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Displaying drugs 901 - 925 of 3051 in total
Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile. As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile...
Experimental
Matched Synonyms: … Taurochenodeoxycholic acid
Matched Name: … Taurochenodeoxycholic acid
Matched Iupac: … dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]ethane-1-sulfonic acid
Matched Description: … As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely ... It is also being investigated for its role in inflammation and cancer therapy. ... used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics ... Cholic Acids ... Alkanesulfonic Acids ... Sulfur Acids
Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Synonyms: … Tauroursodesoxycholic acid
Matched Name: … Tauroursodeoxycholic acid
Matched Iupac: … -dihydroxy-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid
Matched Description: … [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as ... and safety,[A249070] but a much higher hydrophilicity. …
Matched Salts name: … Tauroursodeoxycholic acid dihydrate …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Bile Acids and Salts ... Bile acids and derivatives ... Cholic Acids ... Taurodeoxycholic Acid
Spaglumic acid is the β-aspartyl isoform of N-Acetyl-l-aspartylglutamate (isospaglumic Acid is N-(N-Acetyl-l-α-aspartyl)-l-glutamic acid). In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. Spaglumic acid is a mast cell stabilizer. Thus it is used in allergic conditions such as allergic conjunctivitis. Specifically spaglumic acid is approved...
Experimental
Matched Synonyms: … Spaglumic acid ... N-Acetyl-L-β-aspartyl-L-glutamic acid
Matched Name: … Spaglumic acid
Matched Iupac: … (2S)-2-[(3S)-3-carboxy-3-acetamidopropanamido]pentanedioic acid
Matched Description: … Specifically spaglumic acid is approved in Portugal under the brand name Naabak and in Greece under the ... In eye drops, spaglumic acid is either a magnesium or sodium salt of N-Acetyl-l-aspartylglutamate. ... )-l-glutamic acid). …
Matched Categories: … Decongestants and Antiallergics ... spaglumic acid ... spaglumic acid
Uric acid is the last product of purine metabolism in humans. The formation of uric acid is through the enzyme xanthine oxidase, which oxidizes oxypurines. Normally a small amount of uric acid is present in the body, but when there is an excess amount in the blood, called hyperuricemia, this...
Investigational
Matched Synonyms: … Lithic acid ... Uricum acidum
Matched Name: … Uric acid
Matched Description: … As a therapeutic agent, it is known that uric acid is increased in response to oxidative stress, and ... blood, called hyperuricemia, this can lead to gout and formation of kidney stones. ... Uric acid is the last product of purine metabolism in humans. …
Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Synonyms: … Gadoteric acid
Matched Name: … Gadoteric acid
Matched Description: … acid) used for its chelating properties, and gadolinium (Gd3+). ... Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based ... [A263131] It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic …
Matched Categories: … gadoteric acid
Picosulfuric acid is found in laxative products. Sodium picosulfate is a used to treat constipation or induce colon cleansing to prepare the large bowels before colonoscopy or surgery. The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian market in 2005 and has been used in...
Approved
Matched Name: … Picosulfuric acid
Matched Iupac: … {4-[(pyridin-2-yl)[4-(sulfooxy)phenyl]methyl]phenyl}oxidanesulfonic acid
Matched Description: … The combination product containing sodium picosulfate and magnesium citrate was introduced to the Canadian ... Picosulfuric acid is found in laxative products. ... market in 2005 and has been used in European countries for many years. …
Matched Mixtures name: … Sodium Picosulfate, Magnesium Oxide and Anhydrous Citric Acid
Matched Salts name: … Sodium picosulfate monohydrate ... Sodium picosulphate anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Acyclic ... Carboxylic Acids ... Tricarboxylic Acids ... sodium picosulfate …
Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Name: … Iopodic acid
Matched Iupac: … 3-(3-{[(dimethylamino)methylidene]amino}-2,4,6-triiodophenyl)propanoic acid
Matched Description: … a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. ... Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by ... It was developed and filed to the FDA by the company BRACCO. …
Matched Salts name: … Ipodate sodium
Matched Categories: … sodium iopodate …
Matched Products: … Oragrafin Sodium 0.5gm …
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … Levomefolic acid ... (6S)-5-Methyltetrahydrofolic acid ... 5-methyl-(6S)-tetrahydrofolic acid
Matched Name: … Levomefolic acid
Matched Iupac: … -amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido}pentanedioic acid
Matched Description: … Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form ... Supplementation of levomefolic acid is desired over folic acid due to reduced potential for masking vitamin ... regulation of homocysteine, where it methylates homocysteine and forms methionine and tetrahydrofolate …
Matched Mixtures name: … Levomefolate Calcium, Cyanocobalamin and Pyridoxine Hydrochloride ... Sodium polysulthionate, 5-methyltetrahydrofolate ... Levomefolate Calcium Acetylcysteine and Mecobalamin Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Folic Acid and Derivatives ... Enzymes and Coenzymes ... Amino Acids, Acidic ... Amino Acids
Chlorogenic Acid has been used in trials studying the treatment of Advanced Cancer and Impaired Glucose Tolerance.
