Displaying drugs 9101 - 9125 of 9930 in total
Lapaquistat
Lapaquistat is under investigation in clinical trial NCT00256178 (Efficacy of Lapaquistat Acetate and Simvastatin in Subjects With Primary Dyslipidemia.).
Investigational
Matched Iupac: … 2-(1-{2-[(3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Zotatifin
Zotatifin is under investigation in clinical trial NCT04092673 (Study of Eft226 in Subjects With Selected Advanced Solid Tumor Malignancies).
Investigational
Matched Iupac: … [6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-6-yl]benzonitrile ... 4-[(2S,3R,4S,5S,6R)-4-[(dimethylamino)methyl]-2,3-dihydroxy-10,12-dimethoxy-5-phenyl-7-oxa-11-azatricyclo …
Ociperlimab
Ociperlimab is under investigation in clinical trial NCT04866017 (A Study to Compare Ociperlimab Plus Tislelizumab Versus Durvalumab Following Concurrent Chemoradiotherapy (Ccrt) in Patients With Stage III Unresectable Non-small Cell Lung Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human receptor tigit) (human-mus musculus monoclonal bgb-a1217 .gamma.1-chain …
Diminazene
Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide, diminazine aceturate, or Diminazene aceturate, is a trypanocidal agent. Major brands of Diminazene are Berenil, Pirocide, Ganasag, and Azidin. This substance is a solid. This compound belongs to the phenylhydrazines. These are compounds containing a phenylhydrazide moiety, which consists of a hydrazide substituent...
Experimental
Matched Synonyms: … 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide …
Matched Iupac: … 4-[(2E)-3-(4-carbamimidoylphenyl)triaz-2-en-1-yl]benzene-1-carboximidamide …
Matched Description: … Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide ... Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive …
Matched Iupac: … 4-[(2E)-3-(4-carbamimidoylphenyl)triaz-2-en-1-yl]benzene-1-carboximidamide …
Matched Description: … Diminazene, also known as Diminazine, 4,4'-(Diazoamino)benzamidine, 4,4'-(1-triazene-1,3-diyl)bis-benzenecarboximidamide ... Known drug targets of diminazene include HTH-type transcriptional regulator QacR, trypsin-1, amiloride-sensitive …
rPSGL-Ig
Recombinant P-selectin glycoprotein ligand IgG fusion protein (rPSGL-Ig) is a fusion protein of human P-selectin ligand and IgG1-Fc.
Investigational
Matched Synonyms: … rPSGL-1-Ig ... Recombinant soluble PSGL-1 Fc chimera …
Timolumab
Timolumab is a recombinant, fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 (VAP-1).
Investigational
Matched Synonyms: … (VAP-1) ... fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 …
Matched Description: … (VAP-1). ... fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 …
Matched Description: … (VAP-1). ... fully-human, IgG4 immunoglobulin with antigen-binding specificity for human vascular adhesion protein-1 …
Tividenofusp alfa
Tividenofusp alfa, also known as DNL-310, is a brain-penetrant enzyme replacement therapy being investigated for the treatment of Hunter syndrome.
Investigational
Matched Synonyms: … DNL-310, recombinant iduronate 2-sulfatase …
6-hydroxydopa quinone
Experimental
Matched Synonyms: … (S)-α-amino-4-hydroxy-3,6-dioxo-1,4-cyclohexadiene-1-propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
Matched Iupac: … (2S)-2-amino-3-(4-hydroxy-3,6-dioxocyclohexa-1,4-dien-1-yl)propanoic acid …
GTB-3550
GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form of Interleukin 15 (IL-15).
Investigational
Netakimab
Netakimab is under investigation in clinical trial NCT03447704 (International Multicenter Comparative Randomized Placebo-controlled Clinical Study of Efficacy and Safety of BCD-085 in Patients With Ankylosing Spondylitis).
Investigational
Ananain
Investigational
Giloralimab
Giloralimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination With IV Modified FOLFIRINOX (Mffx) With or Without IV Budigalimab Compared to Mffx in Adult Participants With Untreated Pancreatic Cancer Metastasis).
