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Displaying drugs 851 - 875 of 2956 in total
3-Fluoro-L-tyrosine is a solid. This compound belongs to the phenylpropanoic acids. These are compounds whose structure contain a benzene ring conjugated to a propanoic acid. 3-Fluoro-L-tyrosine targets the protein superoxide dismutase [mn], mitochondrial.
Experimental
Matched Synonyms: … 3-fluoro-L-tyrosine
Matched Name: … 3-Fluoro-L-tyrosine
Matched Iupac: … (2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
Matched Description: … 3-Fluoro-L-tyrosine is a solid. This compound belongs to the phenylpropanoic acids. ... These are compounds whose structure contain a benzene ring conjugated to a propanoic acid. 3-Fluoro-L-tyrosine
Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN.
Investigational
Matched Synonyms: … -ASPARTYL-L-LEUCYL-L-SERYL-L-LYSYL-L-GLUTAMINYL-L-METHIONYL-L-.ALPHA.-GLUTAMYL-L-.ALPHA. ... -GLUTAMYL-L-.ALPHA.-GLUTAMYL-L-ALANYL-L-VALYL-L-ARGINYL-L-LEUCYL-L-PHE …
Matched Description: … Vurolenatide is a recombinant fusion protein comprising exenatide and XTEN. …
Experimental
Matched Synonyms: … 2-methyl-propionic acid ... iso-butyric acid ... 2-Methylpropanoic acid
Matched Name: … Isobutyric acid
Matched Iupac: … 2-methylpropanoic acid
Matched Categories: … Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Experimental
Matched Synonyms: … Ketomalonic acid ... Oxomalonic acid ... alpha-Ketomalonic acid
Matched Name: … Mesoxalic acid
Matched Iupac: … 2-oxopropanedioic acid
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids
An antitubercular agent often administered in association with isoniazid. The sodium salt of the drug is better tolerated than the free acid.
Approved
Matched Synonyms: … Aminosalicylic acid ... 4-aminosalicylic acid ... p-aminosalicylic acid
Matched Name: … Aminosalicylic acid
Matched Iupac: … 4-amino-2-hydroxybenzoic acid
Matched Description: … The sodium salt of the drug is better tolerated than the free acid. …
Matched Categories: … Aminosalicylic Acid and Derivatives ... Acids, Carbocyclic ... Hydroxy Acids ... Carboxylic Acids ... Aminosalicylic Acids
Polycythemia vera (PV) is the most common Philadelphia chromosome-negative myeloproliferative neoplasm (MPN), characterized by increased hematocrit and platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term propensity for myelofibrosis and leukemia.[A242000, A242005] Interferon alfa-2b has been used for decades to treat PV but requires frequent dosing...
Approved
Investigational
Matched Synonyms: … Pegylated proline interferon alpha-2b ... Pegylated proline-interferon alpha-2b …
Matched Description: … A242005] Ropeginterferon alfa-2b is a next-generation mono-pegylated type I interferon produced from proline-IFN-α ... platelet/leukocyte counts, an increased risk for hemorrhage and thromboembolic events, and a long-term ... propensity for myelofibrosis and leukemia. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol ... [A10367] It is further classified as a second-generation progestin, along with [levonorgestrel] and its ... endometriosis, and was not marketed for use as an oral contraceptive until 1962. …
Matched Mixtures name: … Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate
Matched Salts name: … Norethisterone acetate
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Pituitary and Hypothalamic Hormones and Analogues ... Genito Urinary System and Sex Hormones ... Sex Hormones and Insulins ... norethisterone and estrogen …
Matched Products: … Norethindrone Acetate ... Norethindrone acetate
Experimental
Matched Synonyms: … Sulfocarbolic acid ... Phenolsulfonic acid ... p-Phenolsulfonic acid
Matched Name: … Phenolsulfonic acid
Matched Iupac: … 4-hydroxybenzene-1-sulfonic acid
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist.[Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid...
