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Displaying drugs 8701 - 8725 of 11427 in total
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the...
Investigational
Matched Iupac: … )-16-(hydroxymethyl)-22-methyl-10-(2-methylpropyl)-37-[2-(methylsulfanyl)ethyl]-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51 ... [(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-[(2S,3R)-2-amino-3-hydroxybutanamido ... ]-49-benzyl-28-[(2S)-butan-2-yl]-31,40-bis(3-carbamimidamidopropyl)-19-(2-carbamoylethyl)-34-(carboxymethyl ... carbamoylpropanamido]-3-hydroxypropanamido]-3-phenylpropanamido]-5-carbamimidamidopentanamido]-3-(4-hydroxyphenyl ... ]propanoyl]pyrrolidin-2-yl]formamido}-5-carbamimidamidopentanamido]-3-hydroxypropanamido]-4-methylpentanamido …
Matched Description: … Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated …
Experimental
Matched Synonyms: … 4-Methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-2H-chromen-2-one …
Investigational
Matched Synonyms: … (2S)-4-(2-METHOXYETHYL-(4-(5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDIN-2-YL)BUTYL)AMINO)-2-(QUINAZOLIN-4-YLAMINO ... (S)-4-[(2-Methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl) ... Butanoic acid, 4-[(2-methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-(4-quinazolinylamino …
Matched Iupac: … (2S)-4-[(2-methoxyethyl)[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butyl]amino]-2-[(quinazolin-4-yl …
Experimental
Matched Synonyms: … Nickel(2+) ... Nickel ion(2+) ... Nickel(2+) ion …
Matched Iupac: … nickel(2+) ion …
Experimental
Matched Synonyms: … (R)-(+)-Tetrahydro-2-furoic acid ... (S)-(-)-2-Tetrahydrofuroic acid ... (2R)-Tetrahydro-2-furancarboxylic acid …
Matched Name: … (S)-2-Tetrahydrofuroic acid …
Matched Iupac: … (2R)-oxolane-2-carboxylic acid …
Gemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
Investigational
Matched Synonyms: … -D-2'DEOXY-2',2'-DIFLUOROCYTIDINE ... 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-octadec-9-enoate ... 5'-O-(trans-9"-octadecenoyl)-1-beta-D-2'deoxy-2',2'-difluorocytidine …
Matched Iupac: … [(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methyl (9E) …
Tempol has been used in trials studying the treatment of Anal Cancer.
Investigational
Experimental
Matched Name: … 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide …
Matched Iupac: … 4-[(4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl)amino]-N-methylbenzene …
Experimental
Matched Name: … 2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid …
Matched Iupac: … 2-(1-carboxy-N-{4-[(2S)-2-acetamido-2-(pentylcarbamoyl)ethyl]naphthalen-1-yl}formamido)benzoic acid …
Experimental
Matched Iupac: … (2S)-2-amino-3-(4-iodophenyl)propanoic acid …
Experimental
Matched Iupac: … (2S)-2-({[(1R)-1-[(2S)-2-{[(benzyloxy)carbonyl]amino}propanamido]ethyl](hydroxy)phosphoryl}oxy)-3-phenylpropanoic …
Taprenepag has been used in trials studying the treatment of Ocular Hypertension and Glaucoma, Open-Angle.
Investigational
Matched Iupac: … 2-{3-[(N-{[4-(1H-pyrazol-1-yl)phenyl]methyl}pyridine-3-sulfonamido)methyl]phenoxy}acetic acid …
Aplidine is a peptide found in tunicates which shows promise in shrinking tumors in pancreatic, stomach, bladder, and prostate cancers. The specific marine organism is Aplidium albicans. Aplidine is also of interest as a potential treatment for some leukemias.
Investigational
Matched Iupac: … (2R)-N-[(3S,6R,7S,10R,11S,15S,17S,20S,25aS)-10-[(2S)-butan-2-yl]-11-hydroxy-3-[(4-methoxyphenyl)methyl ... ]-2,6,17-trimethyl-20-(2-methylpropyl)-1,4,8,13,16,18,21-heptaoxo-15-(propan-2-yl)-docosahydro-1H-pyrrolo ... [2,1-f]1,15-dioxa-4,7,10,20-tetraazacyclotricosan-7-yl]-4-methyl-2-{N-methyl-1-[(2S)-1-(2-oxopropanoyl ... )pyrrolidin-2-yl]formamido}pentanamide …
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Streptolydigin is an antibiotic isolated from culture filtrates of Streptomyces lydicus. It is active against gram-postive bacteria except micrococci.
Experimental
Matched Iupac: … '-oxiran]-3-en-7-yl]-1-hydroxy-4-methylhepta-2,4-dien-1-ylidene]-1-[(2S,5S,6S)-5-hydroxy-6-methyloxan ... -2-yl]-3,5-dioxopyrrolidin-2-yl]-N-methylpropanamide ... (2S)-2-[(2S,4E)-4-[(2E,4E,6R)-6-[(1R,2R,5R,6S,7R)-1,6-dimethyl-8,9-dioxaspiro[bicyclo[3.3.1]nonane-2,2 …
Raclopride has been used in trials studying Parkinson Disease.
Investigational
Matched Iupac: … 3,5-dichloro-N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-hydroxy-6-methoxybenzamide …
Ataciguat has been investigated for the basic science of Aortic Valve Stenosis.
Investigational
Matched Iupac: … 5-chloro-2-(5-chlorothiophene-2-sulfonamido)-N-[4-(morpholine-4-sulfonyl)phenyl]benzamide …
DA-6886 has been used in trials studying the treatment of Irritable Bowel Syndrome.
Investigational
Matched Iupac: … 4-amino-5-chloro-2-methoxy-N-({1-[3-(1H-1,2,3-triazol-1-yl)propyl]piperidin-4-yl}methyl)benzamide …
Experimental
Matched Synonyms: … endo-2-bornanol ... endo-2-camphanol ... endo-2-hydroxycamphane …
Matched Iupac: … 1,7,7-trimethylbicyclo[2.2.1]heptan-2-ol …
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-({[hydroxy({hydroxy[(3R)-3-hydroxy-3-({2-[(2-{[ ... }oxy)phosphoryl]oxy}methyl)oxolan-3-yl]oxy}phosphonic acid ... 2-(4-hydroxyphenyl)-2-oxoethyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)-2,2-dimethylpropoxy]phosphoryl …
Experimental
Matched Iupac: … (2S)-2-[(hydroxycarbamoyl)amino]-3-phenylpropanoic acid …
Experimental
Matched Iupac: … (2R)-2-[N-hydroxy-(C-hydroxycarbonimidoyl)amino]-3-phenylpropanoic acid …
CH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … (2s)-2-((4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)amino)-4-methylene-pentanedioic acid ... 4-methylene-n-(4-(2-(2,4-diaminoquinazolin-6-yl)ethyl)benzoyl)-l-glutamic acid ... L-glutamic acid, n-(4-(2-(2,4-diamino-6-quinazolinyl)ethyl)benzoyl)-4-methylene- …
Experimental
Matched Name: … 1-{2-[(4-CHLOROPHENYL)AMINO]-2-OXOETHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE …
Matched Iupac: … 1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan-2-yl)piperidin-4-yl]-1H-indole-2-carboxamide …
Displaying drugs 8701 - 8725 of 11427 in total