Displaying drugs 776 - 800 of 2661 in total
Dexrazoxane
An antimitotic agent with immunosuppressive properties. Dexrazoxane, the (+)-enantiomorph of razoxane, provides cardioprotection against anthracycline toxicity. It appears to inhibit formation of a toxic iron-anthracycline complex. [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the prevention or reduction in the incidence and...
Approved
Withdrawn
Matched Description: … prevention or reduction in the incidence and severity of anthracycline-induced cardiomyopathy. ... [PubChem]
The Food and Drug Administration has designated dexrazoxane as an orphan drug for use in the …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Matched Salts name: … Dexrazoxane hydrochloride …
Matched Products: … Dexrazoxane Hydrochloride …
Oteracil
Oteracil is an adjunct to antineoplastic therapy, used to reduce the toxic side effects associated with chemotherapy. Approved by the European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with DB09257 and DB09256 within the commercially available product "Teysuno". The main active ingredient in Teysuno is DB09256,...
Approved
Matched Synonyms: … Oxonic Acid ... 5-azaorotic acid ... Allantoxanic acid …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Matched Iupac: … 4,6-dioxo-1,4,5,6-tetrahydro-1,3,5-triazine-2-carboxylic acid …
Matched Description: … European Medicines Agency (EMA) in March 2011, Oteracil is available in combination with [DB09257] and ... By mimicking a class of compounds called "pyrimidines" that are essential components of RNA and DNA, ... 5-FU is able to insert itself into strands of DNA and RNA, thereby halting the replication process necessary …
Phenylbutyric acid
Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Synonyms: … Benzenebutyric acid ... 4-phenylbutyric acid ... 4-Phenyl-n-butyric acid …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Matched Name: … Phenylbutyric acid …
Matched Iupac: … 4-phenylbutanoic acid …
Matched Description: … Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... sodium phenylbutyrate and ursodoxicoltaurine ... Various Alimentary Tract and Metabolism Products …
Duloxetine
Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder. It has since received approval for a...
Approved
Matched Description: … [label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. ... Duloxetine is a dual serotonin and norepinephrine reuptake inhibitor. ... Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more. …
Matched Salts name: … Duloxetine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Duloxetine hydrochloride ... Duloxetine Hydrochloride ... Duloxetine Hydrochloride 20 mg …
Matched Salts name: … Duloxetine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Duloxetine hydrochloride ... Duloxetine Hydrochloride ... Duloxetine Hydrochloride 20 mg …
Melphalan
Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Iupac: … (2S)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoic acid …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …
Cyclobenzaprine
Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …
Nitarsone
Nitarsone is an organoarsenic compound. It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing blackhead disease. It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.
Vet approved
Matched Synonyms: … (p-nitrophenyl)arsonic acid ... 4-nitrobenzenearsonic acid ... 4-nitrophenylarsonic acid …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Matched Iupac: … (4-nitrophenyl)arsonic acid …
Matched Description: … It is used as an additive in poultry feed to improve weight gain and feed efficiency, while preventing …
Isoferulic acid
Experimental
Matched Synonyms: … Hesperetic acid ... Isoferulic acid …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … Isoferulic acid …
Matched Iupac: … (2E)-3-(3-hydroxy-4-methoxyphenyl)prop-2-enoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Madecassic acid
Experimental
Matched Synonyms: … Brahmic acid ... 6β-hydroxyasiatic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Matched Name: … Madecassic acid …
Matched Iupac: … 9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylic acid …
Venlafaxine
Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). Its active metabolite, desvenlafaxine, works by blocking the reuptake of serotonin and norepinephrine, which are key neurotransmitters in mood regulation. Venlafaxine is officially approved to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and...
Approved
Matched Description: … Venlafaxine is an antidepressant and a serotonin and norepinephrine reuptake inhibitor (SNRI). ... Its active metabolite, [desvenlafaxine], works by blocking the reuptake of serotonin and norepinephrine ... treat major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder, and …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …
Matched Salts name: … Venlafaxine hydrochloride …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …
Matched Products: … Venlafaxine hydrochloride ... Venlafaxine Hydrochloride ... Venlafaxine Hydrochloride ER …
Cyclohexanepropanoic acid
Experimental
Matched Synonyms: … 3-Cyclohexanepropionic acid ... 3-Cyclohexylpropanoic acid ... 3-Cyclohexylpropionic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Matched Name: … Cyclohexanepropanoic acid …
Matched Iupac: … 3-cyclohexylpropanoic acid …
Salicylamide O-acetic acid
Experimental
Matched Synonyms: … Salamidacetic acid ... Salicylamide-2-acetic acid ... 2-Carbamoylphenoxyacetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Matched Name: … Salicylamide O-acetic acid …
Matched Iupac: … 2-(2-carbamoylphenoxy)acetic acid …
Caprylhydroxamic acid
Experimental
Matched Synonyms: … Caprylohydroxamic acid ... Octanohydroxamic acid ... Octanoylhydroxamic acid …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
Matched Name: … Caprylhydroxamic acid …
Matched Categories: … Hydroxy Acids ... Carboxylic Acids …
3-phenylpropionic acid
Experimental
Matched Synonyms: … Hydrocinnamic acid ... 3-phenyl-propionic acid ... 3-phenylpropanoic acid …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
Matched Name: … 3-phenylpropionic acid …
Matched Iupac: … 3-phenylpropanoic acid …
Matched Categories: … Carboxylic Acids ... Acids, Carbocyclic …
L-2-aminopimelic acid
Experimental
Matched Synonyms: … 2-Aminopimelic acid ... L-α-aminopimelic acid ... L-alpha-Aminopimelic acid …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … L-2-aminopimelic acid …
Matched Iupac: … (2S)-2-aminoheptanedioic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Pidolic acid
Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various chemical pathways [A32991, L2729]. Elevations of the acid in blood levels may be associated with problems of glutamine or glutathione metabolism...
