Displaying drugs 8776 - 8800 of 9659 in total
Nocodazole
Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
Experimental
Matched Iupac: … methyl N-[5-(thiophene-2-carbonyl)-1H-1,3-benzodiazol-2-yl]carbamate …
Trapidil
Trapidil, a platelet-derived growth factor antagonist, was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
Experimental
Matched Iupac: … N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine …
Pidotimod
Pidotimod is a synthetic dipeptide with immunomodulatory properties.
Experimental
Matched Iupac: … (4R)-3-[(2S)-5-oxopyrrolidine-2-carbonyl]-1,3-thiazolidine-4-carboxylic acid …
Lisofylline
Lisofylline has been investigated for the treatment of Type 1 Diabetes Mellitus.
Investigational
Matched Iupac: … 1-[(5R)-5-hydroxyhexyl]-3,7-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
AKN-028
AKN-028 has been used in trials studying the treatment of Acute Myeloid Leukemia.
Investigational
Matched Iupac: … N2-(1H-indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine …
Ripasudil
Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension. It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the...
Experimental
Matched Iupac: … 4-fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline …
Fabomotizole
Experimental
Matched Iupac: … 5-ethoxy-2-{[2-(morpholin-4-yl)ethyl]sulfanyl}-1H-1,3-benzodiazole …
Cannabigerol
A natural product found in Cannabis sativa and Helichrysum species.
Experimental
Matched Iupac: … 2-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-5-pentylbenzene-1,3-diol …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Carbaphosphonate
Experimental
Matched Iupac: … (1S,3R,4R,5S)-1,3,4-trihydroxy-5-(phosphonomethyl)cyclohexane-1-carboxylic acid …
N-Acetylmannosaminitol
Experimental
Matched Iupac: … (2R,3S,4R,5R)-5-{[(1S)-1-hydroxyethyl]amino}hexane-1,2,3,4,6-pentol …
Indeglitazar
Experimental
Matched Iupac: … 3-[5-methoxy-1-(4-methoxybenzenesulfonyl)-1H-indol-3-yl]propanoic acid …
Clorexolone
Experimental
Matched Iupac: … 6-chloro-2-cyclohexyl-3-oxo-2,3-dihydro-1H-isoindole-5-sulfonamide …
Emopamil
Prevents renal injury after warm & cold ischemia.
Experimental
Matched Iupac: … 5-[methyl(2-phenylethyl)amino]-2-phenyl-2-(propan-2-yl)pentanenitrile …
Vercirnon
Vercirnon is a novel, orally active anti-inflammatory agent that targets a chemokine receptor protein implicated in both Crohn's disease and ulcerative colitis, the two principal forms of IBD. It is under investigation in clinical trial NCT01611805 (Japanese Phase I of GSK1605786).
Investigational
Matched Iupac: … 4-[2-(4-tert-butylbenzenesulfonamido)-5-chlorobenzoyl]pyridin-1-ium-1-olate …
Chromium histidinate
Investigational
Matched Iupac: … chromium(3+) tris((2S)-2-amino-3-(1H-imidazol-5-yl)propanoate) …
Tacalcitol
Experimental
Investigational
Matched Iupac: … -4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol ... (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-octahydro-1H-inden …
Matched Products: … Curatoderm 4 Mikrogramm/g - Emulsion zur Anwendung auf der Haut …
Matched Products: … Curatoderm 4 Mikrogramm/g - Emulsion zur Anwendung auf der Haut …
Aclarubicin
Investigational
Matched Iupac: … methyl (1R,2R,4S)-4-{[(2R,4S,5S,6S)-4-(dimethylamino)-5-{[(2S,4S,5S,6S)-4-hydroxy-6-methyl-5-{[(2R,6S ... )-6-methyl-5-oxooxan-2-yl]oxy}oxan-2-yl]oxy}-6-methyloxan-2-yl]oxy}-2-ethyl-2,5,7-trihydroxy-6,11-dioxo …
Tolrestat
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications. While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was sold under the tradename...
Withdrawn
Matched Iupac: … 2-{1-[6-methoxy-5-(trifluoromethyl)naphthalen-1-yl]-N-methylmethanethioamido}acetic acid …
7-Deaza-7-Aminomethyl-Guanine
Experimental
Matched Iupac: … 2-amino-5-(aminomethyl)-3H,4H,7H-pyrrolo[2,3-d]pyrimidin-4-one …
N-acetyl-D-glucosamine-6-phosphate
Experimental
Matched Iupac: … {[(2R,3S,4R,5R)-5-acetamido-3,4,6-trihydroxyoxan-2-yl]methoxy}phosphonic acid …
Coelenteramide
Experimental
Matched Iupac: … N-[3-benzyl-5-(4-hydroxyphenyl)pyrazin-2-yl]-2-(4-hydroxyphenyl)acetamide …
MK-0354
MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis and related disorders. It targets G protein-coupled receptor, or GPCR, that have the potential to regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of niacin.
Investigational
Matched Iupac: … 5-{1H,4H,5H,6H-cyclopenta[c]pyrazol-3-yl}-2H-1,2,3,4-tetrazole …
Losmapimod
Losmapimod has been investigated for the prevention of Chronic Obstructive Pulmonary Disease.
Investigational
Matched Iupac: … 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide …
Displaying drugs 8776 - 8800 of 9659 in total