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Displaying drugs 8301 - 8325 of 11037 in total

Phosphonotyrosine

An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. [PubChem]
Experimental
Matched Iupac: … (2S)-2-amino-3-[4-(phosphonooxy)phenyl]propanoic acid …

Ragaglitazar

Investigational
Matched Iupac: … (2R)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoic acid …

p-Benzoyl-L-phenylalanine

Experimental
Matched Iupac: … (2S)-2-amino-3-(4-benzoylphenyl)propanoic acid …

Medical Cannabis

The use of the plant species Cannabis sativa and Cannabis indica, popularly known as marijuana, has gained popularity in recent years for the management of a wide variety of medical conditions as a wave of legalization in North America has changed public and medical opinion on its use. Consequently, an...
Experimental
Investigational
Matched Description: … mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 ... There is further evidence that CBD also activates 5-HT1A serotonergic and TRPV1–2 vanilloid receptors ... demonstrates its effects through weak partial agonist activity at Cannabinoid-1 (CB1R) and Cannabinoid-2 …

Allisartan isoproxil

Allisartan isoproxil is under investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 Diabetes).
Investigational
Matched Synonyms: … 1H-IMIDAZOLE-5-CARBOXYLIC ACID, 2-BUTYL-4-CHLORO-1-((2'-(2H-TETRAZOL-5-YL)(1,1'-BIPHENYL)-4-YL)METHYL …
Matched Description: … investigation in clinical trial NCT03264352 (Intervention for High-normal Blood Pressure in Adults With Type 2 …

4-hydroxybenzoyl-CoA

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-[(2-{[2-(4 ... hydroxybenzoylsulfanyl)ethyl]carbamoyl}ethyl)carbamoyl]-2,2-dimethylpropoxy]phosphoryl}oxy)phosphoryl]oxy}methyl)oxolan-3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

4-(N,N-Dimethylamino)cinnamoyl-CoA

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-({[({[(3R)-3-({2-[(2-{[(2E)-3-[4-(dimethylamino)phenyl]prop ... -2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)-3-hydroxy-2,2-dimethylpropoxy](hydroxy)phosphoryl} ... oxy)(hydroxy)phosphoryl]oxy}methyl)-4-hydroxyoxolan-3-yl]oxy}phosphonic acid …

Deacetoxyvinzolidine

Experimental
Matched Iupac: … -2',4',6',13'-tetraen-4'-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca ... dioxo-8',16'-diazaspiro[1,4-oxazolidine-2,10'-pentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadecane] ... methyl (13S,15R,17S)-13-[(1'R,2R,9'R,12'R,19'S)-4-(2-chloroethyl)-12'-ethyl-5'-methoxy-8'-methyl-3,5- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Golotimod

SCV-07 (g -D-glutamyl-L-tryptophan) is a novel synthetic dipeptide that acts broadly on the Toll-like receptor pathway. It has been shown to stimulate T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 and INF-g production. Due to this preferential activation of Th1 cytokine production, SCV-07 may show utility in...
Investigational
Matched Iupac: … (2R)-2-amino-4-{[(1S)-1-carboxy-2-(1H-indol-3-yl)ethyl]carbamoyl}butanoic acid …
Matched Description: … T-lymphocyte differentiation, macrocytic phagocytosis, and specific immune responses, and enhance IL-2 …

Lixivaptan

Investigational
Matched Iupac: … 5-fluoro-2-methylbenzamide ... N-(3-chloro-4-{3,9-diazatricyclo[8.4.0.0^{3,7}]tetradeca-1(10),4,6,11,13-pentaene-9-carbonyl}phenyl)- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Relamorelin

