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Displaying drugs 8651 - 8675 of 10982 in total
Experimental
Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV-2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated to the hepatitis B surface antigen . Virus-like particles (VLPs) are protein-based vaccines that stimulate high immune responses because of the VLPs’...
Investigational
Matched Synonyms: … RBD SARS-CoV-2 HBsAg VLP vaccine …
Matched Name: … Receptor binding domain (RBD) SARS-CoV-2 (COVID-19) hepatitis B surface antigen (HBsAg) virus-like particle …
Matched Description: … Receptor binding domain SARS-CoV-2 Hepatitis B surface antigen virus-like particle vaccine (RBD SARS-CoV ... -2 HBsAg VLP vaccine), is a virus-like particle vaccine candidate where the RBD antigen is conjugated …
Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]
Investigational
S-Ethylisothiourea is a nitric oxide synthase inhibitor.
Experimental
Matched Synonyms: … 2-Ethyl-2-thiopseudourea …
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Experimental
Matched Synonyms: … D-2-Hydroxypropanoic acid ... D-2-Hydroxypropionic acid …
Matched Iupac: … (2R)-2-hydroxypropanoic acid …
BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. Investigation shows this vaccine induces neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2 challenge in rhesus macaques . As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials.
Investigational
Matched Synonyms: … Purified inactivated SARS-CoV-2 Vaccine …
Matched Description: … BBIBP-CorV vaccine contains a SARS-CoV-2 strain inactivated inside Vero Cells. ... neutralizing antibodies in several mammalian species while also showing protective efficacy with SARS-CoV-2
Investigational
Matched Synonyms: … 4-(2-Hydroxyethyl)-1-piperazineethane sulfonic acid ... 4-(2-Hydroxyethyl)-1-piperazineethane sulphonic acid …
Matched Iupac: … 2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid …
(Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide is a solid. This compound belongs to the phenylpiperazines. These are compounds containing a phenylpiperazine skeleton, which consists of a piperazine bound to a phenyl group. This drug targets the protein S100B.
Experimental
Matched Name: … (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide …
Matched Iupac: … (Z)-({[2-(4-methylpiperazin-1-yl)phenyl]methyl}imino)thiourea …
Matched Description: … (Z)-2-[2-(4-methylpiperazin-1-yl)benzyl]diazenecarbothioamide is a solid. …
Experimental
Matched Name: … 7-methyl-7,8-dihydroguanosine-5'-diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan ... -2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid …
Experimental
Matched Name: … 4-Methyl-5-Hydroxyethylthiazole Phosphate …
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
Solanezumab is under investigation for the treatment of Dementia, Alzheimers Disease, and Alzheimers Disease, Familial.
Investigational
Experimental
Matched Synonyms: … 2-Butenal ... trans-2-butenal ... trans-but-2-enal …
Matched Iupac: … (2E)-but-2-enal …
Investigational
Ethylmercurithiosalicylic acid is a topical antiseptic used on skin and mucous membranes. It is also used as a preservative in pharmaceuticals.
Experimental
Matched Synonyms: … 2-(ethylmercuri-thio)-benzoic acid ... 2-(ethylmercuriothio)benzoic acid …
Matched Iupac: … [(2-carboxyphenyl)sulfanyl](ethyl)mercury …
RBIO-101 is a recombinant adeno-associated virus vector encoding human CYP4V2 protein.
Investigational
Experimental
Matched Name: … N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE …
Matched Iupac: … 4-{[(1S)-1-[hydroxy({[(2-phenylethyl)carbamoyl]methoxy})phosphoryl]-2-phenylethyl]carbamoyl}butanoic …
Experimental
Matched Name: … 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL …
Matched Iupac: … 6-benzyl-1-[(benzyloxy)methyl]-5-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Experimental
Metrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Vet approved
Investigational
Matched Iupac: … (2S)-2,6-bis[(2S)-5-carbamimidamido-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2,6-diaminohexanamido ... ]acetamido}-3-methylbutanamido]-3-hydroxypropanamido]-4-methylpentanamido]-3-hydroxypropanamido]-3-(4 …
Experimental
Matched Name: … 2-Amino-Vinyl-Phosphate …
Matched Iupac: … {[(1E)-2-aminoethenyl]oxy}phosphonic acid …
Experimental
Matched Name: … 6-Chloro-2-fluoropurine …
Matched Iupac: … 6-chloro-2-fluoro-9H-purine …
Investigational
Matched Synonyms: … 9-(2-(phosphonomethoxy)ethyl)adenine ... 9-(2-phosphonylmethoxyethyl)adenine …
Matched Iupac: … {[2-(6-amino-9H-purin-9-yl)ethoxy]methyl}phosphonic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
LMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.
Investigational
Displaying drugs 8651 - 8675 of 10982 in total