Investigational
Matched Synonyms: … Immunoglobulin g1, anti-(human cd40 antigen) (human-mus musculus monoclonal pr-1614645 .gamma.1-chain …
Malachite Green
Experimental
Matched Synonyms: … malachite green(1+) …
Matched Iupac: … 4-{[4-(dimethylamino)phenyl](phenyl)methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium …
Matched Iupac: … 4-{[4-(dimethylamino)phenyl](phenyl)methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium …
6-Hydro-1-Methyladenosine-5'-Monophosphate
Experimental
Matched Name: … 6-Hydro-1-Methyladenosine-5'-Monophosphate …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
Matched Iupac: … {[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-imino-1-methyl-6,9-dihydro-1H-purin-9-yl)oxolan-2-yl]methoxy}phosphonic …
1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE
Experimental
Matched Name: … 1-(HYDROXYMETHYLENEAMINO)-8-HYDROXY-OCTANE …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Matched Iupac: … 8-[(hydroxymethyl)amino]octan-1-ol …
Botaretigene sparoparvovec
Investigational
Matched Synonyms: … HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUS ADENO-ASSOCIATED VIRUS 2 …
Rostaporfin
Investigational
Matched Iupac: … {10,13}.1^{15,18}.0^{2,6}]hexacosa-1(23),2(6),3,8,10(25),11,13,15,17,19,21-undecaene-7,24-diide chloride ... ethoxycarbonyl)-5,11,16,21-tetraethyl-12,17,22,26-tetramethyl-7,23,24,25-tetraazahexacyclo[18.2.1.1^{5,8}.1^ …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Poloxalene
Ethylene oxide/propylene oxide copolymer is used as a food additive. It belongs to the family of Epoxides. These are compounds containing a cyclic ether with three ring atoms (one oxygen and two carbon atoms).
Investigational
Vet approved
Matched Iupac: … 2-methyloxirane; oxirane …
CVnCoV
The CVnCov Vaccine (or CV07050101) is in development by CureVac AG. The vaccine uses mRNA technology to create a protein associated with SARS-CoV2, and upon administration and replication, to initiate subsequent immune responses in the body. As of June 2020, the company received regulatory approval from German and Belgian Authorities...
Investigational
Matched Synonyms: … SARS-CoV-2 mRNA vaccine …
Matched Description: … 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 …
Matched Description: … 2020, the company received regulatory approval from German and Belgian Authorities to commence Phase 1 …
N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide
N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide is a solid. This compound belongs to the diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5.
Experimental
PRGN-3006
PRGN-3006 are autologous CD3+ T cells genetically modified using a non-viral system to express a CD33 CAR, membrane-bound interleukin-15, and a truncated form of human HER1T (kill switch) on the cell surface.
Investigational
Flumecinol
Investigational
Matched Synonyms: … 1-(3-trifluoromethylphenyl)-1-phenylpropan-1-ol …
Matched Iupac: … 1-phenyl-1-[3-(trifluoromethyl)phenyl]propan-1-ol …
Matched Iupac: … 1-phenyl-1-[3-(trifluoromethyl)phenyl]propan-1-ol …
FK-960
Investigational
Matched Synonyms: … N-(4-Acetyl-1-piperazinyl)-4-fluorobenzamide …
Matched Iupac: … N-(4-acetylpiperazin-1-yl)-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-(4-acetylpiperazin-1-yl)-4-fluorobenzamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Thiamine disulfide
Experimental
Matched Iupac: … ]formamido}-5-hydroxypent-2-en-3-yl]disulfanyl}-5-hydroxypent-2-en-2-yl]formamide ... N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(2Z)-3-{[(2Z)-2-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Lithium cation
Lithium was used during the 19th century to treat gout. Lithium salts such as lithium carbonate (Li2CO3), lithium citrate, and lithium orotate are mood stabilizers. They are used in the treatment of bipolar disorder, since unlike most other mood altering drugs, they counteract both mania and depression. Lithium can also...
Experimental
Matched Iupac: … lithium(1+) ion …
Matched Description: … is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, …
Matched Description: … is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, …
Displaying drugs 9101 - 9125 of 9930 in total