Displaying drugs 901 - 925 of 1429 in total
Edrophonium
A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.
Approved
Matched Synonyms: … N-ethyl-3-hydroxy-N,N-dimethylanilinium ... Ethyl-(3-hydroxy-phenyl)-dimethyl-ammonium ... N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis …
Matched Iupac: … N-ethyl-3-hydroxy-N,N-dimethylanilinium …
Matched Description: … A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis …
AKV-9
Investigational
Matched Synonyms: … 1,3-Cyclohexanedione, 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]- ... 5-[(1S)-1-[3,5-Bis(trifluoromethyl)phenoxy]ethyl]-1,3-cyclohexanedione ... 5-((S)-1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)-3-hydroxycyclohex-2-en-1-one …
Matched Iupac: … 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]cyclohexane-1,3-dione …
Matched Iupac: … 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]cyclohexane-1,3-dione …
Nialamide
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 1-(2-(Benzylcarbamoyl)ethyl)-2-isonicotinoylhydrazine ... 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a
2-(1-Hexyloxyethyl)-2-devinyl pyropheophorbide-a is under investigation in clinical trial NCT01668823 (Photodynamic Therapy in Treating Patients With Lung Cancer).
Investigational
Matched Synonyms: … 3-PHORBINEPROPANOIC ACID, 14-ETHYL-9-(1-(HEXYLOXY)ETHYL)-4,8,13,18-TETRAMETHYL-20-OXO-, (3S,4S)- …
Matched Iupac: … 3-[(21S,22S)-11-ethyl-16-[1-(hexyloxy)ethyl]-12,17,21,26-tetramethyl-4-oxo-7,23,24,25-tetraazahexacyclo …
Matched Iupac: … 3-[(21S,22S)-11-ethyl-16-[1-(hexyloxy)ethyl]-12,17,21,26-tetramethyl-4-oxo-7,23,24,25-tetraazahexacyclo …
Ezogabine
Ezogabine (D23129) is a close structural analog of the centrally acting analgesic flupitrine. It is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and is currently being studied in Phase 3 trials as an adjunctive treatment for partial-onset seizures in adult patients with refractory epilepsy....
Approved
Investigational
Matched Synonyms: … Ethyl 2-amino-4-((p-fluorobenzyl)amino)carbanilate ... ethyl {2-amino-4-[(4-fluorobenzyl)amino]phenyl}carbamate ... N-(2-Amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
Matched Iupac: … ethyl N-(2-amino-4-{[(4-fluorophenyl)methyl]amino}phenyl)carbamate …
Matched Description: … is a neuronal potassium channel opener being developed as a first-in-class antiepileptic drug (AED) and …
{(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate
Experimental
Matched Name: … {(2S)-1-[N-(tert-butoxycarbonyl)glycyl]pyrrolidin-2-yl}methyl (3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
Matched Iupac: … [(2S)-1-(2-{[(tert-butoxy)carbonyl]amino}acetyl)pyrrolidin-2-yl]methyl 2-(3-chlorophenyl)acetate …
Ethchlorvynol
Ethchlorvynol is a sedative and hypnotic drug. It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.
Approved
Illicit
Withdrawn
Matched Synonyms: … 1-chloro-3-ethyl-1-penten-4-yn-3-ol ... 1-Chloro-3-ethyl-pent-1-en-4-yn-3-ol ... ethyl β-chlorovinyl ethynyl carbinol …
Matched Description: … Ethchlorvynol is a sedative and hypnotic drug. ... It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance …
Matched Categories: … Hypnotics and Sedatives …
Matched Description: … Ethchlorvynol is a sedative and hypnotic drug. ... It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance …
Matched Categories: … Hypnotics and Sedatives …
Encainide
All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Synonyms: … (±)-2'-[2-(1-methyl-2-piperidyl)ethyl]-p-anisanilide ... 4-methoxy-2'-[2-(1-methyl-2-piperidyl)ethyl]benzanilide ... (±)-4-methoxy-N-(2-(2-(1-methyl-2-piperidinyl)ethyl)phenyl)benzamide …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Matched Description: … hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who …
Matched Iupac: … 4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide …
Matched Description: … hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who …
Bretylium
Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is used in emergency medicine, cardiology, and other specialties for the acute management of ventricular tachycardia and ventricular fibrillation. The primary mode of action for bretylium is thought to be inhibition of voltage-gated K(+) channels. Recent evidence...
