Displaying drugs 8751 - 8775 of 11935 in total
SSR-126517E
SSR-126517E is a second generation synthetic pentasaccharide that binds antithrombin with such high affinity that it assumes a plasma half-life of 80 hours.
Investigational
Indium In-111
Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).
Investigational
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Endothelin 1 (pig) ... Endothelin 1 (rat) ... Endothelin 1 (human) …
Matched Name: … Endothelin-1 …
Matched Description: … Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation …
Matched Categories: … Endothelin-1, antagonists & inhibitors …
Matched Name: … Endothelin-1 …
Matched Description: … Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation …
Matched Categories: … Endothelin-1, antagonists & inhibitors …
Fluorine F-18
Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions).
Investigational
Reversin 121
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.
Experimental
Matched Iupac: … tert-butyl (2S)-2-[(2S)-4-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}-4-oxobutanamido]-6-{[(benzyloxy …
Gold cation (1+)
Experimental
Matched Synonyms: … Gold(1+) ... Gold ion(1+) ... Gold(1+) ion …
Matched Name: … Gold cation (1+) …
Matched Iupac: … gold(1+) ion …
Matched Name: … Gold cation (1+) …
Matched Iupac: … gold(1+) ion …
GX-19 Vaccine
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Synonyms: … DNA vaccine expressing SARS-CoV-2 S-protein antigen …
SMART101
SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
Investigational
Trifluoroethanol
A non-aqueous co-solvent that serves as tool to study protein folding. It is also used in various pharmaceutical, chemical and engineering applications.
Experimental
Matched Iupac: … 2,2,2-trifluoroethan-1-ol …
Vintafolide
Vintafolide is a folate-targeted chemotherapeutic conjugate (folate vitamin + vinca alkaloid) in clinical stage development as a treatment for folate-receptor positive cancers.
Investigational
Matched Iupac: … -4-carbamimidamido-1-{[(1S)-2-carboxy-1-{[(1S)-2-carboxy-1-{[(1R)-1-carboxy-2-{[2-({N'-[(1R,9R,10S,11R ... (2S)-2-[(4-{[(2-amino-4-oxo-4,8-dihydropteridin-6-yl)methyl]amino}phenyl)formamido]-4-{[(1S)-1-{[(1S) ... hydrazinecarbonyl}oxy)ethyl]disulfanyl}ethyl]carbamoyl}ethyl]carbamoyl}ethyl]carbamoyl}butyl]carbamoyl}-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
4-methylumbelliferyl beta-D-glucoside
Experimental
Matched Synonyms: … 7-(beta-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one …
Matched Iupac: … 4-methyl-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-methyl-7-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-2H-chromen-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
ATL1102
ATL1102 is a second-generation antisense inhibitor of CD49d, an immunesystem protein known as VLA-4, an immune cell molecule. It works by entering cells and targeting genes.
Investigational
GMX1777
GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa...
Investigational
Bryostatin 1
Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Investigational
Matched Synonyms: … Bryostatin-1 …
Matched Name: … Bryostatin 1 …
Matched Iupac: … ]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1 ... ^{3,7}.1^{11,15}]nonacos-8-en-12-yl (2E,4E)-octa-2,4-dienoate ... (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl …
Matched Description: … Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. …
Matched Name: … Bryostatin 1 …
Matched Iupac: … ]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1 ... ^{3,7}.1^{11,15}]nonacos-8-en-12-yl (2E,4E)-octa-2,4-dienoate ... (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl …
Matched Description: … Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. …
JHU-75528 C-11
JHU-75528 C-11 is under investigation in clinical trial NCT03204305 (Brain Imaging of Cannabinoid Receptors).
Investigational
Matched Iupac: … 4-cyano-1-(2,4-dichlorophenyl)-5-[4-(11C)methoxyphenyl]-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide …
HQP1351
HQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).
Investigational
Matched Iupac: … 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{1H-pyrazolo[3,4-b]pyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CAR BCMA-CS1
CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
ANG1005
Investigational
CT103A
CT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.
Investigational
[2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala
Experimental
Matched Name: … [2(R,S)-2-Sulfanylheptanoyl]-Phe-Ala …
Matched Iupac: … (2S)-2-[(2S)-3-phenyl-2-[(2S)-2-sulfanylheptanamido]propanamido]propanoic acid …
Matched Iupac: … (2S)-2-[(2S)-3-phenyl-2-[(2S)-2-sulfanylheptanamido]propanamido]propanoic acid …
Fostroxacitabine bralpamide
Investigational
Matched Iupac: … (2S)-pentan-2-yl (2S)-2-{[(S)-{[(2S,4S)-4-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-1,3-dioxolan-2-yl …
10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Iupac: … (2S)-2-({4-[(1S)-2-(2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)-1-carboxyethyl]phenyl}formamido)pentanedioic …
Anhydrovinblastine
Anhydrovinblastine has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific.
Investigational
Matched Iupac: … 13-yl]-10-hydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2( …
7-methyl-7,8-dihydroguanosine-5'-diphosphate
Experimental
Matched Iupac: … -2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid ... [({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-hydroxy-2-imino-7-methyl-3,7,8,9-tetrahydro-2H-purin-9-yl)oxolan …
ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE
Experimental
Matched Name: … ETHYL 4-[(4-CHLOROPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE …
Matched Iupac: … ethyl 4-[(4-chloropyridin-2-yl)amino]piperidine-1-carboxylate …
Matched Iupac: … ethyl 4-[(4-chloropyridin-2-yl)amino]piperidine-1-carboxylate …
Displaying drugs 8751 - 8775 of 11935 in total