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Displaying drugs 901 - 925 of 992 in total

3-{[4-([amino(imino)methyl]aminosulfonyl)anilino]methylene}-2-oxo-2,3-dihydro-1H-indole

Experimental
Matched Name: … 3-{[4-([amino(imino)methyl]aminosulfonyl)anilino]methylene}-2-oxo-2,3-dihydro-1H-indole …

Midazolam

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and ... This drug is unique from others in this class due to its rapid onset of effects and short duration of …
Matched Salts name: … Midazolam hydrochloride …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Hypnotics and Sedatives ... Benzodiazepines and benzodiazepine derivatives …
Matched Products: … Midazolam Hydrochloride ... Midazolam hydrochloride ... MIDAZOLAM HYDROCHLORIDE …

Ziprasidone

Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior. These mental illnesses can often be accompanied by comorbidities such as depression and substance abuse, and can significantly impact the quality of life of patients and caregivers. Luckily, several treatment options for psychotic disorders have been...
Approved
Matched Description: … Disorders such as schizophrenia and bipolar disorder can significantly impair mood, cognition, and behavior ... abuse, and can significantly impact the quality of life of patients and caregivers. ... [A180748] It can effectively reduce the rate and time of relapses in schizophrenia, and can be used to …
Matched Salts name: … Ziprasidone hydrochloride …
Matched Products: … Ziprasidone Hydrochloride ... Ziprasidone hydrochloride …

Quercetin

Quercetin is a flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin.
Experimental
Investigational
Matched Synonyms: … poly (lactide-co-glycolide)-polyethylene glycol nanoparticles encapsulating quercetin …
Matched Description: … Glycosylated forms include RUTIN and quercetrin. …

Lymecycline

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … Tetracycline-L-methylene lysine …
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and ... has been proven a cost-effective alternative to treatment with [minocycline] with comparable safety and ... It is marketed by Galderma and used in the UK as well as New Zealand in addition to other countries. …

Aztreonam

A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … (Z,)-2-((((2-Amino-4-thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino …
Matched Iupac: … azaniumyl-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-methyl-4-oxoazetidine-1-sulfonate …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges ... A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. …
Matched Categories: … Lactams ... beta-Lactams …

N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide

Experimental
Matched Name: … N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide …
Matched Iupac: … N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide …

4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

Experimental
Matched Name: … 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 4-chloro-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …

3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

Experimental
Matched Name: … 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 3-bromo-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … and cephalosporins. ... it remains a valuable option in the face of growing resistance to front-line antibiotics such as β-lactams ... concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Salts name: … Tobramycin sulfate ... Tobramycin hydrochloride …
Matched Products: … Tobramycin Sulfate …

Indinavir

A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Synonyms: … Indinavir anhydrous …
Matched Description: … A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. …
Matched Salts name: … Indinavir sulfate ... Indinavir sulfate ethanolate …

Exisulind

Investigational
Matched Synonyms: … Sulindac sulfone …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfonylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …

p-Toluenesulfonic acid

Experimental
Matched Synonyms: … para-toluene sulfonate …

Bosentan

Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … bosentan anhydrous …
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

AVR-RD-05

AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase …
Matched Description: … autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase …

9-Amino-2-deoxy-2,3-dehydro-n-acetyl-neuraminic acid

Experimental
Matched Synonyms: … (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic …

Fluoxetine

Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Description: … [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine ... Olanzapine and Fluoxetine …
Matched Salts name: … Fluoxetine hydrochloride …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … ANDEP ... Fluoxetine Hydrochloride ... Fluoxetine hydrochloride …

Piperacillin

Semisynthetic, broad-spectrum, ampicillin derived ureidopenicillin antibiotic proposed for pseudomonas infections. It is also used in combination with other antibiotics.
Approved
Matched Synonyms: … Piperacillin anhydrous …
Matched Mixtures name: … Piperacillin and Tazobactam ... Piperacillin and Tazobactam ... Piperacillin and Tazobactam …
Matched Categories: … Lactams ... beta-Lactams ... Beta-Lactam Antibacterials ... Anti-Pseudomonal Beta-Lactams …

Buprenorphine

Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … who require larger and more frequent doses. ... Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist ... an improved safety profile with a lower risk of overdose and respiratory depression. …
Matched Mixtures name: … Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Buprenorphine hydrochloride …
Matched Products: … Buprenorphine Hydrochloride ... Buprenorphine hydrochloride ... Buprenorphine Hydrochloride Sublingual …

2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate

Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate …
Matched Iupac: … 2-(cycloheptylmethyl)-1,1-dioxo-1lambda6-benzothiophen-6-yl sulfamate …

4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide

Experimental
Matched Name: … 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …
Matched Iupac: … 4-tert-butyl-N'-[(E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide …

Nebivolol

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure ... [A182579] Nebivolol and other beta blockers are generally not first line therapies as many patients are …
Matched Salts name: … Nebivolol hydrochloride …
Matched Categories: … valsartan and nebivolol ... nebivolol and thiazides ... nebivolol and amlodipine ... zofenopril and nebivolol ... Beta Blocking Agents and Thiazides …
Matched Products: … NEBIVOLOL HYDROCHLORIDE ... Nebivolol Hydrochloride …

Eprosartan

Eprosartan is an angiotensin II receptor antagonist used to treat hypertension. It performs 2 actions on the renin angiotensin system. By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs. By inhibiting norepinephrine production, blood pressure is further reduced.
Approved
Matched Synonyms: … (E)-α{[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazole-5-yl]methylene}-2-thiopheneproprionic acid …
Matched Description: … By preventing the binding of angiotensin II to AT1, vascular smooth muscle relaxes and vasodilation occurs …
Matched Categories: … eprosartan and diuretics ... Angiotensin II receptor blockers (ARBs) and diuretics …

Fingolimod

Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … neurological, physical, and cognitive effects. ... It was developed by Novartis and initially approved by the FDA in 2010. ... Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe …
Matched Salts name: … Fingolimod hydrochloride ... Fingolimod lauryl sulfate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Fingolimod Hydrochloride …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … LEVOPHED SULFITE FREE CONCENTRATE SOLUTION FOR IV INFUSION 1MG/ML …
Displaying drugs 901 - 925 of 992 in total