Displaying drugs 826 - 850 of 1202 in total
SGX-523
A MET receptor tyrosine kinase inhibitor.
Investigational
Matched Synonyms: … 6-{[6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline …
Matched Iupac: … 6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline …
Matched Iupac: … 6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline …
Avasopasem
Investigational
Matched Synonyms: … ,21AS)-1,2,3,4,4A,5,6,12,13,13A,14,15,16,17,17A,18,19,20,21,21A-EICOSAHYDRO-11,7-NITRILO-7H-DIBENZO(B, …
Quetiapine
Initially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects during long-term treatment. It is well-tolerated and a suitable option for some patients with high...
Approved
Matched Synonyms: … 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol …
Matched Description: … as [clozapine] and [olanzapine]. ... in schizophrenia, major depression, and bipolar disorder. ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Bio-quetiapine ... Bio-quetiapine XR ... QUETIAPINA SANDOZ BV …
Matched Description: … as [clozapine] and [olanzapine]. ... in schizophrenia, major depression, and bipolar disorder. ... [L8546] Quetiapine demonstrates a high level of therapeutic efficacy and low risk of adverse effects …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Bio-quetiapine ... Bio-quetiapine XR ... QUETIAPINA SANDOZ BV …
KITE-222
Investigational
Matched Synonyms: … therapy engineered to express an antibody-derived single-chain variable fragment that recognizes C-type …
Budesonide
Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532]
Budesonide was granted FDA approval on 14 February 1994. It is also available in a combination product...
Approved
Matched Description: … of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis. ... Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Corticosteroids, Potent (Group III) ... Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide …
Matched Products: … DANKIAL-B ... B-CORT ® 50 ... B-CORTUNGÛENTO …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Corticosteroids, Potent (Group III) ... Alimentary Tract and Metabolism ... salbutamol and budesonide ... formoterol and budesonide ... salmeterol and budesonide …
Matched Products: … DANKIAL-B ... B-CORT ® 50 ... B-CORTUNGÛENTO …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Products: … Truemed Group LLC …
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen
Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by Neisseria meningitidis serogroup W-135. The vaccine contains N. meningitis serogroup W-135 capsular polysaccharide antigens that are purified and individually conjugated to diphtheria toxoid protein that are...
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an …
Matched Description: … vaccine contains *N. meningitis* serogroup W-135 capsular polysaccharide antigens that are purified and ... active intramuscular immunization for the prophylaxis of invasive meningococcal disease caused by *Neisseria ... Neisseria meningitidis group w-135 capsular polysaccharide diphtheria toxoid conjugate antigen is an …
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Matched Description: … Neisseria meningitidis group a capsular oligosaccharide diphtheria crm197 protein conjugate antigen is …
Thieno[2,3-B]Pyridine-2-Carboxamidine
Experimental
Matched Name: … Thieno[2,3-B]Pyridine-2-Carboxamidine …
Matched Iupac: … [amino({thieno[2,3-b]pyridin-2-yl})methylidene]azanium …
Matched Iupac: … [amino({thieno[2,3-b]pyridin-2-yl})methylidene]azanium …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Synonyms: … (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b) ... 12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b) …
Matched Description: … [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … tamsulosin and tadalafil ... ambrisentan and tadalafil ... macitentan and tadalafil ... finasteride and tadalafil ... Genito Urinary System and Sex Hormones …
Matched Products: … Bio-tadalafil ... TADALAFIL SANDOZ BV …
Matched Description: … [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … tamsulosin and tadalafil ... ambrisentan and tadalafil ... macitentan and tadalafil ... finasteride and tadalafil ... Genito Urinary System and Sex Hormones …
Matched Products: … Bio-tadalafil ... TADALAFIL SANDOZ BV …
Vebicorvir
Investigational
Matched Synonyms: … 5,5,11-trioxo-n-((2-(trifluoromethyl)-1,3-thiazol-5-yl)methyl)-10,11-dihydro-5h- 5.lambda.6-dibenzo(b, ... Dibenzo(b,f)(1,4)thiazepine-8-carboxamide, 10,11-dihydro-11-oxo-n-((2-(trifluoromethyl)-5-thiazolyl)methyl …
Alnuctamab
Investigational
Matched Synonyms: … An asymmetric immunoglobulin G1 (IgG1)-based, B-cell maturation antigen (BCMA) x CD3 T-cell bispecific …
Mannitol
Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … may be reduced. ... or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... (CPD) AND OPTISOL (AS-5) Red Cell Preservative …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Diet, Food, and Nutrition ... Blood Substitutes and Perfusion Solutions …
Matched Products: … B. BRAUN OSMOFUNDIN 20% ... B. BRAUN OSMOFUNDIN 10% (500ML) ... %20 MANNITOL ÇÖZELTISI BFS,150 ML,1 ŞIŞE,SETLI …
Matched Mixtures name: … TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND ... TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative ... (CPD) AND OPTISOL (AS-5) Red Cell Preservative …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Diet, Food, and Nutrition ... Blood Substitutes and Perfusion Solutions …
Matched Products: … B. BRAUN OSMOFUNDIN 20% ... B. BRAUN OSMOFUNDIN 10% (500ML) ... %20 MANNITOL ÇÖZELTISI BFS,150 ML,1 ŞIŞE,SETLI …
Sotatercept
Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN ... ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP ... homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type ... [L50351] On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Typhoid Vi polysaccharide vaccine
Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. The vaccine contains the purified cell surface Vi polysaccharide extracted from...
