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Displaying drugs 776 - 800 of 2125 in total

D-Proline

D-proline is an isomer of the naturally occurring amino acid, L-Proline. D-amino acids have been found in relatively high abundance in human plasma and saliva . These amino acids may be of bacterial origin, but there is also evidence that they are endogenously produced through amino acid racemase activity .
Experimental
Matched Synonyms: … (R)-2-Carboxypyrrolidine ... (R)-pyrrolidine-2-carboxylic acid …
Matched Description: … D-amino acids have been found in relatively high abundance in human plasma and saliva [A19262]. ... D-proline is an isomer of the naturally occurring amino acid, L-Proline. …

Fidarestat

Experimental
Matched Synonyms: … (S,S)-fidarestat …

(S)-Rolipram

A phosphodiesterase inhibitor with antidepressant properties. [PubChem]
Experimental
Matched Synonyms: … S-rolipram ... (S)-(+)-rolipram …
Matched Name: … (S)-Rolipram …

Arginine aspartate

Experimental
Matched Synonyms: … L-Arginine-L-aspartate ... Arginine L-aspartate ... L-Arginine aspartate …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Desoxycorticosterone acetate

Approved
Matched Synonyms: … 11-deoxycorticosterone acetate …
Matched Iupac: … 2-[(1S,3aS,3bS,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

YT-001

Investigational
Matched Synonyms: … N-myristoylated -Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr ... L-Threonine, N-(1-oxotetradecyl)-L-α-glutamyl-L-alanyl-L-valyl-L-seryl-L-leucyl-L-lysyl-L-prolyl- …

Dextroamphetamine

Dextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Approved
Illicit
Matched Synonyms: … (+)-(S)-amphetamine ... (S)-amphetamine ... (S)-(+)-amphetamine …
Matched Mixtures name: … Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CII ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CII ... Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CII …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Act Dextroamphetamine SR ... Apo-dextroamphetamine SR ... Dexedrine Spansule Src 15mg …

Azatadine

Antihistamines such as azatadine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.
Approved
Matched Synonyms: … 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Description: … those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and ... thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release …

NB-124 sulfate

Investigational
Matched Synonyms: … 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-a-l-talofuranosyl)- paromamine sulfate ... 6'-(r)-methyl-5-o-(5-amino-5,6-dideoxy-alpha-l-talofuranosyl)-paromamine sulfate …

IDN-7314

Investigational
Matched Synonyms: … (s)-3-((s)-2-(2-((2,6-difluorophenyl)amino)-2-oxoacetamido)propanamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy ... L-alaninamide, n-(2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy ... 2,6-difluorophenyl)-2-oxoglycyl-n-((1s)-1-(carboxymethyl)-2-oxo-3-(2,3,5,6-tetrafluorophenoxy)propyl)-l-alaninamide …

RWJ-800088

RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.
Investigational
Matched Synonyms: … RWJ-800088 (PEGYLATED THROMBOPOIETIN (TPO)-MIMETIC PEPTIDE) ... METHOXYPOLYETHYLENEGLYCOL20000-PROPIONYL-L-ISOLEUCYL-L-GLUTAMYL-GLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-L ... -GLUTAMYLGLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-LEUCYL-L-ALANYL-L-ALANY …
Matched Name: … RWJ-800088 …
Matched Description: … RWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Insulin glargine

Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched International brands: … Lantus R …
Matched Description: … addition of two arginines to the C-terminus (positions B31 and 32) of the B-chain. ... climb to dangerously high levels and can result in symptoms such as fatigue, headache, blurred vision ... Due to its duration of action, Lantus is considered "basal insulin" as it provides low concentrations …
Matched Mixtures name: … SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM ... SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM ... SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEM …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … GLARIN 100 U/ML SC KULLANIM IÇIN ENJEKSIYONLUK ÇÖZELTI IÇEREN KARTUŞ, 5 ADET ... TOUJEO 300 U/ML SOLOSTAR SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKSİYON KALEMİ, 3 ADET ... TOUJEO 300 U/ML SOLOSTAR SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKSİYON KALEMİ, 5 ADET …

Solnatide

Solnatide has been used in trials studying the treatment of Acute Lung Injury.
Investigational
Matched Synonyms: … Cys-gly-gln-arg-glu-thr-pro-glu-gly-ala-glu-ala-lys-pro-trp-tyr-cys cyclic (1->17)-disulfide ... L-Cysteine, L-cysteinylglycyl-L-glutaminyl-L-arginyl-L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-glutamylglycyl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-lysyl-L-prolyl-L-tryptophyl-L-tyrosyl …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Bemcentinib