Relamorelin has been investigated for the treatment and basic science of Gastroparesis, Gastric Motility, Diabetes Mellitus, Parkinson's Disease, and Chronic Constipation, among others.
Investigational
Matched Iupac: … 4-[(2S)-2-[(2R)-2-[(2R)-3-(1-benzothiophen-3-yl)-2-[(piperidin-4-yl)formamido]propanamido]-3-(1H-indol ... -3-yl)propanamido]-3-phenylpropanamido]piperidine-4-carboxamide …

alpha-Methylleucine

Experimental
Matched Synonyms: … (S)-2-Methylleucine ... 2-Methyl-L-leucine …
Matched Iupac: … (2S)-2-amino-2,4-dimethylpentanoic acid …

Octyldodecanol

Experimental
Matched Synonyms: … 2-Octyl dodecanol ... 2-Octyl-1-dodecanol ... 2-Octyldodecyl alcohol …
Matched Iupac: … 2-octyldodecan-1-ol …

2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline

Experimental
Matched Name: … 2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline …

(6,7-Difluoro-Quinazolin-4-Yl)-(1-Methyl-2,2-Diphenyl-Ethyl)-Amine

Experimental
Matched Iupac: … N-[(2S)-1,1-diphenylpropan-2-yl]-6,7-difluoroquinazolin-4-amine …

Epibatidine

Experimental
Matched Iupac: … (1R,2R,4S)-2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane …

Nepadutant

Nepadutant has been used in trials studying the treatment of Colic, Infantile Colic, and Infantile Functional Gastrointestinal Disorders.
Investigational
Matched Iupac: … 2-[(1S,4S,7S,10S,13S,16S)-4-benzyl-7-[(1H-indol-3-yl)methyl]-16-(2-methylpropyl)-3,6,9,12,15,18,21-heptaoxo ... -6-(hydroxymethyl)oxan-2-yl]acetamide ... -2,5,8,11,14,17,20-heptaazabicyclo[8.8.4]docosan-13-yl]-N-[(2R,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy …

LTX-109

LTX-109 has been investigated for the treatment of Atopic Dermatitis, Mild Eczema/Dermatoses, and Gram-positive, Skin Infections.
Investigational
Matched Iupac: … (2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propanamido ... ]-5-carbamimidamido-N-(2-phenylethyl)pentanamide …

Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine

Experimental
Matched Name: … Trans-6-(2-Phenylcyclopropyl)-Naphthalene-2-Carboxamidine …
Matched Iupac: … 6-[(1R,2R)-2-phenylcyclopropyl]naphthalene-2-carboximidamide …

N-[amino(imino)methyl]-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide

Experimental
Matched Name: … N-[amino(imino)methyl]-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide …
Matched Iupac: … N-carbamimidoyl-2-(2,5-diphenyl-1H-pyrrol-1-yl)acetamide …

N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine

Experimental
Matched Name: … N-1H-indazol-5-yl-2-(6-methylpyridin-2-yl)quinazolin-4-amine …
Matched Iupac: … N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine …

2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM

Experimental
Matched Name: … 2-[(1S)-1-BENZYL-2-SULFANYLETHYL]-1H-IMIDAZO[4,5-C]PYRIDIN-5-IUM …
Matched Iupac: … 2-[(2S)-1-phenyl-3-sulfanylpropan-2-yl]-1H-imidazo[4,5-c]pyridin-5-ium …

Camptothecin

Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
Matched Iupac: … (19S)-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1(21 …

Evatanepag

Evatanepag has been used in trials studying the treatment of Tibial Fractures.
Investigational
Matched Iupac: … 2-[3-({N-[(4-tert-butylphenyl)methyl]pyridine-3-sulfonamido}methyl)phenoxy]acetic acid …

2-Deoxy-alpha-D-galactopyranose

Experimental
Matched Synonyms: … 2-deoxy-beta-D-galactose ... 2-Deoxy-α-D-lyxo-hexopyranose ... 2-Deoxy-alpha-D-lyxo-hexopyranose …
Matched Name: … 2-Deoxy-alpha-D-galactopyranose …
Displaying drugs 8301 - 8325 of 11037 in total