and endometriosis. ... Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development …
Nomegestrol acetate
Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Synonyms: … Nomegestrol acetate ... 17-alpha-Hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate …
Matched Name: … Nomegestrol acetate …
Matched Iupac: … acetyl-5,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … therapy, and for the treatment of gynecological disorders. ... Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
Matched Name: … Nomegestrol acetate …
Matched Iupac: … acetyl-5,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … therapy, and for the treatment of gynecological disorders. ... Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …
Segesterone acetate
Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 . In animal studies, segesterone acetate was shown to be one of the most potent progestins . It mediates progestational activity 100 times higher than that of progesterone ....
Approved
Experimental
Investigational
Matched Synonyms: … Segesterone acetate ... 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate …
Matched Name: … Segesterone acetate …
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative ... Segesterone acetate binds selectively to progesterone receptors and not androgen receptors [A37083]. ... On August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Name: … Segesterone acetate …
Matched Iupac: … methylidene-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate …
Matched Description: … Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative ... Segesterone acetate binds selectively to progesterone receptors and not androgen receptors [A37083]. ... On August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Leukotriene C4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and...
Experimental
Investigational
Matched Synonyms: … )glycine ... ,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl …
Matched Description: … The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular ... (From Dictionary of Prostaglandins and Related Compounds, 1990) …
Matched Description: … The conjugation product of LEUKOTRIENE A4 and glutathione. ... It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular ... (From Dictionary of Prostaglandins and Related Compounds, 1990) …
Brivanib alaninate
Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Investigational
Matched Synonyms: … Brivanib alaninate …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 751 - 775 of 1294 in total