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Displaying drugs 7876 - 7900 of 13162 in total
Experimental
Matched Iupac: … (2R,3S,4S,5R,6R)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …
Experimental
Matched Name: … (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol …
Matched Iupac: … (3R,4S)-1-({4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl}methyl)-4-[(benzylsulfanyl)methyl]pyrrolidin-3-ol …
Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Experimental
Matched Synonyms: … 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone …
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one …
Matched Description: … Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep …
Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated to the cytotoxin mertansine.
Investigational
Matched Synonyms: … Peptide-drug conjugate combining [(Tyr3,Cys8) octreotate amide] and N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl …
Matched Description: … Nendratareotide uzatansine is a peptide-drug conjugate comprising a peptide analog of somatostatin conjugated …
Investigational
Matched Synonyms: … Anti-pd-1 monoclonal antibody gls-010 ... Immunoglobulin g4(231-proline), anti-(human programmed cell death protein 1) (human monoclonal ab122 …
Experimental
Matched Name: … N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE …
Matched Iupac: … -1-yl]pyrrolidine-2-carboxamide ... (2S,4S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)propanamido]butanoyl]-4-phenoxy-N-[(1R)-1,2,3,4-tetrahydronaphthalen …
Experimental
Matched Name: … 4-(4-METHYLPIPERAZIN-1-YL)-N-[5-(2-THIENYLACETYL)-1,5-DIHYDROPYRROLO[3,4-C]PYRAZOL-3-YL]BENZAMIDE …
Matched Iupac: … 4-(4-methylpiperazin-1-yl)-N-{5-[2-(thiophen-2-yl)acetyl]-1H,5H-pyrrolo[3,4-c]pyrazol-3-yl}benzamide …
Experimental
Matched Synonyms: … 2-deoxy-2-fluoro-beta-D-galactose ... 2-FLUORO-2-DEOXY-BETA-D-GALACTOPYRANOSE …
Matched Name: … 2-deoxy-2-fluoro-β-D-galactose …
Experimental
Matched Name: … 5-(2-NITROPHENYL)-2-FUROIC ACID …
Matched Iupac: … 5-(2-nitrophenyl)furan-2-carboxylic acid …
Experimental
Matched Name: … 7,8-Dihydroxy-1-Methoxy-3-Methyl-10-Oxo-4,10-Dihydro-1h,3h-Pyrano[4,3-B]Chromene-9-Carboxylic Acid …
Matched Iupac: … (1R,3S)-7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1H,3H,4H,10H-pyrano[4,3-b]chromene-9-carboxylic acid …
Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type 2.
Investigational
Matched Iupac: … (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)methyl]-6'-(hydroxymethyl)-3H-spiro[2-benzofuran-1,2'-oxane]-3 …
Matched Description: … 2. ... Tofogliflozin has been used in trials studying the treatment and prevention of Diabetes Mellitus Type …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors …
Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl ... )phenyl]-1,2-dihydropyridine-3-carboxamide …
Matched Description: … Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 in Patients With Locally Advanced or Metastatic Solid Tumors).
Investigational
Matched Iupac: … -yl}-1,2-dihydropyridin-2-one ... 1-[(1S)-1-(4-chloro-3-fluorophenyl)-2-hydroxyethyl]-4-{2-[(1-methyl-1H-pyrazol-5-yl)amino]pyrimidin-4 …
Matched Description: … Ravoxertinib is under investigation in clinical trial NCT01875705 (A Dose-Escalation Study of GDC-0994 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fonadelpar is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of SJP-0035 for the Treatment of Patients With Dry Eye Disease).
Investigational
Matched Iupac: … 2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol …
Matched Description: … SJP-0035 for the Treatment of Patients With Dry Eye Disease). ... is under investigation in clinical trial NCT03527212 (A Study to Assess the Safety and Effectiveness of
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … (1-445) (HOMO SAPIENS VH (IGHV2-26*01 (94%) (IGHD)-I ... MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 …
Matched Description: … [A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in ... thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of ... A241050] Narsoplimab is under investigation in clinical trial NCT03205995 (Safety and Efficacy Study of
Experimental
Matched Synonyms: … (1S)-1,4-dideoxy-1,4-imino-1-(9-deazaguanin-9-yl)-D-ribitol …
Matched Iupac: … 2-amino-7-[(2S,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidin-2-yl]-3H,4H,5H-pyrrolo[3,2-d]pyrimidin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-methyloxolane-3,4-diol …
Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. [PubChem]
Experimental
Matched Iupac: … ({[({[(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R,6S)-3,4,6-trihydroxy-5-(sulfoamino)oxan-2-yl]methoxy}sulfonic acid …
Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research to select genetically engineered cells. Resistance to Geneticin is...
Experimental
Matched Iupac: … yl]oxy}-2-hydroxycyclohexyl]oxy}-2-[(1R)-1-hydroxyethyl]oxane-3,4-diol ... amino-6-{[(1R,2S,3S,4R,6S)-4,6-diamino-3-{[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2- …
Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. It is developed by MedImmune for the treatment of Allergic Rhinitis.
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN …
Matched Description: … It is developed by MedImmune for the treatment of Allergic Rhinitis. ... Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic …
Experimental
Matched Synonyms: … 2-(2-Methyl-5-nitroimidazol-1-yl)ethyl benzoate …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl benzoate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … N-Allyl-6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}-N-methyl-1-hexanamine …
Matched Iupac: … (6-{[3-(4-bromophenyl)-1-methyl-1H-indazol-6-yl]oxy}hexyl)(methyl)(prop-2-en-1-yl)amine …
ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH). ARX201 has improved pharmacological...
Investigational
Matched Description: … patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol ... ARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s ... (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino …
is an experimental therapeutic vaccine currently in clinical trial. The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent progression to AIDS.
Investigational
Matched Description: … The aim of therapeutic vaccines is to augment the body's immune response to HIV and to delay or prevent …
Displaying drugs 7876 - 7900 of 13162 in total