Displaying drugs 8401 - 8425 of 11462 in total
2,2-Dimethylbutyrate
Investigational
Meglutol
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Experimental
Matched Synonyms: … 3-hydroxy-3-methylglutaric acid …
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid …
Matched Iupac: … 3-hydroxy-3-methylpentanedioic acid …
(R)-methylmalonyl-CoA
Experimental
Matched Synonyms: … (R)-2-Methyl-3-oxopropanoyl-CoA ... (R)-2-Methyl-3-oxopropionyl-CoA ... (R)-3-Oxo-2-methylpropanoyl-CoA …
Matched Iupac: … (2R)-3-({2-[(3-{[(2R)-4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan ... methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-1,2-dihydroxy-3,3-dimethylbutylidene]amino}-1- ... hydroxypropylidene)amino]ethyl}sulfanyl)-2-methyl-3-oxopropanoic acid …
Matched Iupac: … (2R)-3-({2-[(3-{[(2R)-4-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan ... methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)-1,2-dihydroxy-3,3-dimethylbutylidene]amino}-1- ... hydroxypropylidene)amino]ethyl}sulfanyl)-2-methyl-3-oxopropanoic acid …
S-(2,4-dinitrophenyl)glutathione
Experimental
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-[(2,4-dinitrophenyl)sulfanyl]ethyl]carbamoyl}butanoic …
3-Iodo-Tyrosine
Experimental
Matched Name: … 3-Iodo-Tyrosine …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3-iodophenyl)propanoic acid …
AEG35156
A second-generation synthetic antisense oligonucleotide with potential antineoplastic activity. AEG35156 selectively blocks the cellular expression of X-linked inhibitor of apoptosis protein (XIAP), a pivotal inhibitor of apoptosis that is overexpressed in many tumors. This agent reduces total levels of XIAP in tumor cells, working synergistically with cytotoxic drugs to overcome...
Investigational
GED-0507-34-Levo
GED-0507-34-Levo is under investigation in clinical trial NCT02808390 (Efficacy and Safety Study of Ged-0507-34-levo for Treatment of UC).
Investigational
Matched Iupac: … (2S)-3-(4-aminophenyl)-2-methoxypropanoic acid …
Tonabersat
Investigational
Matched Iupac: … N-[(3S,4S)-6-acetyl-3-hydroxy-2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ioforminol
Ioforminol has been used in trials studying the diagnostic of Cardio Renal Safety in High-risk Elderly Subjects Undergoing a Coronary CATH With or Without PCI.
Investigational
Matched Iupac: … }-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide ... 5-{N-[3-(N-{3,5-bis[(2,3-dihydroxypropyl)carbamoyl]-2,4,6-triiodophenyl}formamido)-2-hydroxypropyl]formamido …
D-Cysteine
A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
Experimental
Matched Synonyms: … D-Amino-3-mercaptopropionic acid ... (2S)-2-amino-3-mercaptopropanoic acid ... (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
Matched Iupac: … (2S)-2-amino-3-sulfanylpropanoic acid …
5-fluorouridine
5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine base attached to a sugar. 5-fluorouridine is known to target uridine phosphorylase. FUrd is often used in chemical and biochemical...
Experimental
Matched Iupac: … 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-fluoro-1,2,3,4-tetrahydropyrimidine-2,4 …
Matched Description: … 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … 5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fitusiran
Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational
Riferminogene pecaplasmid
Riferminogene pecaplasmid (non-viral fibroblast growth factor 1; NV1FGF) is a recombinant DNA plasmid in a pCOR backbone allowing expression of human FGF1.
Investigational
Matched Synonyms: … Non-viral fibroblast growth factor 1 …
Matched Description: … Riferminogene pecaplasmid (non-viral fibroblast growth factor 1; NV1FGF) is a recombinant DNA plasmid …
Matched Description: … Riferminogene pecaplasmid (non-viral fibroblast growth factor 1; NV1FGF) is a recombinant DNA plasmid …
GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
Experimental
Matched Name: … GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
Matched Iupac: … 3,4-d][1,3]dioxol-2-yl]phosphonic acid ... [(2S,3aR,4R,6R,6aR)-4-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-6-(hydroxymethyl)-tetrahydro-2H-furo[ …
Ronopterin
Ronopterin has been used in trials studying the treatment of Traumatic Brain Injury.
Investigational
Matched Iupac: … (1R,2S)-1-[(6R)-2,4-diamino-5,6,7,8-tetrahydropteridin-6-yl]propane-1,2-diol …
2-Ammoniobut-3-Enoate, 2-Amino-3-Butenoate
Experimental
Matched Name: … 2-Ammoniobut-3-Enoate, 2-Amino-3-Butenoate …
Matched Iupac: … (2R)-2-azaniumylbut-3-enoate …
Matched Iupac: … (2R)-2-azaniumylbut-3-enoate …
Azimilide
Azimilide is an investigational class III anti-arrhythmic drug that blocks fast and slow components of the delayed rectifier cardiac potassium channels. It is not approved for use in any country, but is currently in clinical trials in the United States.
Investigational
Matched Iupac: … 1-({[5-(4-chlorophenyl)furan-2-yl]methylidene}amino)-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CHROMOPHORE (ASP-TYR-GLY)
Experimental
Matched Iupac: … (3S)-3-amino-3-[(4Z)-1-(carboxymethyl)-4-[(4-hydroxyphenyl)methylidene]-5-oxo-4,5-dihydro-1H-imidazol …
NCX 701
Nitroparacetamol (NCX-701) is a newly synthesized nitric oxide-releasing derivative of paracetamol.
Investigational
Matched Iupac: … 4-acetamidophenyl 4-(nitrooxy)butanoate …
Meclinertant
Investigational
Matched Iupac: … 2-[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-amido]adamantane-2-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
2-HYDROXY-5-{[(1E)-2-PHENYLETHYLIDENE]AMINO}-L-TYROSINE
Experimental
Matched Iupac: … (2S)-2-amino-3-{2,4-dihydroxy-5-[(E)-(2-phenylethylidene)amino]phenyl}propanoic acid …
(1R,2S)-2-Phenylcyclopropanaminium
A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)
Experimental
Matched Synonyms: … (1R,2S)-tranylcypromine(1+) …
Matched Iupac: … (1R,2S)-2-phenylcyclopropan-1-aminium …
Matched Iupac: … (1R,2S)-2-phenylcyclopropan-1-aminium …
Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate
Experimental
Matched Name: … Tert-Butyl(1s)-1-Cyclohexyl-2-Oxoethylcarbamate …
Matched Iupac: … tert-butyl N-[(1S)-1-cyclohexyl-2-oxoethyl]carbamate …
Matched Iupac: … tert-butyl N-[(1S)-1-cyclohexyl-2-oxoethyl]carbamate …
Beta-D-Glucopyranose Spirohydantoin
Experimental
Matched Iupac: … (5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione …
Piperine
Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Investigational
Matched Iupac: … (2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 8401 - 8425 of 11462 in total