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Displaying drugs 851 - 875 of 3354 in total
Investigational
Matched Synonyms: … Pyridine, 4-(5-((1r)-1-(5-(3-chlorophenyl)-3-isoxazolyl)ethoxy)-4-methyl-4h-1,2,4-triazol-3-yl)- …
Matched Iupac: … 4-{5-[(1R)-1-[5-(3-chlorophenyl)-1,2-oxazol-3-yl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl}pyridine
Matched Categories: … Receptor, Metabotropic Glutamate 5, antagonists & inhibitors …
Experimental
Matched Synonyms: … Dipotassium hydrogen phosphate trihydrate …
Matched Name: … Potassium phosphate, dibasic, trihydrate …
Matched Iupac: … dipotassium trihydrate hydrogen phosphate
FM-VP4, is a novel hydrophilic phytostanol analogue representing a new class in cholesterol-lowering drugs called cholesterol absorption inhibitors. FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total cholesterol in a broad range of animal species. Additional experiments suggest that FM-VP4 can reduce plasma LDL...
Investigational
Matched Synonyms: … Disodium ascorbyl phytostanol phosphates
Matched Description: … FM-VP4 has been shown to inhibit cholesterol absorption and to lower plasma LDL-cholesterol and total ... levels, reduce weight gain and exert a anti-atherosclerosis effect. ... Additional experiments suggest that FM-VP4 can reduce plasma LDL cholesterol levels and triglyceride …
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Description: … A drug that has been used in various urinary syndromes and as an antispasmodic. ... Its therapeutic usefulness and its mechanism of action are not clear. ... It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity …
Matched Salts name: … Flavoxate hydrochloride
Matched Categories: … Drugs for Urinary Frequency and Incontinence ... Genito Urinary System and Sex Hormones …
Matched Products: … Flavoxate Hydrochloride
Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia).
Investigational
Matched Synonyms: … phosphate ... [2-amino-3-[3-[[4-(2-pyridyloxymethyl)phenyl]methyl]isoxazol-5-yl]pyridin-1-ium-1-yl]methyl hydrogen …
Matched Iupac: … amino-1-[(hydrogen phosphonatooxy)methyl]-3-[3-({4-[(pyridin-2-yloxy)methyl]phenyl}methyl)-1,2-oxazol-5- …
Matched Description: … Fosmanogepix is under investigation in clinical trial NCT03604705 (An Efficacy and Safety Study of APX001 …
Maprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs). Similar to TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and does not affect monoamine oxidase activity. It differs from TCAs in that it does not appear to block serotonin reuptake. Maprotiline may be used...
Approved
Investigational
Matched Description: … TCAs, maprotiline inhibits neuronal norepinephrine reuptake, possesses some anticholinergic activity, and ... be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and
Matched Salts name: … Maprotiline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Maprotiline Hydrochloride ... MAPROTILIN-NEURAX 50 MG ... Ludiomil 50 mg - Filmtabletten …
Experimental
Matched Name: … (C8-R)-hydantocidin 5'-phosphate
Matched Iupac: … (2R)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …
Experimental
Matched Synonyms: … Potassium sodium hydrogen citrate ... Sodium potassium hydrogen citrate …
Matched Name: … Potassium sodium hydrogen citrate …
Experimental
Matched Name: … 3'-Phosphate-Adenosine-5'-Diphosphate …
Matched Iupac: … [({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Experimental
Matched Name: … Pyridoxal-5'-Phosphate-N-Oxide …
Matched Iupac: … 4-formyl-3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-1-ium-1-olate …
Experimental
Matched Name: … 1-Deoxy-Ribofuranose-5'-Phosphate
Experimental
Matched Name: … (C8-S)-Hydantocidin 5'-phosphate
Matched Iupac: … (2S)-5-[(5S,7R,8S,9R)-8,9-dihydroxy-2,4-dioxo-7-[(phosphonooxy)methyl]-6-oxa-1,3-diazaspiro[4.4]nonan …
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807]. Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Salts cas: … 5144-52-5 ... 550-99-2 …
Matched Mixtures name: … Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate ... Naphazoline Hydrochloride and Pheniramine Maleate …
Matched Salts name: … Naphazoline hydrochloride
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Naphazoline Hydrochloride
Experimental
Matched Name: … 5-Bromo-2'-deoxyuridine 5'-(dihydrogen phosphate) …
Matched Iupac: … {[(2R,3S,5R)-5-(5-bromo-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic …
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine ... 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine …
Matched Description: … and other conditions. ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain …
Matched Salts name: … Nortriptyline hydrochloride
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …
Matched Products: … Nortriptyline Hydrochloride ... CIFLOXAL® 500 MG TABLETAS RECUBIERTAS …
Experimental
Matched Synonyms: … β-D-glucose 6-phosphate ... beta-D-glucose-6-phosphate ... beta-D-glucose 6-(dihydrogen phosphate) …
Matched Name: … beta-D-glucose 6-phosphate
Matched Iupac: … {[(2R,3S,4S,5R,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid …
EHT 0202 is developed to treat neurodegenerative disorders by ExonHit Therapeutics.
Investigational
Matched Synonyms: … 1H-PYRAZOLO(3,4-B)PYRIDINE-5-CARBOXYLIC ACID, 1-ETHYL-4-((1-METHYLETHYLIDENE)HYDRAZINO)-, ETHYL ESTER …
Experimental
Matched Synonyms: … α-D-mannose 6-phosphate ... alpha-D-Mannopyranose 6-phosphate
Matched Name: … alpha-D-mannose 6-phosphate
Matched Iupac: … {[(2R,3S,4S,5S,6S)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid …
Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme results in efficacious reduction of serum urate levels. Xanthine oxidase inhibitors are classified into two groups; purine analogs such as...
Experimental
Matched Synonyms: … 4-(5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile …
Matched Iupac: … 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile …
Matched Description: … and gout. ... ], and non-purine agents which includes topiroxostat. ... Uriadec and is orally administered twice daily. …
Experimental
Matched Synonyms: … Erythose-4-phosphate
Matched Name: … D-erythrose 4-phosphate
Experimental
Matched Synonyms: … dibutyryl adenosine 3',5'-cyclic phosphate ... dibutyryl-3',5'-AMP ... 3',5'-cyclic AMP dibutyrate …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Name: … N-Methyl-Pyridoxal-5'-Phosphate
Matched Iupac: … 4-formyl-3-hydroxy-1,2-dimethyl-5-[(phosphonooxy)methyl]pyridin-1-ium …
Experimental
Matched Name: … Alpha-Ribazole-5'-Phosphate Derivative …
Matched Iupac: … {[(2R,3S,4R,5S)-5-(1H-1,3-benzodiazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Experimental
Matched Name: … 4-Methyl-5-Hydroxyethylthiazole Phosphate
Matched Iupac: … [2-(4-methyl-1,3-thiazol-5-yl)ethoxy]phosphonic acid …
Experimental
Matched Name: … 3'-THIO-THYMIDINE-5'-PHOSPHATE
Matched Iupac: … {[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-sulfanyloxolan-2-yl]methoxy}phosphonic …
Displaying drugs 851 - 875 of 3354 in total