Displaying drugs 9051 - 9075 of 12121 in total
9CUAB30
9 Cuab30 has been used in trials studying the treatment and prevention of HER2/Neu Positive, HER2/Neu Negative, No Evidence of Disease, Estrogen Receptor Negative, and estrogen receptor positive, among others.
Investigational
Matched Iupac: … (2E,4E,6Z)-3,7-dimethyl-8-[(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidene]octa-2,4,6-trienoic acid …
5-Mercaptoethanol-2-decenoyl-coenzyme A
Experimental
Matched Name: … 5-Mercaptoethanol-2-decenoyl-coenzyme A …
Matched Iupac: … 6-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-({[hydroxy({hydroxy[(4R)-4-hydroxy-2,2-dimethyl-3-oxo-4-({2-[(2- ... oxy)phosphoryl]oxy}methyl)-4-(phosphonooxy)oxolan-2-yl]-7H-9lambda5-purin-9-ylium ... {[(2E,5S)-5-[(2-oxoethyl)sulfanyl]dec-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}amino)butoxy]phosphoryl} …
Matched Iupac: … 6-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-({[hydroxy({hydroxy[(4R)-4-hydroxy-2,2-dimethyl-3-oxo-4-({2-[(2- ... oxy)phosphoryl]oxy}methyl)-4-(phosphonooxy)oxolan-2-yl]-7H-9lambda5-purin-9-ylium ... {[(2E,5S)-5-[(2-oxoethyl)sulfanyl]dec-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}amino)butoxy]phosphoryl} …
Inhibitor Idd 384
Experimental
Matched Iupac: … 2-{2,6-dimethyl-4-[2-(2-methylphenyl)acetamido]benzenesulfonamido}acetic acid …
Phosphate ion P-32
Experimental
Dilpacimab
Dilpacimab is under investigation in clinical trial NCT03368859 (A Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and Bevacizumab).
Investigational
Elvucitabine
Investigational
Matched Iupac: … 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-1,2-dihydropyrimidin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
9r,13r-Opda
Experimental
Matched Iupac: … 8-[(1R,5R)-4-oxo-5-(pent-2-en-1-yl)cyclopent-2-en-1-yl]octanoic acid …
ATL1101
ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis. ATL1101 is being developed as a cream for the topical treatment of mild to moderate cases of psoriasis.
Investigational
Matched Description: … ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, …
SSR-126517E
SSR-126517E is a second generation synthetic pentasaccharide that binds antithrombin with such high affinity that it assumes a plasma half-life of 80 hours.
Investigational
Indium In-111
Indium In-111 is under investigation in clinical trial NCT00493454 (Ibritumomab Tiuxetan for Treatment of Non-Follicular CD20+ Indolent Lymphomas).
Investigational
Endothelin-1
Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin).
Investigational
Matched Synonyms: … Endothelin 1 (pig) ... Endothelin 1 (rat) ... Endothelin 1 (human) …
Matched Name: … Endothelin-1 …
Matched Description: … Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation …
Matched Categories: … Endothelin-1, antagonists & inhibitors …
Matched Name: … Endothelin-1 …
Matched Description: … Endothelin 1 is under investigation in clinical trial NCT00745693 (The Effects of Diesel Exhaust Inhalation …
Matched Categories: … Endothelin-1, antagonists & inhibitors …
Fluorine F-18
Fluorine-18 is under investigation in clinical trial NCT00870974 (A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions).
Investigational
Reversin 121
Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance.
Experimental
Matched Iupac: … tert-butyl (2S)-2-[(2S)-4-(benzyloxy)-2-{[(tert-butoxy)carbonyl]amino}-4-oxobutanamido]-6-{[(benzyloxy …
Gold cation (1+)
Experimental
Matched Synonyms: … Gold(1+) ... Gold ion(1+) ... Gold(1+) ion …
Matched Name: … Gold cation (1+) …
Matched Iupac: … gold(1+) ion …
Matched Name: … Gold cation (1+) …
Matched Iupac: … gold(1+) ion …
GX-19 Vaccine
The GX-19 vaccine is a DNA vaccine created by Genexine, Inc. Company in Gyeonggi, Korea . As of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Investigational
Matched Synonyms: … DNA vaccine expressing SARS-CoV-2 S-protein antigen …
SMART101
SMART101 is an investigational cell therapy comprising human allogeneic CD34-CD7+ T cell progenitors that were cultured ex vivo.
Investigational
ATL1102
ATL1102 is a second-generation antisense inhibitor of CD49d, an immunesystem protein known as VLA-4, an immune cell molecule. It works by entering cells and targeting genes.
Investigational
Matched Description: … ATL1102 is a second-generation antisense inhibitor of CD49d, an immunesystem protein known as VLA-4, …
GMX1777
GMX1777 is a water-soluble prodrug of the cyanoguanidine compound GMX1778 with potential antineoplastic activity. In vivo, apoptosis inducer GMX1777 is rapidly converted into GMX1778 through hydrolytic cleavage of a carbonate ester bond. Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa...
Investigational
Bryostatin 1
Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.
Investigational
Matched Synonyms: … Bryostatin-1 …
Matched Name: … Bryostatin 1 …
Matched Iupac: … ]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1 ... ^{3,7}.1^{11,15}]nonacos-8-en-12-yl (2E,4E)-octa-2,4-dienoate ... (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl …
Matched Description: … Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. …
Matched Name: … Bryostatin 1 …
Matched Iupac: … ]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.1 ... ^{3,7}.1^{11,15}]nonacos-8-en-12-yl (2E,4E)-octa-2,4-dienoate ... (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl …
Matched Description: … Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease. …
JHU-75528 C-11
JHU-75528 C-11 is under investigation in clinical trial NCT03204305 (Brain Imaging of Cannabinoid Receptors).
Investigational
Matched Iupac: … 4-cyano-1-(2,4-dichlorophenyl)-5-[4-(11C)methoxyphenyl]-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide …
HQP1351
HQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).
Investigational
Matched Iupac: … 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-(2-{1H-pyrazolo[3,4-b]pyridin …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
CAR BCMA-CS1
CAR BCMA-CS1 is a lentiviral transfected chimeric antigen receptor (CAR) T-cell therapy modified to target B-cell maturation antigen and CS1.
Investigational
ANG1005
Investigational
CT103A
CT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.
Investigational
Displaying drugs 9051 - 9075 of 12121 in total