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Displaying drugs 826 - 850 of 1198 in total
Cobicistat, marketed under the name Tybost (formerly GS-9350), indicated for treating infection with human immunodeficiency virus (HIV). Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered agents that are metabolized...
Approved
Matched Synonyms: … thiazol-4-yl)methyl](methyl)carbamoyl}amino)-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate
Matched Iupac: … -yl)-1,3-thiazol-4-yl]methyl})carbamoyl]amino}-4-(morpholin-4-yl)butanamido]-1,6-diphenylhexan-2-yl]carbamate
Matched Description: … activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and ... exposure of anti-retrovirals (ARVs) without increasing dosage allows for better treatment outcomes and
Matched Categories: … darunavir and cobicistat ... atazanavir and cobicistat ... Metabolic Side Effects of Drugs and Substances ... emtricitabine, tenofovir alafenamide, darunavir and cobicistat ... emtricitabine, tenofovir disoproxil, elvitegravir and cobicistat …
Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine. It is primarily found endogenously in the skeletal muscles of vertebrates where it serves a critical role as a rapidly acting energy buffer for muscle cell actions like contractions via its ability to regenerate adenosine triphosphate (ATP) from...
Nutraceutical
Matched Synonyms: … Creatine phosphate ... Creatine phosphic acid …
Matched Description: … Phosphocreatine - or creatine phosphate - is the phosphorylated form of creatine. …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly...
Approved
Vet approved
Matched Description: … Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged ... Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate …
Matched Salts name: … Piperazine hexahydrate ... Piperazine phosphate
Matched Categories: … Piperazine and Derivatives ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … EPULSARINA® PIPERAZINA HEXAHIDRATO
Experimental
Matched Name: … Zinc Substituted Heme C …
Matched Iupac: … lambda4-zinc(4+) (20E)-10,14-bis(2-carboxyethyl)-5,20-diethylidene-4,9,15,19-tetramethyl-21,22,23,24- …
Matched Categories: … Zinc Compounds …
Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Synonyms: … Betamethasone 21-phosphate ... Betamethasone dihydrogen phosphate ... Betamethasone 21-(dihydrogen phosphate) …
Matched Name: … Betamethasone phosphate
Matched Description: … L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium and ... [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994] ... Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible [betamethasone …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Name: … Calcium lactate gluconate …
Matched Mixtures name: … CALCIUM SANDOZ ... CALCIUM SANDOZ FORTE ... CALCIUM SANDOZ FORTE …
Matched Categories: … Alimentary Tract and Metabolism ... Calcium Salts ... calcium lactate gluconate …
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Matched Synonyms: … 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
Matched Description: … [A255647] Diazoxide also exhibits hypotensive activity and reduces arteriolar smooth muscle and vascular ... and electrolyte disturbances. ... Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels …
Matched Categories: … Potassium Channel Opener …
Approved
Experimental
Matched Name: … Zirconium chloride hydroxide …
Amprolium is a coccidiostat used in poultry.
Experimental
Vet approved
Matched Synonyms: … 1-((4-amino-2-Propyl-5-pyrimidinyl)methyl)-2-picolinium chloride
Matched Iupac: … 1-[(4-amino-2-propylpyrimidin-5-yl)methyl]-2-methylpyridin-1-ium chloride
Experimental
Matched Name: … Potassium hydrogen DL-aspartate …
Matched Iupac: … potassium 3-amino-3-carboxypropanoate …
Experimental
Matched Synonyms: … Iodopropynyl butyl carbamate
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)
Approved
Matched Synonyms: … 6-trifluoromethyl-3-benzyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide ... ±-3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Matched Description: … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. ... It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders …
Matched Mixtures name: … Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide ... Nadolol and Bendroflumethiazide …
Matched Categories: … bendroflumethiazide and potassium ... Low-Ceiling Diuretics and Potassium-Sparing Agents ... bendroflumethiazide and potassium-sparing agents ... Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones …
Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration.
Experimental
Matched Synonyms: … 1,1,1-Trifluoro-3-(2-thenoyl)acetone
Matched Description: … Thenoyltrifluoroacetone is a chelating agent and inhibitor of cellular respiration. …
Approved
Matched Synonyms: … Iron(II) glycine sulfate …
Matched Iupac: … lambda2-iron(2+) sulfuric acid bis(2-aminoacetate) …
Matched Categories: … Blood and Blood Forming Organs ... Iron Preparations ... Iron Bivalent, Oral Preparations …
Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Synonyms: … Sodium acid phosphate ... Sodium primary phosphate ... Sodium dihydrogen phosphate
Matched Name: … Sodium phosphate, monobasic …
Matched Iupac: … sodium dihydrogen phosphate
Matched Description: … Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate ... Dibasic Sodium Phosphate, Monobasic Potassium Phosphate and Monobasic Sodium Phosphate
Matched Salts name: … Sodium phosphate, monobasic, dihydrate ... Sodium phosphate, monobasic, monohydrate …
Matched Categories: … Potassium Salt ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Phosphate salts …
Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably. An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes, loss of control over urination. Trospium is manufactured by Indevus Pharmaceutical Inc. and...
Approved
Matched Description: … [L6208] An overactive bladder leads to an increased urge to urinate, frequent urination, and sometimes ... [L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007 …
Matched Salts name: … Trospium chloride
Matched Categories: … Alimentary Tract and Metabolism ... trospium and analgesics ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … Trospium Chloride ... Trospium Chloride ER …
Experimental
Matched Synonyms: … Sorbitol 6-phosphate ... D-Sorbitol 6-phosphate ... Sorbitol-6-phosphate
Matched Name: … D-glucitol 6-phosphate
Experimental
Matched Synonyms: … Diethyl phosphite ... Diethyl acid phosphite ... Diethyl hydrogen phosphite
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and ... This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … IROTEN 40 MG/2 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 100 MG/5 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IROTEN 500 MG/25 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET …
Casein allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Calcium caseinate …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Fluids and Secretions ... Diet, Food, and Nutrition …
Experimental
Matched Synonyms: … Adenosine 3'-phosphate-5'-phosphate ... Phosphoadenosine phosphate ... 3'-Phosphoadenosine 5'-phosphate
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Description: … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and ... [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. …
Matched Mixtures name: … Co-Acetan - Tabletten ... Co-Acetan mite - Tabletten ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Matched Products: … Acetan 5 mg - Tabletten ... Acetan 10 mg - Tabletten ... Acetan 20 mg - Tabletten …
Experimental
Matched Synonyms: … Phosphate-32 ... Phosphate-32P …
Matched Name: … Phosphate ion P-32 …
Matched Iupac: … (32P)phosphate
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Topical Products for Joint and Muscular Pain …
Approved
Matched Synonyms: … Sodium phosphate 32P ... Sodium phosphate (32P) ... Sodium phosphate P 32 …
Matched Name: … Sodium phosphate P 32 …
Matched Iupac: … disodium hydrogen (32P)phosphate
Matched Categories: … sodium phosphate (32P) …
Displaying drugs 826 - 850 of 1198 in total