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Displaying drugs 851 - 875 of 1041 in total

Darbepoetin alfa

Human erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … ARANESP 60UG FS MIT ANS ... ARANESP 60 MIKROGRAMM FS ... ARANESP 60UG INJ LSG ANS …

Dabigatran etexilate

Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin inhibitor dabigatran.[A177463, A6970, L34675, L34680] Dabigatran etexilate may be used to decrease the risk of venous thromboembolic events in patients in whom anticoagulation therapy is indicated. In contrast to warfarin, because its anticoagulant effects...
Approved
Matched Description: … Dabigatran etexilate is an oral prodrug that is hydrolyzed to the competitive and reversible direct thrombin …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … PRADAXA 75 MG SERT KAPSUL, 60 ADET ... PRADAXA 110 MG SERT KAPSUL, 60 ADET ... PRADAXA 150 MG SERT KAPSUL, 60 ADET …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Products: … LEDASON 60 MG FİLM KAPLI TABLET, 30 ADET ... LUİGON 60 MG FİLM KAPLI TABLET, 30 ADET ... LURADİN 60 MG FİLM KAPLI TABLET, 30 ADET …

Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and ... Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRAJENTA DUO 2.5MG/1000MG FILM KAPLI TABLET, 60 ADET ... TRAJENTA DUO 2.5MG/850MG FILM KAPLI TABLET, 60 ADET …

Acalabrutinib

To date, acalabrutinib has been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and Hodgkin lymphoma, among others. As of October 31, 2017 the FDA approved Astra Zeneca's orally administered Calquence (acalabrutinib, capsules). This Bruton tyrosine kinase (BTK) inhibitor indicated for the treatment of chronic...
Approved
Investigational
Matched Description: … been used in trials studying the treatment of B-All, myelofibrosis, ovarian cancer, multiple myeloma, and ... inhibitor indicated for the treatment of chronic lymphocytic leukemia, small lymphocytic lymphoma, and ... [L42795,L42800] Unlike Calquence capsules, the co-administration of Calquence tablets and PPIs does not …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … CALQUENCE 100 MG SERT KAPSÜL, 60 ADET …

Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigen

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Brisbane/60/2008 recombinant hemagglutinin antigen …
Matched Description: … There are two basic types of vaccines available: inactivated influenza vaccine (IIV) and live attenuated ... Upon re-exposure to infectious influenza virus, the immune system is prepared to identify and destroy ... includes the production of humoral immunity through the development of antibodies (through memory B cells) and …

Dexketoprofen

Dexketoprofen is a non-steroidal anti-inflammatory drug. It is available in the various countries in Europe, Asia and Latin America. It has analgesic, antipyretic and anti-inflammatory properties .
Approved
Investigational
Matched Description: … It is available in the various countries in Europe, Asia and Latin America. ... It has analgesic, antipyretic and anti-inflammatory properties [L1298]. …
Matched Mixtures name: … LEODEX PLUS % 1.25 + % 0.25 JEL, 60 G …
Matched Categories: … Propylene Glycols ... Alcohols ... Glycols ... Ketoprofen and isomer ... tramadol and dexketoprofen …
Matched Products: … ELEKTRA 1.25 JEL,60 G ... LEODEX %1,25 JEL 60 GR ... SERTOFEN %1.25 JEL,60 G …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … , embryo implantation, and the successful establishment of pregnancy. ... Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Gesterol In Oil-liq Im 50mg/ml …

Tolmetin

A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Approved
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … TOLECTIN KOMPRIME TABLET, 60 ADET …

Pimozide

A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome. Although the precise mechanism of action is unknown, blockade of postsynaptic dopamine receptors has been postulated. (From AMA Drug Evaluations Annual, 1994,...
Approved
Matched Description: … for the suppression of vocal and motor tics in patients with Tourette syndrome. ... A diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol …
Matched Products: … NOROFREN 2 MG TABLET, 60 ADET …

Sucralfate

Sucralfate is a medication that is widely used to prevent and treat a number of diseases in the gastrointestinal tract such as duodenal ulcers [FDA label], gastro-esophageal reflux disease (GERD), gastritis, peptic ulcer disease, stress ulcer, in addition to dyspepsia . It is considered a cytoprotective agent, protecting cells in...
Approved
Matched Description: … cells in the gastrointestinal tract from damage caused by agents such as gastric acid, bile salts, alcohol ... It is sold under many brands and is available in both tablet and suspension forms. ... Sucralfate has been shown to be a well-tolerated and safe drug. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … SUKRAT TABLET, 60 ADET ... ANTEPSIN 1 G TABLET, 60 ADET …

