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Displaying drugs 826 - 850 of 1266 in total
Zalifrelimab is under investigation in clinical trial NCT03894215 (Phase 2 Study of Anti-pd-1 Independently or in Combination With Anti-ctla-4 in Second-line Cervical Cancer).
Investigational
Matched Synonyms: … A human monoclonal antibody targeting cytotoxic T lymphocyte associated protein 4 (ctla4) …
An opioid analgesic chemically related to and with an action resembling that of meperidine, but more rapid in onset and of shorter duration. It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental procedures. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1067)
Experimental
Illicit
Matched Synonyms: … beta-Prodine …
Matched Description: … rapid in onset and of shorter duration. ... An opioid analgesic chemically related to and with an action resembling that of meperidine, but more ... It has been used in obstetrics, as pre-operative medication, for minor surgical procedures, and for dental …
Experimental
Matched Synonyms: … alpha-beta methylene ADP-ribose …
Experimental
Matched Synonyms: … beta-mercaptoethanol …
Investigational
Matched Synonyms: … BETA-1B-GLYCOPROTEIN …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Beta-Globulins …
Experimental
Matched Synonyms: … 4-methylumbelliferyl beta-D-glucoside ... 4-Methylumbelliferyl-beta-glucoside ... 4-Methylumbelliferyl-beta-D-glucoside …
Matched Name: … 4-methylumbelliferyl beta-D-glucoside …
Experimental
Matched Name: … beta-D-galactopyranosyl-(1->4)-beta-D-galactopyranose …
Investigational
Matched Synonyms: … tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody ... monoclonal Amab788 γ1-chain), disulfide with human-Mus musculus monoclonal Amab788 κ-chain, dimer, 121,121′-dioxime
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … 2-amino-2-deoxy-beta-D-galactopyranose …
Matched Name: … beta-D-Galactosamine …
Experimental
Matched Name: … Methyl beta-galactoside …
Experimental
Matched Name: … beta-D-fucose …
Investigational
Matched Name: … 7-beta-Hydroxyepiandrosterone …
Investigational
Matched Name: … Sulfobutylether-beta-cyclodextrin …
Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Description: … side effects, notably gastrointestinal hypomotility and orthostatic hypotension. ... [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other ... particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … CLOZAPIN BETA 25MG ... CLOZAPIN BETA 50MG ... CLOZAPIN BETA 100MG …
Experimental
Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
Obexelimab is under investigation in clinical trial NCT02725515 (A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus).
Investigational
Matched Synonyms: … humanized anti-CD19, Fc engineered, monoclonal antibody with enhanced binding to FcyRIIb ... XMAB5871 (HUMANIZED ANTI-CD19 ANTIBODY WITH AN FC PORTION ENGINEERED FOR INCREASED AFFINITY (200- TO …
Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated Plasmodium falciparum infections [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2011 in combination with DB13941 as the product Eurartesim. Artemisinin combination therapy is highly effective against malaria and...
Approved
Experimental
Investigational
Matched Synonyms: … beta-Dihydroartemisinin …
Matched Description: … Artenimol is an artemisinin derivative and antimalarial agent used in the treatment of uncomplicated ... Artemisinin combination therapy is highly effective against malaria and stongly recommended by the World …
Matched Categories: … Artemisinin and derivatives ... artenimol and piperaquine ... Antiparasitic Products, Insecticides and Repellents …
Humanized IgG1 Mab that binds to the human interleukin-2 receptor (anti-Tac or anti-CD25). Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. The human sequences were derived from the constant domains of human IgG1 and the variable framework regions of the Eu myeloma antibody. The murine sequences...
Investigational
Withdrawn
Matched Synonyms: … Daclizumab beta
Matched Description: … who are not hight immunized, for commercial reasons and confirmed that this decision was not related ... Daclizumab is a composite of human (90%) and murine (10%) antibody sequences. ... of the Eu myeloma antibody. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Interleukin-2 Receptor Blocking Antibody ... Interleukin 2 Receptor-directed Antibody Interactions …
Nicorandil is an orally efficacious vasodilatory drug and antianginal agent marketed in the UK, Australia, most of Europe, India, Philippines, Japan, South Korea, and Taiwan. It is not an approved drug by FDA. It is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium...
Approved
Investigational
Matched International brands: … Av-Cor ... K-Cor
Matched Description: … It is often used for patients with angina who remain symptomatic despite optimal treatment with other ... It is shown to dilate normal and stenotic coronary arteries and reduces both ventricular preload and ... , most of Europe, India, Philippines, Japan, South Korea, and Taiwan. …
Experimental
Matched Synonyms: … 2-deoxy-2-fluoro-beta-D-galactose ... 2-FLUORO-2-DEOXY-BETA-D-GALACTOPYRANOSE …
Willardiine is a compound isolated from seeds of Acacia willariana.
Experimental
Matched Synonyms: … beta-(2,4-Dihydroxypyrimidin-1-yl)alanine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Experimental
Matched Synonyms: … beta-Cryptoxanthin …
Matched Categories: … Diet, Food, and Nutrition …
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-meprodine ... beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others.
Investigational
Matched Synonyms: … Chimeric monoclonal antibody to mesothelin …
Matched Description: … Amatuximab has been used in trials studying the treatment and basic science of Mesothelioma, Ovarian ... Cancer, Ovarian Neoplasms, Pancreatic Cancer, and Mesothelioma, Malignant, among others. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … beta-(4-Chlorophenyl)gaba ... beta-(Aminomethyl)-p-chlorohydrocinnamic acid ... beta-(p-Chlorophenyl)-gamma-aminobutyric acid …
Matched Description: … [A245323, A245338] Baclofen is used to manage severe muscle spasms of cerebral or spinal cord origins ... , including multiple sclerosis and traumatic brain injury. ... [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 826 - 850 of 1266 in total