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Displaying drugs 8901 - 8925 of 11340 in total
Isatin
Isatin is an indole derivative first obtained by Erdman and Laurent in 1841 as an oxidation product of Indigo dye with nitric acid and chromic acids. The compound is found in many plants and Schiff bases of Isatin are have been investigated for pharmaceutical applications.
Experimental
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Mezagitamab
Mezagitamab is under investigation in clinical trial NCT04278924 (Study to Evaluate Safety, Tolerability, and Efficacy of TAK-079 in Participants With Persistent/chronic Primary Immune Thrombocytopenia).
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1-LAMBDA, ANTI-(HOMO SAPIENS ADP-RIBOSYL CYCLASE/CYCLIC ADP-RIBOSE HYDROLASE 1 (2'-PHOSPHO-ADP-RIBOSYL …
Dimethyltryptamine
An N-methylated indoleamine derivative, a serotonergic hallucinogen found in several plants, especially Prestonia amazonica (Apocynaceae) and in mammalian brain, blood, and urine. It apparently acts as an agonist at some types of serotonin receptors and an antagonist at others.
Experimental
Illicit
Matched Synonyms: … 2-(3-indolyl)ethyldimethylamine ... 3-(2-dimethylaminoethyl)indole ... 3-[2-(dimethylamino)ethyl]indole …
Matched Iupac: … [2-(1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … [2-(1H-indol-3-yl)ethyl]dimethylamine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Hydroxypropyl betadex
Hydroxypropyl betadex is under investigation in clinical trial NCT03471143 (Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C).
Investigational
Matched Synonyms: … 2-Hydroxypropyl-b-cyclodextrin ... 2-Hydroxylpropyl-beta-cyclodextrin ... 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN …
Matched Iupac: … [31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontane-36,37,38,39,41,42,43,45,46,48 ... 36R,37R,38R,39R,40R,41R,42R,43R,45R,46S,47R,48S,49R)-5,10,25,35-tetrakis(hydroxymethyl)-40,47,49-tris(2- ... hydroxypropoxy)-15,20,30-tris[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo …
Matched Iupac: … [31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontane-36,37,38,39,41,42,43,45,46,48 ... 36R,37R,38R,39R,40R,41R,42R,43R,45R,46S,47R,48S,49R)-5,10,25,35-tetrakis(hydroxymethyl)-40,47,49-tris(2- ... hydroxypropoxy)-15,20,30-tris[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo …
Penimepicycline
Penimepicycline is a tetracycline-class antibiotic. It is mentioned on List A produced by the Government of Canada, which is a list of antimicrobial active pharmaceutical ingredients . In the classification of the active ingredients included on this list, the classification document states that tetracycline class antibiotics are of medium importance,...
Experimental
Matched Iupac: … ; (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-N-{[4-(2-hydroxyethyl)piperazin-1 ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid ... -yl]methyl}-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Toralizumab
Toralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
Investigational
Carbazochrome
Carbazochrome is a hemostatic agent that promotes clotting, preventing blood loss from open wounds. It is an oxidation product of adrenaline which enhances the microcirculatory tone . In the future this may prevent excessive blood flow during surgical operations and the treatment of hemorrhoids, but research on effectiveness and severity...
Experimental
Withdrawn
Matched Iupac: … {[(5Z)-3-hydroxy-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indol-5-ylidene]amino}urea …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Avizakimab
Avizakimab is under investigation in clinical trial NCT03371251 (Study of BOS161721 in Systemic Lupus Erythematosus (SLE) Patients on a Background of Limited Standard of Care).
Investigational
Technetium TC-99M trofolastat
Investigational
Matched Synonyms: … -glutamyl-n6,n6-bis((1-(2-(bis(carboxymethyl)amino)-2-oxoethyl)-1h-imidazol-2-yl-.kappa.n3)methyl)-l-lysine …
Tralesinidase alfa
Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.