Investigational
Matched Name: … Chlorogenic Acid
Matched Iupac: … 3R,4R,5R)-3-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic acid
Matched Description: … Chlorogenic Acid has been used in trials studying the treatment of Advanced Cancer and Impaired Glucose …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids
Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Approved
Investigational
Matched Synonyms: … beta-betulinic acid
Matched Name: … Betulinic Acid
Matched Iupac: … 1,2,14,18,18-pentamethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0²,¹⁰.0⁵,⁹.0¹⁴,¹⁹]henicosane-5-carboxylic acid
Matched Description: … Betulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
Approved
Matched Name: … Mandelic acid
Matched Iupac: … 2-hydroxy-2-phenylacetic acid
Matched Description: … Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. ... Mandelic acid is an approved aromatic, alpha hydroxy acid [L5458]. …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions ... Acids, Carbocyclic ... Hydroxy Acids ... mandelic acid
Experimental
Matched Synonyms: … Oxolinic acid
Matched Name: … Oxolinic acid
Matched Iupac: … 5-ethyl-8-oxo-2H,5H,8H-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid
Matched Categories: … oxolinic acid
Experimental
Matched Synonyms: … Ioglycamic acid
Matched Name: … Ioglycamic acid
Matched Iupac: … 3-(2-{[(3-carboxy-2,4,6-triiodophenyl)carbamoyl]methoxy}acetamido)-2,4,6-triiodobenzoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... ioglycamic acid ... Triiodobenzoic Acids
Experimental
Matched Synonyms: … Piromidic acid
Matched Name: … Piromidic acid
Matched Iupac: … 8-ethyl-5-oxo-2-(pyrrolidin-1-yl)-5H,8H-pyrido[2,3-d]pyrimidine-6-carboxylic acid
Matched Categories: … Acids, Heterocyclic ... Nicotinic Acids ... piromidic acid
Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.
Experimental
Matched Synonyms: … Fatty acids of cod liver oil …
Matched Name: … Morrhuic acid
Matched Description: … Morrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil. …
Matched Salts name: … Morrhuate sodium
Matched Categories: … Fatty Acids
Matched Products: … Morrhuate Sodium
Experimental
Matched Synonyms: … Hydrosilicic acid ... Silicic acid hydrate …
Matched Name: … Silicic acid
Matched Categories: … Acids ... Acids, Noncarboxylic …
Experimental
Matched Synonyms: … Butedronic acid
Matched Name: … Butedronic acid
Matched Iupac: … 2-(diphosphonomethyl)butanedioic acid
Experimental
Matched Name: … Lactobionic acid
Matched Iupac: … -2,3,5,6-tetrahydroxy-4-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexanoic acid
Investigational
Matched Synonyms: … Acide abscisique …
Matched Name: … Abscisic Acid
Matched Iupac: … (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids
Experimental
Matched Synonyms: … 4'-phosphopantothenic acid ... 4'-phospho-d-pantothenic acid ... D-pantothenic acid 4'-phosphate …
Matched Name: … Phosphopantothenic acid
Matched Iupac: … 3-[(2R)-2-hydroxy-3-methyl-3-[(phosphonooxy)methyl]butanamido]propanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids
Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.[A957,L44788] Following administration, clorazepate is rapidly converted to nordiazepam (N-desmethyldiazepam), its active metabolite, before entering systemic circulation. Similar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA)...
Approved
Illicit
Matched Synonyms: … Clorazepic acid ... 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid
Matched Name: … Clorazepic acid
Matched Iupac: … 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid
Matched Description: … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant ... other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid ... depression, coma, and death. …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …
Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Approved
Withdrawn
Matched Synonyms: … Canrenoic acid
Matched Name: … Canrenoic acid
Matched Iupac: … ,15S)-14-hydroxy-2,15-dimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien-14-yl]propanoic acid
Matched Description: … Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Cidofovir is an injectable antiviral medication employed in the treatment of cytomegalovirus (CMV) retinitis in patients diagnosed with AIDS. It suppresses CMV replication through selective inhibition of viral DNA synthesis.[FDA label] It was manufactured by Gilead and initially approved by the FDA in 1996, but has since been discontinued.
Approved
Matched Synonyms: … ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid ... [(S)-2-(4-Amino-2-oxo-2H-pyrimidin-1-yl)-1-hydroxymethyl-ethoxymethyl]-phosphonic acid ... [[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
Matched Description: … [FDA label] It was manufactured by _Gilead_ and initially approved by the FDA in 1996, but has since …
Matched Categories: … Nucleic Acid Synthesis Inhibitors ... Nucleosides and Nucleotides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Synonyms: … Zinc gluconate
Matched Name: … Zinc gluconate
Matched Description: … Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc ... of common colds and with decreased symptom severity. ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration …
Matched Mixtures name: … VITAHEALTH SELENIUM VITAPLUS TABLET ... Calcium Magnesium Avec Vitamine D Et Zinc ... AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass …
Matched Salts name: … Zinc gluconate trihydrate …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Alimentary Tract and Metabolism ... zinc gluconate ... Acids, Acyclic ... Hydroxy Acids
Matched Products: … Zinc Gluconate 380mg ... Zinc Gluconate Tab 10mg ... Zinc Gluconate Tab 50mg …
Experimental
Matched Synonyms: … 2-Coumaric acid ... o-Coumaric acid ... (E)-o-hydroxycinnamic acid
Matched Name: … trans-2-hydroxycinnamic acid
Matched Iupac: … (2E)-3-(2-hydroxyphenyl)prop-2-enoic acid
Displaying drugs 901 - 925 of 3051 in total