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Displaying drugs 8551 - 8575 of 10065 in total
Galidesivir is an adenosine analogue that has been investigated for use against Zaire Ebolavirus. In animal studies, galidesivir was effective in increasing the survival rates from infections caused by various pathogens, including Ebola, Marburg, Yellow Fever and Zika viruses. In vitro, it displayed broad-spectrum antiviral activity against various negative- and...
Investigational
Matched Iupac: … (2S,3S,4R,5R)-2-{4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl}-5-(hydroxymethyl)pyrrolidine-3,4-diol …
Matched Description: … [L12039,L12084] Phase 1 clinical trials have begun to determine the safety of this drug in humans. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
ZD6126 has been used in trials studying the treatment of Kidney Neoplasms, Colorectal Neoplasms, Metastases, Neoplasm, and Carcinoma, Renal Cell.
Investigational
Matched Iupac: … {[(8S)-8-acetamido-13,14,15-trimethoxytricyclo[9.4.0.0^{2,7}]pentadeca-1(15),2(7),3,5,11,13-hexaen-5- …
Voxtalisib has been used in trials studying the treatment of Cancer, Melanoma, Lymphoma, Glioblastoma, and Breast Cancer, among others.
Investigational
Matched Iupac: … 2-amino-8-ethyl-4-methyl-6-(1H-pyrazol-5-yl)-7H,8H-pyrido[2,3-d]pyrimidin-7-one …
Matched Categories: … Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Experimental
Matched Iupac: … 4-{[7-bromo-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]oxy}-4-oxobutanoic acid …
Nedisertib is under investigation in clinical trial NCT03770689 (Study of M3814 in Combination With Capecitabine and Radiotherapy in Rectal Cancer).
Investigational
Matched Iupac: … (S)-{2-chloro-4-fluoro-5-[7-(morpholin-4-yl)quinazolin-4-yl]phenyl}(6-methoxypyridazin-3-yl)methanol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Iupac: … 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic …
BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants).
Investigational
Matched Iupac: … 4-(4-{[(6-methoxy-2-{2-methoxyimidazo[2,1-b][1,3,4]thiadiazol-6-yl}-1-benzofuran-4-yl)oxy]methyl}-1,3
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Fosravuconazole is under investigation in clinical trial NCT03378661 (BENDITA BEnznidazole New Doses Improved Treatment and Associations).
Investigational
Matched Iupac: … ({[(2R,3R)-3-[4-(4-cyanophenyl)-1,3-thiazol-2-yl]-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan …
Investigational
Matched Iupac: … }-1,3-thiazolidine-2,4-dione ... 3-{[(3Z)-3-({4-[(morpholin-4-yl)methyl]-1H-pyrrol-2-yl}methylidene)-2-oxo-2,3-dihydro-1H-indol-5-yl]methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … (2S)-4-(2,5-DIFLUOROPHENYL)-N-METHYL-2-PHENYL-N-PIPERIDIN-4-YL-2,5-DIHYDRO-1H-PYRROLE-1-CARBOXAMIDE …
Matched Iupac: … (2S)-4-(2,5-difluorophenyl)-N-methyl-2-phenyl-N-(piperidin-4-yl)-2,5-dihydro-1H-pyrrole-1-carboxamide …
Experimental
Matched Name: … Nz-(1-Carboxyethyl)-Lysine …
Matched Iupac: … (2S)-2-amino-6-{[(1R)-1-carboxyethyl]amino}hexanoic acid …
Experimental
Matched Name: … 4-Hydroxybutan-1-Aminium …
Matched Iupac: … 4-hydroxybutan-1-aminium …
Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally related to IFN-alpha and -beta. It occurs naturally in the human body and is currently being manufactured by Intarcia through genetic engineering. There are multiple routes for administration of omega interferon: injection, an implantable subcutaneous...
Investigational
Matched Synonyms: … Interferon omega-1 ... Human interferon omega 1
Matched Name: … Human interferon omega-1
Matched Description: … Human interferon omega 1 (IFN-omega 1 = IFN-alpha II1) is a recently discovered protein structurally ... The biological activities of IFN-omega 1 and its physiological role are not known to date. …
Florilglutamic acid F-18 is under investigation in clinical trial NCT02370563 (PET Imaging of Intracranial Cancers With 18F-FSPG).
Investigational
Matched Iupac: … (2S,4S)-2-amino-4-[3-(¹⁸F)fluoropropyl]pentanedioic acid …
Experimental
Illicit
PEGylation is a technology for the chemical attachment of polyethylene glycol (PEG) polymer chains to a broad range of drug substances such as peptides and proteins including antibody fragments; small molecules, and other drugs. [Infergen] is a bio-engineered type I interferon alpha that is FDA-approved for the treatment of patients...
Investigational
Matched Synonyms: … PEG INF alfacon-1 ... PEG-interferon alfacon-1 ... Pegylated interferon alfacon-1
Matched Name: … Peginterferon alfacon-1
Experimental
Matched Name: … N-Hydroxy-4-[(4-Methoxylphenyl)Sulfonyl]-2,2-Dimethyl-Hexahydro-1,4-Thiazepine-3(S)-Carboxamide …
Matched Iupac: … (3R)-N-hydroxy-4-(4-methoxybenzenesulfonyl)-2,2-dimethyl-1,4-thiazepane-3-carboxamide …
Experimental
Labetuzumab is a humanized monoclonal antibody to carcinoembryonic antigen that inhibits tumor growth. It is used in radioimmunotherapy.
Investigational
alpha-Hydroxylinoleic acid is under investigation in clinical trial NCT04431258 (ABTL0812 in Combination With FOLFIRINOX for First-line Treatment of Metastatic Pancreatic Study).
Investigational
Vinylglycine is an irreversible inhibitor of aspartate aminotransferase.
Experimental
Matched Synonyms: … (2S)-2-amino-3-butenoic acid …
Matched Iupac: … (2S)-2-aminobut-3-enoic acid …
Experimental
Matched Synonyms: … (Rp)-adenosine-3',5'-cyclic monophosphorothioate ... adenosine-3',5'-cyclic monophosphorothioate, Rp-isomer …
Matched Iupac: … (2R,4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-7-hydroxy-2-sulfanyl-hexahydro-2lambda5-furo[3,2-d][1,3,2 …
Investigational
Matched Synonyms: … 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethylacetamide ... Acetamide, 2-((2-(3-butoxyphenyl)ethyl)amino)-n,n-dimethyl- …
Displaying drugs 8551 - 8575 of 10065 in total