Bemcentinib has been investigated for the treatment of Non-Small Cell Lung Cancer.
Investigational
Matched Synonyms: … (S)-1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-(7-(pyrrolidin-1-yl)- 6,7,8,9-tetrahydro …

WT-1 A1

Investigational
Matched Synonyms: … L-leucine, l-tyrosyl-l-methionyl-l-phenylalanyl-l-prolyl-l-asparaginyl-l-alanyl-l-prolyl-l-tyrosyl- ... Tyr-met-phe-pro-asn-ala-pro-tyr-leu …

Zilucoplan

Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses. On October 17, 2023, zilucoplan gained its first FDA approval for the treatment of...
Approved
Matched Synonyms: … N2-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA.-GLUTAMYL-L-ARGINYL-L-PHENYLALANYL-L-.ALPHA. ... -ASPARTYL-3-METHYL-L-VALYL-L-TYROSYL-3-(1H-PYRROLO(2,3-B)PYRIDIN-3-YL)-L-ALANYL-L-.ALPHA. ... -HYDROXY-, 15-ETHER WITH N-ACETYL-L-LYSYL-L-VALYL-L-.ALPHA. …
Matched Iupac: … (2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{1-[(2S,5S,8S,11S,14S,22S)-11 …
Matched Description: … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …

Linzagolix

Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix. Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Description: … , and reproductive dysfunction. ... [A253642,A253647] It is similar to other GnRH receptor antagonists like [cetrorelix], [relugolix], and ... Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with …
Matched Salts name: … Linzagolix choline …
Matched Categories: … Sex Hormones and Insulins ... Pituitary and Hypothalamic Hormones and Analogues …
Matched Products: … KLH-2109 Choline …

Aripiprazole

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs …
Matched Products: … Abilify Maintena 400 mg powder and solvent for prolonged-release suspension for injection ... ABILIFY MAINTENA POWDER AND SOLVENT FOR PROLONGED RELEASE SUSPENSION FOR INJECTION 400 MG ... ARIPIPRAZOLE ABILIFY(R) TABLETS 5 MG …

Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen

Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group C capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Products: … NeisVac-C Injektionssuspension in einer Fertigspritze …

Allovectin-7

Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and beta-2 microglobulin. It was discontinued after it failed to improve the objective response rate or overall survival versus first-line chemotherapy in malignant melanoma.
Investigational
Matched Synonyms: … Allovectin-7(r) …
Matched Description: … Allovectin-7 or allovectin-7(r) is a lipid complex that contains the DNA sequences encoding HLA-B7 and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Desogestrel

Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Synonyms: … 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol …
Matched Iupac: … 10H,11H,11aH-cyclopenta[a]phenanthren-1-ol ... (1R,3aS,3bS,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH, …
Matched Description: … [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent ... in nortestosterone can enhance the biological activity. ... family which was largely used in Europe before being approved in the US and Canada. …
Matched Mixtures name: … Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol and Ethinyl Estradiol ... Desogestrel and Ethinyl Estradiol …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... desogestrel and estrogen ... desogestrel and ethinylestradiol ... desogestrel and ethinylestradiol …

Droxidopa

Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Synonyms: … L-DOPS ... L-Dihydroxyphenylserine ... L-threo-dihydroxyphenylserine …
Matched Description: … Though L-DOPS has been used in Japan and Southeast Asia already for some time, it is also currently in ... Chelsea Therapeutics obtained orphan drug status (ODS) for L-DOPS in the U.S. for NOH, and that of which ... associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Amino Acids, Peptides, and Proteins …

(4R)-limonene

Limonene is common in cosmetic products. As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery.
Investigational
Matched Synonyms: … (+)-(R)-Limonene ... (R)-(+)-limonene ... (R)-p-mentha-1,8-diene …
Matched Description: … the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and ... some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant in perfumery …

LSTA1

Investigational
Matched Synonyms: … L-cysteine, l-cysteinyl-l-arginylglycyl-l-.alpha.-aspartyl-l-lysylglycyl-l-prolyl-l-.alpha. …

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL ... L-TYROSINE, L-CYSTEINYL-L-CYSTEINYL-L-.ALPHA. ... (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE …
Matched Description: … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... (G-CC) agonist. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Guanylate Cyclase-C Agonist ... Guanylyl Cyclase C Agonists …
Displaying drugs 776 - 800 of 2125 in total