Streptococcus pneumoniae type 6a capsular polysaccharide antigen

Approved
Experimental
Matched Name: … Streptococcus pneumoniae type 6a capsular polysaccharide antigen …

Aminosalicylic acid

An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Salts cas: … 6059-16-1 ... 6018-19-5 …
Matched Categories: … Aminosalicylic Acid and Derivatives …
Matched Products: … MONOPAS®GRÁNULOS (PAS SODICO) 60% P/P …

Raltegravir

Raltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase inhibitors, to receive such approval.
Approved
Matched Description: … Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase …
Matched Categories: … lamivudine and raltegravir …
Matched Products: … ISENTRESS 400 MG FILM KAPLI TABLET, 60 ADET …

Etidronic acid

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid] ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and ... generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and …
Matched Categories: … etidronic acid and calcium, sequential ... Drugs Affecting Bone Structure and Mineralization …
Matched Products: … DIDRONAT 200 MG TABLET, 60 ADET …

Alteplase

Alteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent. It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots. In the absence of fibrin, the alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and fibrin.[A252330,L43125] Alteplase...
Approved
Investigational
Matched Synonyms: … Plasminogen activator (human tissue-type protein moiety) …
Matched Description: … alteplase-mediated conversion of plasminogen is limited, thanks to the high affinity between alteplase and ... thrombolytic agents derived from tissue plasminogen activator, such as [desmoteplase], [tenecteplase] and ... alteplase to manage AMI has decreased thanks to the availability of safer treatments such as angioplasty and …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... ), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... niraparib and abiraterone ... abiraterone and prednisolone ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … RATEBİR 250 MG TABLET, 60 ADET ... ABYGA 500 MG FİLM KAPLI TABLET, 60 ADET ... ZYTİGA 500 MG FİLM KAPLI TABLET, 60 ADET …

Eflornithine

Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... under the brand name IWILFIN as an oral maintenance therapy to reduce the risk of relapse in adult and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … EFLORİN %13.9 KREM, 60 GRAM …

Terfenadine

In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Approved
Withdrawn
Matched Products: … Seldane Tab 60mg ... Seldane - Tab 60mg ... TERFENADINA MK 60MG …

Loxoprofen

Loxoprofen is a propionic acid derivative non-steroidal anti-inflammatory drug. It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India, and as Oxeno in Argentina. A transdermal preparation was approved for use in Japan in January 2006.
Approved
Matched Description: … , and as Oxeno in Argentina. ... It is marketed under the trade name Loxonin in Brazil, Mexico and Japan by Sankyo, as Loxomac in India …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … LOXONIN 60 MG …

Apalutamide

Apalutamide is a potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and blocks AR nuclear translocation or binding to androgen response elements . It has been used in trials studying the treatment of Prostate Cancer, Hepatic Impairment, Prostatic Neoplasms, Castration-Resistant Prostate Cancer, and Prostatic...
Approved
Investigational
Matched Description: … It targets the AR ligand-binding domain and prevents AR nuclear translocation, DNA binding, and transcription ... risk for metastases and death [A31846]. ... potent androgen receptor (AR) antagonist that selectively binds to the ligand-binding domain of AR and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Matched Products: … ERLEADA FILM-COATED TABLET 60MG ... Erleada 60mg Film-Coated Tablets ... ERLEADA ®TABLETAS RECUBIERTAS 60 MG …

Sirolimus

Sirolimus, also known as rapamycin, is a macrocyclic lactone antibiotic produced by bacteria Streptomyces hygroscopicus, which was isolated from the soil of the Vai Atari region of Rapa Nui (Easter Island). It was first isolated and identified as an antifungal agent with potent anticandida activity; however, after its potent antitumor...
Approved
Investigational
Matched Description: … more attention especially in cancer, as mTOR signalling pathways are constitutively activated in many types ... extensively investigated as an immunosuppressive and antitumour agent. ... [A242412] It was first isolated and identified as an antifungal agent with potent anticandida activity …
Matched Categories: … Sirolimus and Prodrugs ... Antineoplastic and Immunomodulating Agents …
Matched Products: … RAPAMUNE 1 MG/ML 60 ML ORAL SOLUSYON …

Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate

Experimental
Matched Name: … Glycyl-L-a-Aminopimelyl-E-(D-2-Aminoethyl)Phosphonate …

Iothalamic acid

Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Categories: … Alcohols ... Sugar Alcohols …
Matched Products: … Conray 60 …

(R)-warfarin

Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways. S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.
Experimental
Matched Synonyms: … R,R-Warfarin alcohol …
Matched Description: … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared …
Matched Categories: … Warfarin and isomers …
Displaying drugs 851 - 875 of 1041 in total