Displaying drugs 876 - 900 of 3101 in total
Cidofovir
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid ... ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid ... [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid …
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors ... Nucleic Acid Synthesis Inhibitors …
Brivanib alaninate
Brivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Investigational
Matched Synonyms: … Brivanib alaninate …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Matched Name: … Brivanib alaninate …
Matched Description: … Brivanib alaninate has been investigated for the treatment of Colorectal Cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids …
Cangrelor
Cangrelor is an intravenous, direct-acting, reversible P2Y12 inhibitor for patients undergoing percutaneous coronary intervention (PCI) who have not been yet treated by oral P2Y12 inhibitors. An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel) is that it is an active drug not requiring metabolic conversion...
Approved
Matched Synonyms: … acid ... trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic …
Matched Iupac: … )oxy](hydroxy)phosphoryl})methyl]phosphonic acid ... methylsulfanyl)ethyl]amino}-2-[(3,3,3-trifluoropropyl)sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
Matched Iupac: … )oxy](hydroxy)phosphoryl})methyl]phosphonic acid ... methylsulfanyl)ethyl]amino}-2-[(3,3,3-trifluoropropyl)sulfanyl]-9H-purin-9-yl)oxolan-2-yl]methoxy}(hydroxy)phosphoryl …
Matched Description: … An advantage Cangrelor provides over oral P2Y12 inhibitors (such as prasugrel, ticagrelor, and clopidogrel ... ) is that it is an active drug not requiring metabolic conversion therefore providing a rapid onset and …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Blood and Blood Forming Organs …
Daprodustat
Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …
Matched Description: … HIF1α and HIF2α and the induces erythropoiesis. ... As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular ... non-inferior to erythropoiesis-stimulating agents regarding the change in the hemoglobin level from baseline and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Hypoxia-Inducible Factor-Proline Dioxygenases, antagonists & inhibitors …
Caspofungin
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Synonyms: … hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts name: … Caspofungin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Caspofungin Acetate ... Caspofungin acetate ... Caspofungin Acetate for Injection …
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts name: … Caspofungin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Caspofungin Acetate ... Caspofungin acetate ... Caspofungin Acetate for Injection …
Difluprednate
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Synonyms: … Difluoroprednisolone butyrate acetate …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated ... It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. ... Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
[2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine
Experimental
Matched Name: … [2,4,6-Triisopropyl-Phenylsulfonyl-L-[3-Amidino-Phenylalanine]]-Piperazine-N'-Beta-Alanine …
Levacetylmethadol
Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. It is used mainly in the treatment of narcotic dependence.
Levacetylmethadol was withdrawn from use in the European Union due to its high risk of QT interval prolongation. The production of levacetylmethadol in the US has ceased...
Approved
Investigational
Withdrawn
Matched Synonyms: … Levomethadyl acetate ... Levo-methadyl acetate ... (1S,4S)-4-(dimethylamino)-1-ethyl-2,2-diphenylpentyl acetate …
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Levacetylmethadol hydrochloride …
Matched Iupac: … (3S,6S)-6-(dimethylamino)-4,4-diphenylheptan-3-yl acetate …
Matched Description: … Levacetylmethadol is a narcotic analgesic with a long onset and duration of action. …
Matched Salts name: … Levacetylmethadol hydrochloride …
N-(carboxycarbonyl)-D-phenylalanine
N-(carboxycarbonyl)-D-phenylalanine is a solid. This compound belongs to the n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. It targets the protein hypoxia-inducible factor 1-alpha inhibitor.
Experimental
Matched Name: … N-(carboxycarbonyl)-D-phenylalanine …
Matched Iupac: … (2R)-2-(carboxyformamido)-3-phenylpropanoic acid …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. ... This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen …
Matched Iupac: … (2R)-2-(carboxyformamido)-3-phenylpropanoic acid …
Matched Description: … N-(carboxycarbonyl)-D-phenylalanine is a solid. ... This compound belongs to the n-acyl-alpha amino acids. ... These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen …
4-Hydroxy-L-Threonine-5-Monophosphate
Experimental
Matched Name: … 4-Hydroxy-L-Threonine-5-Monophosphate …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
Matched Iupac: … (2S,3S)-2-amino-3-hydroxy-4-(phosphonooxy)butanoic acid …
N(6)-(pyridoxal phosphate)-L-lysine
Experimental
Matched Synonyms: … N6-((3-Hydroxy-2-methyl-5-((phosphonooxy)methyl)-4-pyridinyl)methylene)-L-lysine ... (S)-2-amino-6-[(3-hydroxy-2-methyl-5-phosphonooxymethyl-4-pyridine)methyleneamino]hexanoic acid …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Matched Name: … N(6)-(pyridoxal phosphate)-L-lysine …
Matched Iupac: … 2-amino-6-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]hexanoic acid …
Glutamic acid
A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Synonyms: … Glutamic acid ... L-Glutamic acid ... (S)-Glutamic acid …
Matched Name: … Glutamic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid Hydrochloride Nu Life ... Aminosyn II and Dextrose …
Matched Salts name: … Glutamic acid hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... glutamic acid hydrochloride ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids …
Matched Products: … Glutamic Acid HCl Cap 325mg …
Matched Name: … Glutamic acid …
Matched Iupac: … (2S)-2-aminopentanedioic acid …
Matched Description: … A peptide that is a homopolymer of glutamic acid. …
Matched Mixtures name: … Glutamic Acid Pepsin and Betaine Tablets ... Glutamic Acid Hydrochloride Nu Life ... Aminosyn II and Dextrose …
Matched Salts name: … Glutamic acid hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... glutamic acid hydrochloride ... Alimentary Tract and Metabolism ... Amino Acids, Acidic ... Amino Acids …
Matched Products: … Glutamic Acid HCl Cap 325mg …
DADLE
A delta-selective opioid (ANALGESICS, OPIOID). It can cause transient depression of mean arterial blood pressure and heart rate.
