Displaying drugs 8501 - 8525 of 11209 in total
GSK2798745
GSK2798745 is under investigation in clinical trial NCT03372603 (A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough).
Investigational
Matched Iupac: … 1-{[(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
GSK2245035
GSK2245035 is under investigation in clinical trial NCT02833974 (Effect of the GSK2245035 on the Allergen-induced Asthmatic Response).
Investigational
Matched Iupac: … 6-amino-2-[(2S)-pentan-2-yloxy]-9-[5-(piperidin-1-yl)pentyl]-8,9-dihydro-7H-purin-8-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
S-(2-oxo)pentadecylcoa
Experimental
Matched Name: … S-(2-oxo)pentadecylcoa …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3S)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(2-oxopentadecyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl ... ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3S)-3-hydroxy-2,2-dimethyl ... -3-{[2-({2-[(2-oxopentadecyl)sulfanyl]ethyl}carbamoyl)ethyl]carbamoyl}propoxy]phosphoryl}oxy)phosphoryl ... ]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid …
Glial growth factor 2
Glial growth factor 2 has been used in trials studying the treatment of Heart Failure.
Investigational
Matched Name: … Glial growth factor 2 …
Matched Description: … Glial growth factor 2 has been used in trials studying the treatment of Heart Failure. …
Matched Description: … Glial growth factor 2 has been used in trials studying the treatment of Heart Failure. …
2-phospho-D-glyceric acid
A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration.
Experimental
Matched Synonyms: … 2-phospho-D-glycerate ... D-glycerate 2-phosphate …
Matched Name: … 2-phospho-D-glyceric acid …
Matched Iupac: … (2R)-3-hydroxy-2-(phosphonooxy)propanoic acid …
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …
Matched Name: … 2-phospho-D-glyceric acid …
Matched Iupac: … (2R)-3-hydroxy-2-(phosphonooxy)propanoic acid …
Matched Description: … A 2-phosphoglyceric acid in which the glyceric acid moiety has D (R) configuration. …
Telotristat
A tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-{2-amino-6-[(1R)-1-[4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy ... ]pyrimidin-4-yl}phenyl)propanoic acid …
3,5-Diaminophthalhydrazide
Experimental
D-Myo-Inositol-1,4-Bisphosphate
Experimental
Matched Iupac: … {[(1R,2R,3R,4R,5R,6S)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphonic acid …
GS 0573
Investigational
Matched Synonyms: … 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine …
Matched Iupac: … {[2-(2,6-diamino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … {[2-(2,6-diamino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Delta-2-Albomycin A1
Experimental
Matched Name: … Delta-2-Albomycin A1 …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl …
Matched Iupac: … (8S,11R,14R)-14-amino-8-{[(1S)-1-{[(1R,2R)-2-[(2R,3S,4S,5R)-5-[(4Z)-4-(carbamoylimino)-3-methyl-2-oxo ... -1,2,3,4-tetrahydropyrimidin-1-yl]-3,4-dihydroxythiolan-2-yl]-1-carboxy-2-hydroxyethyl]carbamoyl}-2-hydroxyethyl …
Nafithromycin
Nafithromycin is under investigation in clinical trial NCT02903836 (Phase II Study of Oral Nafithromycin in CABP).
Investigational
Matched Iupac: … (Z,3R,3aS,4R,6R,8R,9R,10R,12R,15R,15aS)-9-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2- ... -1,3,4-thiadiazol-2-yl]ethoxy]-tetradecahydro-2H-furo[2,3-c]oxacyclotetradecane-3-carboximidamide ... yl]oxy}-15-ethyl-8-methoxy-4,6,8,10,12,15a-hexamethyl-2,5,11,13-tetraoxo-N'-[(1S)-1-[5-(pyridin-2-yl) …
Reldesemtiv
Reldesemtiv is under investigation in clinical trial NCT03160898 (A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)).
Investigational
Matched Iupac: … 1-[2-({[(1r,3r)-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl]methyl}amino)pyrimidin-5-yl]-1H-pyrrole-3 …
N-acetyl-D-glucosamine-6-phosphate
Experimental
Matched Synonyms: … 2-acetamido-2-deoxy-6-O-phosphono-D-glucopyranose …
Matched Iupac: … {[(2R,3S,4R,5R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid …
Matched Iupac: … {[(2R,3S,4R,5R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid …
Brodimoprim-4,6-Dicarboxylate
Brodimoprim-4,6-dicarboxylate is a solid. This compound belongs to the anisoles. These are organic compounds contaiing a methoxybenzene or a derivative thereof. This medication is known to target the protein dihydrofolate reductase.
Experimental
Matched Iupac: … 2,4-diamino-5-[(4-bromo-3-{[(4S)-4,6-dicarboxylatohexyl]oxy}-5-methoxyphenyl)methyl]pyrimidin-1-ium …
Camptothecin
Camptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
Experimental
(S)-atrolactic acid
Experimental
Matched Synonyms: … (S)-2-Hydroxy-2-phenylpropanoic acid ... (S)-2-Phenyllactic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylpropanoic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylpropanoic acid …
Pateclizumab
Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis).
Investigational
Agatolimod
Agatolimod is under investigation in clinical trial NCT00471471 (Vaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery).
Investigational
Taniraleucel
Investigational
Matched Synonyms: … differentiated in the presence of cytokines including thrombopoietin, SCF, Flt3 ligand, IL-7, IL-15 and IL-2 …
(Rp)-cAMPS
Experimental
Matched Synonyms: … (Rp)-adenosine-3',5'-cyclic monophosphorothioate ... adenosine-3',5'-cyclic monophosphorothioate, Rp-isomer …
Matched Iupac: … ]dioxaphosphinin-2-one ... (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … ]dioxaphosphinin-2-one ... (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Fluciclovine
Fluciclovine is under investigation in clinical trial NCT03036943 (Fluciclovine (18F) Imaging of Breast Cancer).
Investigational
Matched Synonyms: … Anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid ... Cyclobutanecarboxylic acid, 1-amino-3-fluoro-, trans- …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
Matched Iupac: … (1r,3r)-1-amino-3-fluorocyclobutane-1-carboxylic acid …
3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide
Experimental
Matched Synonyms: … 3-(α-D-Galactopyranosyloxy)-5-nitrobenzamide ... 5-aminocarbonyl-3-nitrophenyl-alpha-D-galactopyranose …
Matched Name: … 3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide …
Matched Iupac: … 3-nitro-5-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzamide …
Matched Name: … 3-(alpha-D-Galactopyranosyloxy)-5-nitrobenzamide …
Matched Iupac: … 3-nitro-5-{[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}benzamide …
anti-OX40 antibody BMS 986178
A macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Investigational
N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE
Experimental
Matched Name: … N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE …
Matched Iupac: … methyl[(2R)-1-phenylpropan-2-yl](prop-2-en-1-yl)amine …
Matched Iupac: … methyl[(2R)-1-phenylpropan-2-yl](prop-2-en-1-yl)amine …
2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
Experimental
Matched Name: … 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
Matched Iupac: … 2-hydroxy-5-[(2-sulfanylethyl)sulfamoyl]benzoic acid …
Displaying drugs 8501 - 8525 of 11209 in total