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Displaying drugs 8001 - 8025 of 11649 in total
Ramoplanin is a novel glycolipodepsipeptide antibiotic under development for the treatment of CDAD.
Investigational
Matched Iupac: … ,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-{[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2- ... (4-hydroxyphenyl)-6-methyl-9-(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-hexadecaoxo ... -1-oxa-4,7,10,13,16,19,22,25,28,31,34,37,40,43,46-pentadecaazacyclononatetracontan-48-yl]-2-[(2Z,4Z)- ... yl]oxy}oxan-2-yl]oxy}phenyl)-18,39-bis[(1R)-1-hydroxyethyl]-30-[(1S)-1-hydroxyethyl]-15,33,36,45-tetrakis …
Trabodenoson has been used in trials studying the treatment of Ocular Hypertension (OHT) and Primary Open-Angle Glaucoma (POAG).
Investigational
Matched Iupac: … [(2R,3S,4R,5R)-5-[6-(cyclopentylamino)-9H-purin-9-yl]-3,4-dihydroxyoxolan-2-yl]methyl nitrate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … 2-(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-yl)acetic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Levonadifloxacin is under investigation in clinical trial NCT03405064 (Comparative Study of Levonadifloxacin (IV and Oral) With Linezolid (IV and Oral) in Acute Bacterial Skin and Skin Structure Infections (ABSSSI)).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Naphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
Investigational
Matched Iupac: … 2-[(tert-butylamino)methyl]-4-[(7-chloroquinolin-4-yl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Rotigaptide is under investigation for the basic science of Heart Disease and Vascular Disease.
Investigational
Matched Iupac: … (2R)-N-(carbamoylmethyl)-2-(2-{[(2R,4S)-1-[(2R)-1-[(2R)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]pyrrolidine ... -2-carbonyl]-4-hydroxypyrrolidin-2-yl]formamido}acetamido)propanamide …
JTK-853 has been used in trials studying the treatment of Hepatitis C Virus Infection, Response to Therapy of.
Investigational
Matched Iupac: … }-1-[4-(trifluoromethyl)benzenesulfonyl]piperazine-2-carboxamide ... (2R)-4-{5-cyclopropyl-[1,3]thiazolo[4,5-d]pyrimidin-2-yl}-N-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl …
An antibiotic purine ribonucleoside that readily substitutes for adenosine in the biological system, but its incorporation into DNA and RNA has an inhibitory effect on the metabolism of these nucleic acids.
Experimental
Matched Iupac: … (2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bunazosin has been used in trials studying the treatment of High Blood Pressure.
Investigational
Matched Iupac: … 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-1,4-diazepan-1-yl]butan-1-one …
Matched Salts cas: … 52712-76-2
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Surufatinib is under investigation in clinical trial NCT02588170 (Phase III Study of Surufatinib in Treating Advanced Extrapancreatic Neuroendocrine Tumors).
Investigational
Matched Iupac: … N-[2-(dimethylamino)ethyl]-1-[3-({4-[(2-methyl-1H-indol-5-yl)oxy]pyrimidin-2-yl}amino)phenyl]methanesulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Investigational
Investigational
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Experimental
Illicit
Matched Iupac: … (1R,2R,6S,14R,15R,19R)-3-(cyclopropylmethyl)-19-(2-hydroxypropan-2-yl)-15-methoxy-13-oxa-3-azahexacyclo …
Vapitadine is an antihistamine that Barrier Therapeutics is developing as a treatment for allergic reactions of the skin, such as those associated with hives and for the itch associated with atopic dermatitis. An advantage of vapitadine over other antihistamines may be the absence of the sedation, even at high doses.
Investigational
Experimental
Matched Iupac: … N-{4-[(diaminomethylidene)amino]butyl}-2-(1,3-thiazol-4-yl)-1,3-thiazole-4-carboxamide …
Experimental
Experimental
Matched Iupac: … -3-[(2-{[2-(tetradecanoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]propoxy]phosphoryl}oxy)phosphoryl]oxy ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … -3-{[2-({2-[(3-oxobutanoyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl ... {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-2,2-dimethyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tocladesine has been used in trials studying the treatment of Colorectal Cancer and Multiple Myeloma and Plasma Cell Neoplasm.
Investigational
Matched Iupac: … (6-amino-8-chloro-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-2lambda5-furo[3,2-d][1,3,2]dioxaphosphinin-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Chromanol has been used in trials studying the treatment of Prostate Cancer.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … 2-{[(Z)-[(2-amino-1,3-thiazol-4-yl)({[(2S,3S)-2-[(carbamoyloxy)methyl]-4-oxo-1-sulfoazetidin-3-yl]carbamoyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Experimental
Matched Iupac: … 12-bromo-3-methyl-9-(pyridin-2-yl)-2,4,5,8-tetraazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Ellipticine is a potent antineoplastic agent.
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 8001 - 8025 of 11649 in total