Experimental
Matched Synonyms: … L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-D-leucine …
Matched Iupac: … -amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Leucine …
Matched Iupac: … -amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamido]-4-methylpentanoic acid …
Matched Description: … It can cause transient depression of mean arterial blood pressure and heart rate. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enkephalin, Leucine …
Mavodelpar
Investigational
Matched Synonyms: … REN-001 free acid ... (4-{(E)-3-(4-fluorophenyl)-3-[4-(3-morpholin-4-yl-prop-1ynyl)phenyl]allyloxy}-2-methylphenoxy)acetate …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Matched Iupac: … fluorophenyl)-3-{4-[3-(morpholin-4-yl)prop-1-yn-1-yl]phenyl}prop-2-en-1-yl]oxy}-2-methylphenoxy)acetic acid …
Acetic acid
Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Synonyms: … Acetic acid ... Ethoic acid ... acide acétique …
Matched Name: … Acetic acid …
Matched Iupac: … acetic acid …
Matched Description: … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. ... It is used locally, occasionally internally, as a counterirritant and also as a reagent. ... (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Acetates ... Indicators and Reagents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Acids, Acyclic …
Matched Products: … Acetic Acid …
Matched Name: … Acetic acid …
Matched Iupac: … acetic acid …
Matched Description: … Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. ... It is used locally, occasionally internally, as a counterirritant and also as a reagent. ... (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria …
Matched Mixtures name: … Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Acetates ... Indicators and Reagents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Acids, Acyclic …
Matched Products: … Acetic Acid …
N-[O-Phosphono-Pyridoxyl]-Isoleucine
Experimental
Matched Name: … N-[O-Phosphono-Pyridoxyl]-Isoleucine …
Matched Iupac: … 2R,3S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-3-methylpentanoic acid …
Matched Iupac: … 2R,3S)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]-3-methylpentanoic acid …
N-Pyridoxyl-Glycine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Glycine-5-Monophosphate …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acid …
Matched Iupac: … 2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]acetic acid …
Cystein-S-Yl Cacodylate
Experimental
Matched Name: … Cystein-S-Yl Cacodylate …
Matched Iupac: … (2R)-2-amino-3-[(dimethylarsoryl)sulfanyl]propanoic acid …
Matched Iupac: … (2R)-2-amino-3-[(dimethylarsoryl)sulfanyl]propanoic acid …
N-Pyridoxyl-Threonine-5-Monophosphate
Experimental
Matched Name: … N-Pyridoxyl-Threonine-5-Monophosphate …
Matched Iupac: … 3-hydroxy-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]butanoic acid …
Matched Iupac: … 3-hydroxy-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]butanoic acid …
PARA-NITROBENZYL GLUTARYL GLYCINIC ACID
Experimental
Matched Name: … PARA-NITROBENZYL GLUTARYL GLYCINIC ACID …
Matched Iupac: … 2-(4-{[(4-nitrophenyl)methyl]carbamoyl}butanamido)acetic acid …
Matched Iupac: … 2-(4-{[(4-nitrophenyl)methyl]carbamoyl}butanamido)acetic acid …
AP-102
Investigational
Matched Synonyms: … L-threoninamide, 4-amino-3-iodo-d-phenylalanyl-l-cysteinyl-3-iodo-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl-l-cysteinyl …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Dimercaptosuccinic acid
Approved
Experimental
Matched Synonyms: … 2,3-Dimercaptosuccinic acid ... 2,3-Dimercaptobutanedioic acid …
Matched Name: … Dimercaptosuccinic acid …
Matched Iupac: … 2,3-disulfanylbutanedioic acid …
Matched Salts name: … Sodium dimercaptosuccinic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … Dimercaptosuccinic Acid DMSA …
Matched Name: … Dimercaptosuccinic acid …
Matched Iupac: … 2,3-disulfanylbutanedioic acid …
Matched Salts name: … Sodium dimercaptosuccinic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... Dicarboxylic Acids …
Matched Products: … Dimercaptosuccinic Acid DMSA …
5'-O-(L-Cysteinylsulfamoyl)adenosine
Experimental
Matched Synonyms: … 5'-O-(N-(L-Cysteinyl)-sulfamoyl)adenosine …
Displaying drugs 876 - 900 of 3101 in total