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Displaying drugs 8376 - 8400 of 11301 in total

Zanidatamab

According to Zymeworks, "ZW25 is a bispecific antibody that can simultaneously bind two non-overlapping epitopes, known as biparatopic binding, of HER2 resulting in dual HER2 signal blockade, increased binding and removal of HER2 protein from the cell surface, and potent effector function. These combined mechanisms of action have led to...
Investigational
Matched Synonyms: … KINASE ERBB-2, EGFR2, HER2, HER-2, P185C-ERBB2, NEU, CD340)), HUMANIZED MONOCLONAL ANTIBODY, BIPARATOPIC ... IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS ERBB2 (EPIDERMAL GROWTH FACTOR RECEPTOR 2, RECEPTOR TYROSINEPROTEIN …

Ginsenoside Rg3

Ginsenoside Rg3 is under investigation in clinical trial NCT01757366 (Safety and Efficacy of Ginsenoside Rg3 in Combination With First-line Chemotherapy in Advanced Gastric Cancer).
Investigational
Matched Synonyms: … .)-12,20-dihydroxydammar-24-en-3-yl 2-o-.beta.-d-glucopyranosyl- ... -d-glucopyranosyl-(1->2)-.beta.-d-glucopyranosyldammar-24-ene-3.beta.,12.beta.,20s-triol …

Ivuxolimab

Ivuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Investigational

2-Oxobutanoic Acid

Experimental
Matched Name: … 2-Oxobutanoic Acid …
Matched Iupac: … 2-oxobutanoic acid …

LY2140023

LY2140023 is an investigational drug from Lilly, which is being developed as a new treatment option for schizophrenia. LY2140023 is an oral "prodrug," meaning it is devoid of intrinsic biological activity and, once administered, is metabolized to provide the active mGlu2/3 receptor agonist called LY404039. Most currently approved antipsychotic medications...
Investigational

Evenamide

Investigational
Matched Synonyms: … 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethylacetamide ... Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethyl- …

(R)-Propafenone

Propafenone, (r)- is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
Investigational
Matched Synonyms: … 1-propanone, 1-(2-((2r)-2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl- …

6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE

Experimental
Matched Name: … 6-[2-(3'-METHOXYBIPHENYL-3-YL)ETHYL]PYRIDIN-2-AMINE …
Matched Iupac: … 6-(2-{3'-methoxy-[1,1'-biphenyl]-3-yl}ethyl)pyridin-2-amine …

Barnidipine

Barnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the smooth muscle cells in the vascular wall and selectivity against cardiovascular L-type calcium channels . Barnidipine...
Experimental
Matched Iupac: … 3-(3S)-1-benzylpyrrolidin-3-yl 5-methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … hypertension, the antihypertensive response from barnidipine treatment was maintained after a 1-year and 2- …

Lirentelimab

Lirentelimab is under investigation in clinical trial NCT04856891 (A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS SIALIC ACID-BINDING IG-LIKE LECTIN 8 (SIALOADHESIN FAMILY MEMBER 2, ... SIGLEC-8, SAF-2))HUMANIZED MOUSE MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-450) (VH (HOMO SAPIENS IGHV3 …

(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID

Experimental
Matched Name: … (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-methylpropyl](hydroxy)phosphoryl …

Carbon black

Produced by the incomplete combustion of hydrocarbons, carbon black is an insoluble pigment with demonstrated adverse effects on pulmonary function. Upon inhalation, carbon black has been reported to trigger an inflammatory response in the lung tissue and has been linked to carcinogenicity.[A263406, A263411, A263416]
Investigational
Matched Synonyms: … BLACK 2 ... D&C black no. 2 ... DC BLACK NO. 2 …

(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID

Experimental
Matched Name: … (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-benzenesulfonamido-2-methylpropyl](hydroxy)phosphoryl}propanoic …

N-(2-Aminoethyl)-1-aziridineethanamine

First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease and its activity against Severe Acute Respiratory Syndrome (SARS).
Experimental
Matched Synonyms: … N-(2-((2-Aminoethyl)amino)ethyl)aziridine ... N-(2-aminoethyl)-1 aziridine-ethanamine …
Matched Name: … N-(2-Aminoethyl)-1-aziridineethanamine …
Matched Iupac: … (2-aminoethyl)[2-(aziridin-1-yl)ethyl]amine …
Matched Description: … First described in the literature in 2004, N-(2-Aminoethyl)-1-aziridineethanamine is an experimental ... angiotensin converting enzyme 2 inhibitor investigated for its use in treating cardiovascular disease …

N-acetyl-alpha-D-glucosamine

The N-acetyl derivative of glucosamine.
Experimental
Matched Synonyms: … 2-(acetylamino)-2-deoxy-A-D-glucopyranose ... 2-(acetylamino)-2-deoxy-α-D-glucopyranose …

Denenicokin

Denenicokin is under investigation in clinical trial NCT01152788 (Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma).
Investigational

N-T-Butylhydroxylamine

Investigational
Matched Synonyms: … 2-hydroxylamino-2-methylpropane ... N-hydroxy-2-methyl-2-propanamine …

Darleukin

Investigational

2-Bromoacetyl Group

Experimental
Matched Name: … 2-Bromoacetyl Group …
Matched Iupac: … 2-bromoacetic acid …

2-(Sec-Butyl)Thiazole

Experimental
Matched Name: … 2-(Sec-Butyl)Thiazole …
Matched Iupac: … 2-[(2R)-butan-2-yl]-1,3-thiazole …

2-Iminiopropanoate

Experimental
Matched Name: … 2-Iminiopropanoate …
Matched Iupac: … 2-iminiumylpropanoate …

1-Methyl-2-quinolone

Experimental
Matched Name: … 1-Methyl-2-quinolone …
Matched Iupac: … 1-methyl-1,2-dihydroquinolin-2-one …

1,2-dichlorobenzene

1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound by the presence of two adjacent chlorine atoms. 1,2-dichlorobenzene is used as a precursor for agrochemicals, as a solvent for...
Experimental
Matched Synonyms: … 2-Dichlorobenzene …

Aspergillopepsin-2

Experimental
Matched Name: … Aspergillopepsin-2 …

CERE-120

CERE-120 is an investigational drug consisting of an adeno-associated virus (AAV) that was engineered to carry the human gene for neurturin, a neurotrophic (growth) factor. It was under investigation in clinical trials for the treatment of Parkinson's Disease.
Investigational
Matched Synonyms: … adeno-associated virus serotype 2 [AAV2]-neurturin [NTN] …
Displaying drugs 8376 - 8400 of 11301 in total