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Displaying drugs 8326 - 8350 of 11806 in total

LY231514 tetra glu

Experimental
Matched Iupac: … 2-[(4S)-4-[(4S)-4-[(4S)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H-pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido …

(4S,5S)-1,2-dithiane-4,5-diol

Experimental

25-desacetylrifapentine

25-desacetylrifapentine is under investigation in clinical trial NCT00023387 (TBTC Study 25PK: Intensive Pharmacokinetic Study of Three Doses of Rifapentine and 25-Desacetyl Rifapentine).
Investigational

Dianhydrogalactitol

Dianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
Investigational
Matched Iupac: … (1R,2S)-1-[(2R)-oxiran-2-yl]-2-[(2S)-oxiran-2-yl]ethane-1,2-diol …

Erythritol

Erythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
Experimental

BQ-788

Investigational
Matched Iupac: … sodium (2R)-2-[(2R)-2-[(2S)-2-{[(2R,6S)-2,6-dimethylpiperidine-1-carbonyl]amino}-4,4-dimethylpentanamido …

OptPA

Optimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.
Investigational

Creatinine

Creatinine has been used in trials studying the treatment of Amyotrophic Lateral Sclerosis.
Investigational
Matched Iupac: … 2-imino-1-methylimidazolidin-4-one …

BMS-488043

BMS-488043 has been investigated as an anti-HIV agent.
Investigational
Matched Iupac: … 1-(4-benzoylpiperazin-1-yl)-2-{4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl}ethane-1,2-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tocopherylquinone

Experimental
Investigational
Matched Iupac: … 2-[(3R,7R,11R)-3-hydroxy-3,7,11,15-tetramethylhexadecyl]-3,5,6-trimethylcyclohexa-2,5-diene-1,4-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Buthiazide

Experimental
Matched Iupac: … 6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

GC-376 free acid

GC-376 is a 3C-like protease (3CLpro or Mpro) inhibitor that stops the cleavage and activation of functional viral proteins required for replication and transcription in host cells . The compound is known as a direct acting antiviral (DAA) for coronaviruses, and was initially developed using structure-guided design to combat MERS-Cov...
Experimental
Matched Iupac: … (2S)-2-[(2S)-2-{[(benzyloxy)carbonyl]amino}-4-methylpentanamido]-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane …
Matched Description: … A prodrug of [GC-373], GC-376 has recently been used to test inhibition of SARS-Cov-2 Mpro …

O2-Sulfo-Glucuronic Acid

Experimental
Matched Iupac: … (2R,3S,4S,5R,6R)-3,4,6-trihydroxy-5-(sulfooxy)oxane-2-carboxylic acid …

2,4,6-Triaminoquinazoline

Experimental

2,6-diaminoquinazolin-4-ol

Experimental

SNX-5422

SNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.
Investigational
Matched Iupac: … phenyl}amino)cyclohexyl 2-aminoacetate ... (1r,4r)-4-({2-carbamoyl-5-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl] …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tricetin

Experimental
Matched Iupac: … 5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline

Potent reversible inhibitor of phenylethanolamine N-methyltransferase.
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Orantinib

Orantinib has been used in trials studying the treatment of Lung Cancer, Breast Cancer, Kidney Cancer, Gastric Cancer, and Prostate Cancer, among others.
Investigational
Matched Iupac: … 3-(2,4-dimethyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Indiplon

Indiplon has been used in trials studying the treatment of Insomnia and Depression.
Investigational
Matched Iupac: … N-methyl-N-{3-[3-(thiophene-2-carbonyl)pyrazolo[1,5-a]pyrimidin-7-yl]phenyl}acetamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Butylphthalide

Butylphthalide has been used in trials studying the prevention of Restenosis.
Investigational
Matched Iupac: … 3-butyl-1,3-dihydro-2-benzofuran-1-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bentracimab

Bentracimab is under investigation in clinical trial NCT04286438 (Bentracimab (PB2452) in Ticagrelor-treated Patients With Uncontrolled Major or Life-threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure).
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …

6-hydroxy-FAD

Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}({[hydroxy({[(2R,3S,4S)-2,3,4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Orbifloxacin

Orbifloxacin is a fluoroquinolone antibiotic. It is marketed by Schering-Plough Animal Health and approved for certain infections in dogs.
Vet approved
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sarafloxacin

Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Vet approved
Withdrawn
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 8326 - 8350 of 11806 in total