Displaying drugs 876 - 900 of 2182 in total
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Iupac: … N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide …
Matched Categories: … Benzamides and benzamide derivatives …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... , where 82.3% and 77.5% of patients experienced a sustained hemoglobin improvement without transfusions …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... , where 82.3% and 77.5% of patients experienced a sustained hemoglobin improvement without transfusions …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Esmolol
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … (±)-methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... methyl p-(2-hydroxy-3-(isopropylamino)propoxy)hydrocinnamate ... Methyl 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)benzenepropanoate …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Matched Iupac: … methyl 3-(4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)propanoate …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. …
Methoxy arachidonyl fluorophosphonate
Methoxy arachidonyl fluorophosphonate, commonly referred as MAFP, is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and serine proteases. It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values in the low-nanomolar range.
Experimental
Matched Synonyms: … Methyl arachidonylfluorophosphonate …
Matched Iupac: … (S)-(methyl [(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]phosphonofluoridate) …
Matched Description: … is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and ... It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values …
Matched Iupac: … (S)-(methyl [(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraen-1-yl]phosphonofluoridate) …
Matched Description: … is an irreversible active site-directed enzyme inhibitor that inhibits nearly all serine hydrolases and ... It inhibits phospholipase A2 and fatty acid amide hydrolase with special potency, displaying IC50 values …
7-methyl-guanosine-5'-triphosphate-5'-guanosine
Experimental
Matched Synonyms: … mRNA cap analog N7-Methyl GpppG …
Matched Name: … 7-methyl-guanosine-5'-triphosphate-5'-guanosine …
Matched Iupac: … )-3,4-dihydroxyoxolan-2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl …
Matched Name: … 7-methyl-guanosine-5'-triphosphate-5'-guanosine …
Matched Iupac: … )-3,4-dihydroxyoxolan-2-yl]-7-methyl-6-oxo-6,7-dihydro-3H-9lambda5-purin-9-ylium ... dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)(hydroxy)phosphoryl]oxy}methyl …
9-(2-carboxyethyl)-10-methylanthracene endoperoxide
Experimental
Matched Synonyms: … [2'-CARBOXYLETHYL]-10-METHYL-ANTHRACENE ENDOPEROXIDE …
Matched Iupac: … 3-[(1s,8s)-8-methyl-15,16-dioxatetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaen-1- …
Matched Iupac: … 3-[(1s,8s)-8-methyl-15,16-dioxatetracyclo[6.6.2.0^{2,7}.0^{9,14}]hexadeca-2,4,6,9(14),10,12-hexaen-1- …
Plumbagin
Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.
Investigational
Matched Synonyms: … 5-hydroxy-2-methyl-1,4-naphthalenedione …
Matched Iupac: … 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102] …
Matched Iupac: … 5-hydroxy-2-methyl-1,4-dihydronaphthalene-1,4-dione …
Matched Description: … It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102] …
Imidacloprid
Imidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and sold under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and Winner. It is marketed as pest...
Vet approved
Matched Synonyms: … 1-((6-chloro-3-Pyridyl)methyl)-N-nitro-2-imidazolidinimine ... 1-((6-chloro-3-Pyridinyl)methyl)-N-nitro-2-imidazolidinimine ... (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine …
Matched Iupac: … 2-chloro-5-{[2-(nitroamino)-4,5-dihydro-1H-imidazol-1-yl]methyl}pyridine …
Matched Description: … Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and ... under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and ... It is marketed as pest control, seed treatment, an insecticide spray, termite control, flea control, and …
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Matched Iupac: … 2-chloro-5-{[2-(nitroamino)-4,5-dihydro-1H-imidazol-1-yl]methyl}pyridine …
Matched Description: … Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and ... under trade names Kohinor, Admire, Advantage, Gaucho, Merit, Confidor, Hachikusan, Premise, Prothor, and ... It is marketed as pest control, seed treatment, an insecticide spray, termite control, flea control, and …
Matched Mixtures name: … Advocate Spot-on Solution for Small Cats and Ferrets …
Hydronidone
Hydronidone has antifibrotic activity.
Investigational
Matched Synonyms: … N-(4-Hydroxyphenyl)-5-methyl-2-pyridone …
Matched Iupac: … 1-(4-hydroxyphenyl)-5-methyl-1,2-dihydropyridin-2-one …
Matched Iupac: … 1-(4-hydroxyphenyl)-5-methyl-1,2-dihydropyridin-2-one …
(2S)-2-Methyl-3-phenylpropanoic acid
Experimental
Matched Synonyms: … Deamino-methyl-phenylalanine …
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Matched Name: … (2S)-2-Methyl-3-phenylpropanoic acid …
Matched Iupac: … (2S)-2-methyl-3-phenylpropanoic acid …
Methylpropylpropanediol dinitrate
Experimental
Matched Synonyms: … 2-methyl-2-propylpropane-1,3-diyl dinitrate …
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …
Matched Iupac: … 2-methyl-1-(nitrooxy)-2-[(nitrooxy)methyl]pentane …
Iodoform
Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. It is a relatively water-insoluble yellow solid that is chemically reactive in free-radical reactions . Due to its antimicrobial properties following topical administration, minimal levels of iodoform may be found in disinfectants and it is more...