Approved
Investigational
Matched Synonyms: … Glutimic acid ... Pidolic acid ... Pyroglutamic acid …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Salts name: … Zinc pidolate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
Matched Name: … Pidolic acid …
Matched Iupac: … (2S)-5-oxopyrrolidine-2-carboxylic acid …
Matched Description: … Pidolic acid, in general, is found in large quantities in brain tissue and other tissues in bound form ... or non-enzymatically and participates as a biological intermediate with unique pharmacodynamics in various ... Pidolic acid is a naturally occurring but little-studied amino acid derivative that can be formed enzymatically …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Salts name: … Zinc pidolate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids ... Imino Acids …
Terbinafine
Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal.[L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (also called squalene epoxidase), an enzyme that is part of the fungal cell...
Approved
Investigational
Vet approved
Matched Description: … [L9065,L9068] It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues ... Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. ... [A1279,A1281,L9068]
Terbinafine hydrochloride was granted FDA approval on 30 December 1992. …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Salts name: … Terbinafine hydrochloride …
Matched Products: … Terbinafine Hydrochloride ... Terbinafine Hydochloride ... GoodSense Terbinafine Hydrochloride …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Salts name: … Terbinafine hydrochloride …
Matched Products: … Terbinafine Hydrochloride ... Terbinafine Hydochloride ... GoodSense Terbinafine Hydrochloride …
L-tartaric acid
Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics, and is a dihydroxyl derivative of succinic acid.
Experimental
Matched Synonyms: … (+)-Tartaric acid ... Tartaric acid ... (+)-L-tartaric acid …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … , and is a dihydroxyl derivative of succinic acid. ... in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … L-tartaric acid …
Matched Iupac: … (2R,3R)-2,3-dihydroxybutanedioic acid …
Matched Description: … , and is a dihydroxyl derivative of succinic acid. ... in grapes.Tartaric is an alpha-hydroxy-carboxylic acid, is diprotic and aldaric in acid characteristics ... Tartaric acid is a white crystalline organic acid that occurs naturally in many plants, most notably …
Matched Categories: … Acids, Acyclic ... Sugar Acids ... Hydroxy Acids ... Carboxylic Acids ... Dicarboxylic Acids …
(S)-3-phenyllactic acid
Experimental
Matched Synonyms: … L-3-phenyllactic acid ... L-β-phenyllactic acid ... L-(−)-3-phenyllactic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Matched Name: … (S)-3-phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-3-phenylpropanoic acid …
Norvaline
Norvaline is an isomer of the more common amino acid valine.
Experimental
Matched Synonyms: … 2-Aminovaleric acid ... 2-Aminopentanoic acid ... L-2-Aminovaleric acid …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Matched Iupac: … (2S)-2-aminopentanoic acid …
Matched Description: … Norvaline is an isomer of the more common amino acid valine. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Branched-Chain …
Oxaloacetic acid
Investigational
Matched Synonyms: … Oxalacetic acid ... Ketosuccinic acid ... Oxosuccinic acid …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Name: … Oxaloacetic acid …
Matched Iupac: … 2-oxobutanedioic acid …
Matched Categories: … Keto Acids ... Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
alpha-Linolenic acid
Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. It is a component of many common vegetable oils and is important to human nutrition.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Linolenic acid ... α-linolenic acid ... (9,12,15)-linolenic acid …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Matched Name: … alpha-Linolenic acid …
Matched Iupac: … (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid …
Matched Description: … It is a component of many common vegetable oils and is important to human nutrition. ... Alpha-linolenic acid (ALA) is a polyunsaturated omega-3 fatty acid. …
Matched Categories: … Fatty Acids ... Linolenic Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Essential ... Fatty Acids, Unsaturated …
Nedometinib
Investigational
Matched Synonyms: … 2-((2-fluoro-4-iodophenyl)amino)-n-(2-hydroxyethoxy)-1-methyl-1h-pyrrolo(2,3-b)pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
Matched Iupac: … 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxamide …
AZD2066
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine …
Iodamide
Iodamide is a contrast medium molecule that is no longer marketed in the United States.
Withdrawn
Matched Synonyms: … Ametriiodic acid ... Ametriodinic acid ... Ametriiodinic acid …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Matched Iupac: … 3-acetamido-5-(acetamidomethyl)-2,4,6-triiodobenzoic acid …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Displaying drugs 776 - 800 of 2661 in total