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Displaying drugs 776 - 800 of 1266 in total
Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets. Evidence increasingly points to a role for the complement system in TMA.[A241030, A241040] Mannan-associated lectin-binding serine protease-2 (MASP-2) is a major effector in the complement lectin pathway.[A241030,...
Investigational
Matched Synonyms: … MASP-2 antibody ... ANTI-MASP-2 MONOCLONAL ANTIBODY OMS721 ... SERINE PROTEASE 2 (MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASE 2, EC=3.4.21.104) HUMAN MONOCLONAL ANTIBODY
Matched Description: … uremic syndrome, are associated with injury and dysregulation of microvascular endothelium and platelets ... Thrombotic microangiopathies (TMA), including thrombotic thrombocytopenic purpura and atypical hemolytic ... [A241030, A241040] Narsoplimab (OMS721), a human IgG4λ anti-MASP-2 antibody, is under consideration as …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Investigational
Matched Synonyms: … Soluble receptor fused to part of an antibody that is designed to block the growth factor activin a …
FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound IgE (mIgE), causing a depletion of mIgE positive B-cells. It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin E syndrome (HIES).[A258448,L45743]
Investigational
Matched Synonyms: … Recombinant humanized immunoglobulin gamma 1 monoclonal antibody (mAb) directed against the CemX segment …
Matched Description: … It is currently being investigated for immune disorders, such as atopic dermatitis and hyperimmunoglobulin ... FB-825 is an investigational humanized monoclonal antibody that targets the CεmX domain of the membrane-bound …
Investigational
Matched Synonyms: … Fully human monoclonal IgG1 antibody against the type 2 isoform of human Claudin 18 protein (Claudin …
Experimental
Matched Name: … beta-Mannobiose …
Experimental
Matched Name: … beta-cellotriose …
Experimental
Matched Name: … Beta-Hydroxytryptophane …
β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). It may be a chemopreventive agent.
Experimental
Matched Synonyms: … beta-NF …
Matched Name: … beta-Naphthoflavone …
Matched Description: … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and ... induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs). …
Active fraction of Solanum trilobatum; reduces side-effects of radiation-induced toxicity.
Experimental
Matched Name: … beta-Sitosterol …
Experimental
Matched Name: … beta-Pinene …
beta-Apopicropodophyllin is a component of the freshwater plant Micranthemum umbrosum.
Experimental
Matched Synonyms: … beta-Apopicropodophyllin …
Matched Name: … beta-Apopicropodophyllin …
Matched Description: … beta-Apopicropodophyllin is a component of the freshwater plant _Micranthemum umbrosum_. …
Experimental
Matched Name: … (4s-Trans)-4-(Methylamino)-5,6-Dihydro-6-Methyl-4h-Thieno(2,3-B)Thiopyran-2-Sulfonamide-7,7-Dioxide
Experimental
Matched Synonyms: … alpha,beta-MeATP ... alpha,beta-Methylene ATP ... adenosine 5'-[alpha,beta-methylene]triphosphate …
Matched Name: … alpha,beta-Methyleneadenosine 5'-triphosphate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).
Investigational
Matched Synonyms: … Anti-icam-1 monoclonal antibody bi-505 ... lambda, anti-(homo sapiens icam1(intercellular adhesion molecule 1, icam-1, cd54)), human monoclonal antibody
Matched Description: … Bersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule …
Investigational
Matched Synonyms: … (3.beta.,5.beta.,25s)-spirostan-3-ol ... Spirostan-3-ol, (3.beta.,5.beta.,25s)- …
Homosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage...
Approved
Investigational
Matched Description: … It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol ... Homosalate specifically absorbs short-wave UVB rays, which are associated with DNA damage and increased …
Matched Mixtures name: … SOLEIL SUN Creme Solaire Visage et corps Sunscreen Face and Body Sunscreen Broad Spectrum SPF30 ... Adaptasun Sun Care Lotion Sea and Tropics Body / Lait De Soin Solaire Mer Et Tropiques Corps SPF/fps ... Whoa Glow 30 SPF 30 Sunscreen …
Matched Products: … Sei Bella Age Defying Foundation Golden
beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.).
Investigational
Matched Synonyms: … beta-Hydroxy-methylbutyrate …
Matched Name: … beta-Hydroxyisovaleric acid …
Matched Description: … of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.). ... beta-Hydroxyisovaleric acid is under investigation in clinical trial NCT03018496 (Investigating the Effects …
A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
Experimental
Matched Synonyms: … beta-D-glucopyranose ... Beta-D-glucose anhydrous ... Beta-D-glucose, anhydrous …
Matched Name: … Beta-D-Glucose …
Matched Description: … It is naturally occurring and is found in fruits and other parts of plants in its free state. ... It is used therapeutically in fluid and nutrient replacement. …
Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally and pharmacologically related to clopidogrel and ticlopidine. Similar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing...
Approved
Matched Description: … and pharmacologically related to clopidogrel and ticlopidine. ... Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada ... Prasugrel, a thienopyridine derivative, is a platelet activation and aggregation inhibitor structurally …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PRASUGREL BETA 5 MG FTA ... PRASUGREL BETA 10 MG FTA …
Experimental
Matched Name: … BIS-1,2-{[(Z)-2CARBOXY-2-METHYL-1,3-DIOXANE]-5-YLOXYCARBONYL}-PIPERAZINE …
Matched Iupac: … methyl-5-[4-({[(2s,5s)-2-carboxy-2-methyl-1,3-dioxan-5-yl]oxy}carbonyl)piperazine-1-carbonyloxy]-1,3-dioxane
Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria cases.
Approved
Matched Synonyms: … beta-Arteether ... beta-Dihydroartemisinin ethyl ether …
Matched Description: … Artemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting ... schizonticide specifically indicated for the treatment of chloroquine-resistant _Plasmodium falciparum_ malaria and
Matched Categories: … Artemisinin and derivatives ... Antiparasitic Products, Insecticides and Repellents …
β-Methylfentanyl is an analgesic of the opioid class. It is an analog of the potent opioid, fentanyl.
Illicit
Matched Synonyms: … beta-Methylfentanyl …
Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, and Dry Eye Syndrome, among others.
Investigational
Matched Synonyms: … Thymosin beta 4 …
Matched Name: … Thymosin beta-4 …
Matched Description: … and Dry Eye Syndrome, among others. ... Thymosin Beta 4 has been investigated for the treatment of STEMI, Dry Eye, Diabetes, Pressure Ulcers, …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched International brands: … Montene
Matched Description: … others in individuals who used the medication. ... has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … MONTHAN ... MONTAS-10 FILM COATED TABLET 10 MG …
Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] …
Matched Categories: … Calcium-Regulating Hormones and Agents …
Matched Products: … ZONISAMID BETA 25MG ... ZONISAMID BETA 50MG ... ZONISAMID BETA 100MG …
Displaying drugs 776 - 800 of 1266 in total