Approved
Experimental
Vet approved
Matched Synonyms: … methyl triiodide …
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. ... dressing or powder for wounds and sores, however such clinical use to this date is limited. ... properties following topical administration, minimal levels of iodoform may be found in disinfectants and …
Matched Description: … Iodoform is an organoiodine compound with the formula CHI3 and a tetrahedral molecular geometry. ... dressing or powder for wounds and sores, however such clinical use to this date is limited. ... properties following topical administration, minimal levels of iodoform may be found in disinfectants and …
Enmetazobactam
Enmetazobactam is a penicillanic acid sulfone extended-spectrum beta (β)-lactamase (ESBL) inhibitor. Because ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and monobactams, ESBL-producing bacteria poses challenges in the treatment of serious infections. The combination product of enmetazobactam and cefepime was first approved by the FDA on February...
Approved
Matched Synonyms: … -3-yl)methyl)-1-methyl-, inner salt ... (2s,3s,5r)-3-methyl-3-((3-methyltriazol-3-ium-1-yl)methyl)-4,4,7-trioxo-4^6-thia-1-azabicyclo(3.2.0)heptane ... 1h-1,2,3-triazolium, 3-(((2s,3s,5r)-2-carboxy-3-methyl-4,4-dioxido-7-oxo-4-thia-1-azabicyclo(3.2.0)hept …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl ... }-3-methyl-1H-1,2,3-triazol-3-ium …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
Matched Iupac: … 1-{[(2S,3S,5R)-2-carboxylato-3-methyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptan-3-yl]methyl ... }-3-methyl-1H-1,2,3-triazol-3-ium …
Matched Description: … ESBL enzymes can hydrolyze important antibiotics such as penicillins, broad-spectrum cephalosporins and ... [A263276] The combination product of enmetazobactam and [cefepime] was first approved by the FDA …
(3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime
Experimental
Matched Name: … (3Z)-1-[(6-fluoro-4H-1,3-benzodioxin-8-yl)methyl]-4-phenyl-1H-indole-2,3-dione 3-oxime …
Matched Iupac: … (3Z)-1-[(6-fluoro-2,4-dihydro-1,3-benzodioxin-8-yl)methyl]-3-(hydroxyimino)-4-phenyl-2,3-dihydro-1H-indol …
Matched Iupac: … (3Z)-1-[(6-fluoro-2,4-dihydro-1,3-benzodioxin-8-yl)methyl]-3-(hydroxyimino)-4-phenyl-2,3-dihydro-1H-indol …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure ... 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-one ... 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Description: … Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum …
Recilisib
Investigational
Matched Synonyms: … 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)benzoic acid ... Benzoic acid, 4-((1e)-2-(((4-chlorophenyl)methyl)sulfonyl)ethenyl)- …
Anlotinib
Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal Cancer.
Investigational
Matched Synonyms: … 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amine …
Matched Iupac: … 1-[({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl}oxy)methyl]cyclopropan-1-amine …
Matched Description: … Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal …
Matched Iupac: … 1-[({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl}oxy)methyl]cyclopropan-1-amine …
Matched Description: … Anlotinib has been investigated for the treatment of Non-small Cell Lung Cancer and Metastatic Colorectal …
JBI-802
Investigational
Matched Synonyms: … N-hydroxy-4-((4-((((1R,2S)-2-phenylcyclopropyl) amino)methyl)-1H-pyrazol-1-yl)methyl)benzamide hydrogen …
IM-156 free base
Investigational
Matched Synonyms: … 1-pyrrolidinecarboximidamide, n-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)- ... 1-Pyrrolidinecarboximidamide, N-[imino[[4-(trifluoromethoxy)phenyl]amino]methyl]- ... N-(imino((4-(trifluoromethoxy)phenyl)amino)methyl)-1-pyrrolidinecarboximidamide …
Minaprine
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin ... 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
Matched Description: … amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates ... Monoamine Oxidase Inhibitors …
Alphameprodine
Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of...
Experimental
Illicit
Matched Synonyms: … 3alpha-Ethyl-1-methyl-4-phenyl-4alpha-piperidyl propionat ... alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine ... alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidine …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … as well as itching, nausea, and respiratory depression. ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Matched Iupac: … (3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … as well as itching, nausea, and respiratory depression. ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Drostanolone propionate
Approved
Illicit
Matched Synonyms: … 2α-Methyl-4,5-dihydrotestosterone propionate ... 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate ... Testosterone, 4,5α-dihydro-2α-methyl-, propionate …
Matched Categories: … Testosterone and derivatives …
Matched Categories: … Testosterone and derivatives …
Rimantadine
An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.
Approved
Investigational
Matched Synonyms: … alpha-Methyl-1-adamantanemethylamine …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
Matched Description: … An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza …
Matched Categories: … Nucleic Acid Synthesis Inhibitors …
2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol
TIMBD is an azaresveratrol analog.
Experimental
Matched Synonyms: … 2-Methoxy-6-[[(4-methylphenyl)imino]methyl]phenol …
Matched Name: … 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol …
Matched Iupac: … 2-methoxy-6-[(1E)-[(4-methylphenyl)imino]methyl]phenol …
Matched Name: … 2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol …
Matched Iupac: … 2-methoxy-6-[(1E)-[(4-methylphenyl)imino]methyl]phenol …
6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole
Investigational
Matched Synonyms: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]-indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Matched Name: … 6-fluoro-9-methyl-9H-pyrido(3,4-B)-indole …
Matched Iupac: … 6-fluoro-9-methyl-9H-pyrido[3,4-b]indole …
Displaying drugs 876 - 900 of 2182 in total