Investigational
Matched Synonyms: … Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein ... Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2 …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
Matched Description: … fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. …
2-Dimethylamino-Ethyl-Diphosphate
Experimental
Matched Name: … 2-Dimethylamino-Ethyl-Diphosphate …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Matched Iupac: … ({[2-(dimethylamino)ethoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
(R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol
Experimental
Matched Name: … (R)-1-Para-Nitro-Phenyl-2-Azido-Ethanol …
Matched Iupac: … (1R)-2-azido-1-(4-nitrophenyl)ethan-1-ol …
Matched Iupac: … (1R)-2-azido-1-(4-nitrophenyl)ethan-1-ol …
3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE
Experimental
Matched Name: … 3-(1H-BENZIMIDAZOL-2-YL)-1H-INDAZOLE …
Matched Iupac: … 3-(1H-1,3-benzodiazol-2-yl)-1H-indazole …
Matched Iupac: … 3-(1H-1,3-benzodiazol-2-yl)-1H-indazole …
3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE
Experimental
Matched Name: … 3-(1-NAPHTHYLMETHOXY)PYRIDIN-2-AMINE …
Matched Iupac: … 3-[(naphthalen-1-yl)methoxy]pyridin-2-amine …
Matched Iupac: … 3-[(naphthalen-1-yl)methoxy]pyridin-2-amine …
9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE
Experimental
Matched Name: … 9-CYCLOPENTYL-6-[2-(3-IMIDAZOL-1-YL-PROPOXY)-PHENYLAMINO]-9H-PURINE-2-CARBONITRILE …
Matched Iupac: … 9-cyclopentyl-6-({2-[3-(1H-imidazol-1-yl)propoxy]phenyl}amino)-9H-purine-2-carbonitrile …
Matched Iupac: … 9-cyclopentyl-6-({2-[3-(1H-imidazol-1-yl)propoxy]phenyl}amino)-9H-purine-2-carbonitrile …
ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
Experimental
Matched Name: … ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate …
Matched Iupac: … ethyl 3-[(1E)-2-amino-1-cyanoeth-1-en-1-yl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate …
Matched Iupac: … ethyl 3-[(1E)-2-amino-1-cyanoeth-1-en-1-yl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate …
(S)-Mandelic acid
Experimental
Matched Synonyms: … (S)-2-Hydroxy-2-phenylacetic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylacetic acid …
Matched Iupac: … (2S)-2-hydroxy-2-phenylacetic acid …
Serelaxin
Recombinant human relaxin is a hormone produced during pregnancy that facilitates the birth process by causing a softening and lengthening of the cervix and the pubic symphysis (the place where the pubic bones come together).It is a heterodimer protein secreted by the corpus luteum and placenta during pregnancy.
Investigational
Matched Synonyms: … Human relaxin 2 (relaxin h2) …
Seliciclib
R-roscovitine (Seliciclib or CYC202) is a cyclin-dependent kinase (CDK) inhibitor that preferentially inhibits multiple enzyme targets including CDK2, CDK7 and CDK9, which alter the growth phase of treated cells. Developed by Cyclacel, seliciclib is being researched for the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex...
Investigational
Matched Synonyms: … 2-(R)-(1-ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
1-Naphthyl-L-alanine
Experimental
Matched Synonyms: … Naphthalen-2-yl-3-alanine ... (S)-2-Amino-3-(naphthalen-1-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(naphthalen-1-yl)propanoic acid …
Nifekalant
Nifekalant is under investigation in clinical trial NCT03855826 (Evaluation of the Efficacy and Safety of Nifekalant Hydrochloride (NIF) Injection).
Investigational
Matched Synonyms: … 6-((2-((2-Hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyluracil …
Matched Iupac: … 6-({2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine …
Matched Iupac: … 6-({2-[(2-hydroxyethyl)[3-(4-nitrophenyl)propyl]amino]ethyl}amino)-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine …
Pegozafermin
Pegozafermin is under investigation in clinical trial NCT05852431 (To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia).
Investigational
2-(1H-pyrazol-3-yl)-1H-benzimidazole
Experimental
Matched Name: … 2-(1H-pyrazol-3-yl)-1H-benzimidazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
Matched Iupac: … 2-(1H-pyrazol-3-yl)-1H-1,3-benzodiazole …
N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
Experimental
Matched Name: … N-(3-AMINOPROPYL)-2-NITROBENZENAMINE …
Matched Iupac: … N1-(2-nitrophenyl)propane-1,3-diamine …
Matched Iupac: … N1-(2-nitrophenyl)propane-1,3-diamine …
Methyl salicylate 2-ethylbutyrate
Experimental
Matched Synonyms: … Salicylic acid, methyl ester, 2-ethylbutyrate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …
Matched Name: … Methyl salicylate 2-ethylbutyrate …
Matched Iupac: … methyl 2-[(2-ethylbutanoyl)oxy]benzoate …
Displaying drugs 8901 - 8925 of 11340 in total