Displaying drugs 851 - 875 of 931 in total
Anti-CD7 CAR T-cell therapy
Investigational
Matched Synonyms: … A chimeric antigen receptor (CAR) immunotherapy directed against the target protein CD7 …
Matched Name: … Anti-CD7 CAR T-cell therapy …
Matched Name: … Anti-CD7 CAR T-cell therapy …
CTX130
CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Investigational
Matched Synonyms: … Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Matched Description: … CTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen …
Idecabtagene vicleucel
Multiple myeloma is a cancer where plasma cells rapidly divide out of control. These cancerous cells generally express the B-cell maturation antigen, while it is rarely expressed on non-cancerous cells. Multiple myeloma is typically treated with an immunomodulatory agent like lenalidomide, a proteasome inhibitor like bortezomib, or an anti-CD38 monoclonal...
Approved
Matched Synonyms: … Anti-BCMA CAR T cell …
Matched Description: … therapy like [axicabtagene ciloleucel] and [brexucabtagene autoleucel]. ... [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from ... [L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy ... Receptors, Cytoplasmic and Nuclear …
Matched Description: … therapy like [axicabtagene ciloleucel] and [brexucabtagene autoleucel]. ... [A232558,A232563,L32858] These therapies involve extracting and genetically manipulating T-cells from ... [L32858] Idecabtagene vicleucel was approved by the FDA on March 26, 2021 [L32863] and by the EMA …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Antineoplastic cell and gene therapy ... Receptors, Cytoplasmic and Nuclear …
CAR BCMA-CS1
CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
Matched Name: … CAR BCMA-CS1 …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …
Matched Description: … B-cell maturation antigen and CS1. ... CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target …
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide …
Matched Description: … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus ... gratus and other plants of the Apocynaceae; used like digitalis. …
Matched Description: … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus ... gratus and other plants of the Apocynaceae; used like digitalis. …
Erythromycin
Erythromycin is a bacteriostatic antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and belongs to the macrolide group of antibiotics which consists of Azithromycin, Clarithromycin, Spiramycin and others. It was originally discovered in 1952. Erythromycin is widely used for treating a variety of infections, including those...
Approved
Investigational
Vet approved
Matched Description: … antibiotic drug produced by a strain of Saccharopolyspora erythraea (formerly Streptomyces erythraeus) and ... the macrolide group of antibiotics which consists of [Azithromycin], [Clarithromycin], [Spiramycin] and ... Erythromycin is widely used for treating a variety of infections, including those caused by gram-positive and …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … ERITROMICINA CARLO ERBA …
Matched Mixtures name: … Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin Ethylsuccinate and Sulfisoxazole Acetyl ... Erythromycin and Benzoyl Peroxide …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … ERITROMICINA CARLO ERBA …
3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid
Experimental
Matched Name: … 3-[(4-Carboxy-2-hydroxyphenyl)sulfamoyl]-2-thiophenecarboxylic acid …
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid …
Matched Iupac: … 3-[(4-carboxy-2-hydroxyphenyl)sulfamoyl]thiophene-2-carboxylic acid …
1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate
Experimental
Matched Name: … 1-(O-Carboxy-Phenylamino)-1-Deoxy-D-Ribulose-5-Phosphate …
METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE
Experimental
Matched Name: … METHYL(2-ACETOXY-2-(2-CARBOXY-4-AMINO-PHENYL))ACETATE …
3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium
Experimental
Matched Name: … 3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium …
Matched Iupac: … [(2R)-3-carboxy-2-(octanoyloxy)propyl]trimethylazanium …
Matched Iupac: … [(2R)-3-carboxy-2-(octanoyloxy)propyl]trimethylazanium …
Dutasteride
Dutasteride is an oral synthetic 4-azasteroid commonly marketed under the trade name Avodart. It is a novel dual 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and irreversible manner. Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary hormonal...
Approved
Investigational
Matched Synonyms: … α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide …
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... tamsulosin and dutasteride ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … hormonal mediator that plays a role in the development and enlargement of the prostate gland. ... 5α-reductase inhibitor that works by blocking both isoforms of 5α-reductase enzymes in a potent, selective, and ... [A1909] Type I and II 5α-reductase enzymes convert testosterone into dihydrotestosterone (DHT), a primary …
Matched Mixtures name: … Dutasteride and tamsulosin hydrochloride ... Dutasteride and Tamsulosin Hydrochloride ... Dutasteride and tamsulosin hydrochloride …
Matched Categories: … Genito Urinary System and Sex Hormones ... tamsulosin and dutasteride ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Haloperidol
Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently used antipsychotic medications used worldwide. While haloperidol has demonstrated pharmacologic activity at a number of receptors in the brain, it exerts its antipsychotic effect through its strong antagonism of the dopamine receptor (mainly D2), particularly within...