Approved
Matched Synonyms: … N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide ... N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide …
Matched Description: … Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as ... [A6932] Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer ... for lysine at position 34. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism ... insulin degludec and liraglutide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Experimental
Matched Synonyms: … 4-coumaric acid ... p-Coumaric acid ... (E)-p-coumaric acid
Matched Name: … p-Coumaric acid
Matched Iupac: … (2E)-3-(4-hydroxyphenyl)prop-2-enoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … Procaine ... 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Name: … Procaine
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. ... Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients …
Matched Salts name: … Procaine nitrate ... Procaine phosphate ... Procaine hydrochloride …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Acids, Carbocyclic ... Carboxylic Acids ... Esters of Aminobenzoic Acid ... procaine
Matched Products: … Procaine Hydrochloride …
Experimental
Matched Synonyms: … (3-(N-Hydroxy)carboxamido-2-benzylpropanoyl)alanine
Matched Iupac: … (2S)-2-[(2R)-2-benzyl-3-(hydroxycarbamoyl)propanamido]propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins …
Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … L-TYROSINE, L-CYSTEINYL-L-CYSTEINYL-L-.ALPHA. ... -GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL ... (9-L-TYROSINE)HEAT-STABLE ENTEROTOXIN (ESCHERICHIA COLI)-(6-19)-PEPTIDE …
Matched Iupac: … dodecaazatetracyclo[22.22.4.2^{16,33}.0^{7,11}]dopentacontan-38-yl]formamido}-3-(4-hydroxyphenyl)propanoic acid
Matched Description: … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide …
Matched Salts name: … Linaclotide acetate
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Experimental
Matched Synonyms: … Ethylenesulfonic acid ... Vinylsulphonic acid
Matched Name: … Vinylsulfonic acid
Matched Iupac: … ethenesulfonic acid
Matched Categories: … Acids ... Sulfur Acids ... Acids, Noncarboxylic …
Experimental
Matched Synonyms: … Quingestanol acetate ... Norethindrone acetate 3-cyclopentyl enol ether …
Matched Name: … Quingestanol acetate
Matched Iupac: … )-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate
Delpacibart is a humanized, bispecific, bivalent monoclonal antibody against coagulation factor 9.
Investigational
Matched Synonyms: … Immunoglobulin G4 [230-proline,de-449-lysine], anti-(human blood-coagulation factor IX) (human clone …
Ovemotide is under investigation in clinical trial NCT00357461 (Ipilimumab With or Without Vaccine Therapy in Treating Patients With Previously Treated Stage IV Melanoma).
Investigational
Matched Synonyms: … L-valine, l-tyrosyl-l-leucyl-l-.alpha.-glutamyl-l-prolylglycyl-l-prolyl-l-valyl-l-threonyl- ... (264-l-valine)melanocyte protein pmel 17 (human melanoma-associated me20 antigen)-(256-264)-peptide …
Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and Change in Disease Activity of 24-hour Continuous Subcutaneous Infusion of ABBV-951 in Adult Participants With Advanced Parkinson's Disease).
Approved
Investigational
Matched Synonyms: … 3-hydroxy-O-phosphono-L-tyrosine
Matched Iupac: … (2S)-2-amino-3-[3-hydroxy-4-(phosphonooxy)phenyl]propanoic acid
Matched Description: … Foslevodopa is under investigation in clinical trial NCT04750226 (Study to Assess Adverse Events and
Matched Categories: … Dopa and Dopa Derivatives ... foslevodopa and decarboxylase inhibitor …
Oxogluric acid (α-Ketoglutarate) is not approved for any indication in the world but is an investigational drug in the United States. In the United States a phase I clinical trial is investigating whether oxogluric acid precursors found in nutritional supplements can benefit patients with the metabolic disorder propionic acidemia. Oxogluric...
Experimental
Investigational
Nutraceutical
Matched Synonyms: … 2-Ketoglutaric acid ... 2-oxoglutaric acid ... Ketoglutaric acid
Matched Name: … Oxogluric acid
Matched Iupac: … 2-oxopentanedioic acid
Matched Description: … reactions during the metabolism of amino acids, forms glutamic acid by combining with ammonia, and reduces ... remove excess ammonia, but it is not officially approved for this indication and only experimental studies ... have shown a reduction in ammonia by oxogluric acid in hemodialysis patients. …
Matched Categories: … Acids, Acyclic ... Keto Acids ... Carboxylic Acids ... Dicarboxylic Acids ... Ketoglutaric Acids
Investigational
Matched Synonyms: … Dimebutic acid ... 2,2-dimethylbutanoic acid ... 2,2-dimethylbutyric acid
Matched Iupac: … 2,2-dimethylbutanoic acid
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Experimental
Matched Synonyms: … Aspartyl adenylate …
Matched Name: … Adenylosuccinic acid
Matched Iupac: … 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Nucleic Acids, Nucleotides, and Nucleosides ... Amino Acids, Acidic ... Amino Acids ... Excitatory Amino Acids
Experimental
Matched Synonyms: … (−)-mandelic acid ... (−)-(R)-mandelic acid ... D-mandelic acid
Matched Name: … (R)-Mandelic acid
Matched Iupac: … (2R)-2-hydroxy-2-phenylacetic acid
Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).
Investigational
Matched Synonyms: … Phorbol myristate acetate ... Tetradecanoylphorbol acetate ... Phorbol 12-myristate 13-acetate
Matched Name: … Phorbol 12-myristate 13-acetate diester …
Matched Description: … Phorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs). …
Investigational
Matched Synonyms: … Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15 …
Experimental
Matched Synonyms: … 2-Mercaptobenzoic acid ... 2-Thiosalicylic acid ... 2-Sulfanylbenzoic acid
Matched Name: … Thiosalicylic acid
Matched Iupac: … 2-sulfanylbenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids
Displaying drugs 851 - 875 of 2956 in total