Approved
Matched Synonyms: … Salmonella typhi TY2 Vi polysaccharide antigen ... Typhoid Vi Polysaccharide Vaccine, S typhi Ty2 strain …
Matched Description: … It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for ... , S typhi Ty2* strain. ... contains the purified cell surface Vi polysaccharide extracted from *Salmonella enterica* serovar *Typhi …
Matched Categories: … Inactivated Salmonella Typhi Vaccine …
Matched Description: … It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for ... , S typhi Ty2* strain. ... contains the purified cell surface Vi polysaccharide extracted from *Salmonella enterica* serovar *Typhi …
Matched Categories: … Inactivated Salmonella Typhi Vaccine …
Rotenone
Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Vet approved
Matched Synonyms: … (12aS,6aS,2R)-8,9-dimethoxy-2-(1-methylvinyl)-1,2-dihydrochromano[3,4-b]furano [2,3-h]chroman-6-one ... [2R-(2α,6aα,12aα)]-1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethenyl)[1]benzopyrano[3,4-b]furo[2,3 …
Matched Description: … It has broad spectrum insecticide and pesticide activity and is also toxic to fish. …
Matched Description: … It has broad spectrum insecticide and pesticide activity and is also toxic to fish. …
Edecesertib
Edecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).
Investigational
Matched Synonyms: … 3-Pyridinecarboxamide, 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2 ... 4-{[(1R)-1-cyanoethyl]amino}-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3- methylbutyl …
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen
Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen is a vaccine.
Approved
Matched Name: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
Matched Description: … Neisseria meningitidis group w-135 capsular oligosaccharide diphtheria crm197 protein conjugate antigen …
(-)-beta-Elemene
Investigational
Matched Synonyms: … (-)-B-elemene ... Cyclohexane, 1-ethenyl-1-methyl-2,4-bis(1-methylethenyl)-, (1s,2s,4r)- …
Matched Iupac: … (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane …
Matched Iupac: … (1S,2S,4R)-1-ethenyl-1-methyl-2,4-bis(prop-1-en-2-yl)cyclohexane …
AB-22
Investigational
Matched Synonyms: … Hydrazinecarboxamide, n-(2-chloro-6-propoxy-4-pyridinyl)-2-(1,3-dimethyl-4-(1-methylethyl)-1h-pyrazolo(3,4-b) ... N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1h-pyrazolo(3,4-b)pyridin ... N-(2-chloro-6-propoxypyridin-4-yl)-2-(2-hydroxyethyl)-2-(4-isopropyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin …
Matched Iupac: … 1-(2-chloro-6-propoxypyridin-4-yl)-3-{[1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl](2 …
Matched Iupac: … 1-(2-chloro-6-propoxypyridin-4-yl)-3-{[1,3-dimethyl-4-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-6-yl](2 …
Amlexanox
Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and rhinitis. Amlexanox as a topical paste is a well tolerated treatment of recurrent aphthous ulcers. Recurrent aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and 50% of...
Approved
Investigational
Withdrawn
Matched Synonyms: … 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid …
Matched Description: … Amlexanox is an antiallergic drug, clinically effective for atopic diseases, especially allergic asthma and ... aphthous ulcer (RAU) is the most prevalent oral mucosal disease in humans, estimated to affect between 5% and …
Matched Categories: … Alimentary Tract and Metabolism …
Hydroxypropyl betadex
Hydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
Investigational
Matched Synonyms: … 2-Hydroxypropyl-b-cyclodextrin …
Matched Description: … NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type …
Matched Description: … NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type …
Interferon gamma-1b
Human Interferon gamma-1b (140 residues), produced from E. coli. Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium containing the DNA which encodes for the human protein. Purification of the product is achieved by conventional column chromatography.
The sequence displayed is a cDNA sequence which...
Approved
Investigational
Matched Synonyms: … Interferon gamma 1-b …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Purification of the product is achieved by conventional column chromatography. ... Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Description: … et. al. and not specifically interferon gamma 1b. ... Purification of the product is achieved by conventional column chromatography. ... Production of Actimmune is achieved by fermentation of a genetically engineered Escherichia coli bacterium …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Synonyms: … 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal ... reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Iupac: … 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one …
Matched Description: … Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal ... reports of severe adverse effects including ischemic colitis, severely obstructed or ruptured bowel, and ... Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer due to numerous …
Matched Categories: … Alimentary Tract and Metabolism …
Displaying drugs 826 - 850 of 1202 in total