Approved
Matched Description: … Haloperidol is a high potency first-generation (typical) antipsychotic and one of the most frequently ... through its strong antagonism of the dopamine receptor (mainly D2), particularly within the mesolimbic and ... [F4645] It is also used off-label for the management of chorea associated with Huntington's disease and …
Matched Products: … ALOPERIDOLO CARLO ERBA …
Matched Products: … ALOPERIDOLO CARLO ERBA …
CTX110
CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen.
Investigational
Matched Synonyms: … allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Matched Description: … CTX110 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD19 antigen …
Fosgemcitabine palabenamide
NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
Investigational
Matched Synonyms: … 3R,5R)-5-(4-AMINO-2-OXO-PYRIMIDIN-1-YL)-4,4-DIFLUORO-3-HYDROXY-TETRAHYDROFURAN-2-YL)METHOXY-PHENOXY-PHOSPHORYL …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl]-L-tryptophanamide
Experimental
Matched Name: … Nα-[(2S)-2-{[(S)-[(1S)-1-{[(Benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]methyl}-5-phenylpentanoyl …
(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL]PROPANOIC ACID
Experimental
Matched Name: … (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-HYDROXY{(1R)-2-METHYL-1-[(PHENYLSULFONYL)AMINO]PROPYL}PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-benzenesulfonamido-2-methylpropyl](hydroxy)phosphoryl}propanoic …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-benzenesulfonamido-2-methylpropyl](hydroxy)phosphoryl}propanoic …
3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine
Experimental
Matched Name: … 3'-1-carboxy-1-phosphonooxy-ethoxy-uridine-diphosphate-N-acetylglucosamine …
Matched Iupac: … ,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl ... )oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-2-(phosphonooxy)propanoic …
Matched Iupac: … ,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl ... )oxy](hydroxy)phosphoryl}oxy)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-2-(phosphonooxy)propanoic …
4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID
Experimental
Matched Name: … 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID …
Matched Iupac: … 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-3-yl)benzoic acid …
Matched Iupac: … 4-(5-{[(2S)-1-carboxy-3-oxopropan-2-yl]carbamoyl}pyridin-3-yl)benzoic acid …
(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL]PROPANOIC ACID
Experimental
Matched Name: … (2S)-2-[3-(AMINOMETHYL)PHENYL]-3-[(R)-[(1R)-1-{[(BENZYLOXY)CARBONYL]AMINO}-2-METHYLPROPYL](HYDROXY)PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-methylpropyl](hydroxy)phosphoryl …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-methylpropyl](hydroxy)phosphoryl …
P-BCMA-101
P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Investigational
Matched Synonyms: … Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T …
Matched Description: … P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology. …
Matched Description: … P-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology. …
(2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL}PROPANOIC ACID
Experimental
Matched Name: … 2S)-2-[3-(AMINOMETHYL)PHENYL]-3-{(S)-HYDROXY[(1R)-2-METHYL-1-{[(2-PHENYLETHYL)SULFONYL]AMINO}PROPYL]PHOSPHORYL …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{hydroxy[(1R)-2-methyl-1-(2-phenylethanesulfonamido)propyl]phosphoryl …
Matched Iupac: … (2S)-2-[3-(aminomethyl)phenyl]-3-{hydroxy[(1R)-2-methyl-1-(2-phenylethanesulfonamido)propyl]phosphoryl …
Mefenamic acid
A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … VENIC FORTE …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … VENIC FORTE …
Cagrilintide
Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor).
Investigational
Matched Synonyms: … L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-γ-glutamyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-α-glutamyl-L-phenylalanyl-L-leucyl-L-arginyl-L-histidyl …
Matched Description: … investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
TPI-287
Investigational
Matched Synonyms: … (2'R,3'S)-2'-hydroxy-N-carboxy-3'-amino-5'-methyl-hexanoic,N-tert-butyl ester, 13 ester 5B-20-epoxy-1B …
Enalapril
Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Synonyms: … 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... enalapril and diuretics ... enalapril and nitrendipine …
Matched Description: … fluid and electrolyte homeostasis. ... the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and ... Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the …
Matched Mixtures name: … Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide ... Enalapril Maleate and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... enalapril and diuretics ... enalapril and nitrendipine …
Displaying drugs 851 - 875 of 931 in total