Approved
Matched Synonyms: … 2-bromo-N-ethyl-N,N-dimethylbenzenemethanaminium ... N-ethyl-N,N-dimethyl-2-bromobenzenemethanaminium …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Matched Iupac: … [(2-bromophenyl)methyl](ethyl)dimethylazanium …
Matched Description: … tachycardia and ventricular fibrillation. ... Bretylium blocks the release of noradrenaline from the peripheral sympathetic nervous system, and is ... used in emergency medicine, cardiology, and other specialties for the acute management of ventricular …
Matched Mixtures name: … Bretylium Tosylate 0.4% and Dextrose 5% Inj ... Bretylium Tosylate 0.2% and Dextrose 5% Inj …
Sulpiride
Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Synonyms: … N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide ... N-((1-Ethyl-2-pyrrolidinyl)methyl)-2-methoxy-5-sulfamoylbenzamide ... 5-(Aminosulfonyl)-N-((1-ethyl-2-pyrrolidinyl)methyl)-2-methoxybenzamide …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Categories: … Benzamides and benzamide derivatives …
Moricizine
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate ... ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate ... [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Tapentadol
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596]
Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited …
Matched Description: … [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited …
Bufotenine
A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, especially in the brains, plasma, and urine of schizophrenics. Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.
Experimental
Illicit
Matched Synonyms: … 3-[2-(dimethylamino)ethyl]-5-indolol ... 3-[2-(dimethylamino)ethyl]indol-5-ol ... 3-[β-(dimethylamino)ethyl]-5-hydroxyindole …
Matched Iupac: … 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol …
Matched Description: … especially in the brains, plasma, and urine of schizophrenics. ... A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, ... Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. …
Matched Iupac: … 3-[2-(dimethylamino)ethyl]-1H-indol-5-ol …
Matched Description: … especially in the brains, plasma, and urine of schizophrenics. ... A hallucinogenic serotonin analog found in frog or toad skins, mushrooms, higher plants, and mammals, ... Bufotenin has been used as a tool in CNS studies and misused as a psychedelic. …
6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
Experimental
Matched Name: … BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE …
Alverine
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Synonyms: … N-Ethyl-3,3'-diphenyldipropylamine ... N-Ethyl-N-(3-phenylpropyl)benzenepropanamine ... N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. ... It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. …
Matched Categories: … Alimentary Tract and Metabolism …
Vinpocetine
Vinpocetine has been investigated for the treatment of Epilepsy.
Investigational
Matched Synonyms: … ETHYL APOVINCAMIN-22-OATE …
Matched Iupac: … ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Iupac: … ethyl (15S,19S)-15-ethyl-1,11-diazapentacyclo[9.6.2.0²,⁷.0⁸,¹⁸.0¹⁵,¹⁹]nonadeca-2,4,6,8(18),16-pentaene …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Elenestinib
Elenestinib is a selective KIT inhibitor.
Investigational
Matched Synonyms: … ]triazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol ... ]triazin-6-yl]-1H-pyrazol-1- yl}ethan-1-ol ... (S)-2-(4-(4-(4-(5-(1-amino-1-(4-fluorophenyl)ethyl)pyrimidin-2-yl)piperazin-1-yl)pyrrolo[2,1-f][1,2,4 …
Matched Iupac: … ]triazin-6-yl]-1H-pyrazol-1-yl}ethan-1-ol ... 2-{4-[4-(4-{5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl}piperazin-1-yl)pyrrolo[2,1-f][1,2,4 …
Matched Iupac: … ]triazin-6-yl]-1H-pyrazol-1-yl}ethan-1-ol ... 2-{4-[4-(4-{5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl}piperazin-1-yl)pyrrolo[2,1-f][1,2,4 …
Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6619, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Hydroxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide]
Experimental
Matched Name: … Al-6629, [2h-Thieno[3,2-E]-1,2-Thiazine-6-Sulfonamide,2-(3-Methoxyphenyl)-3-(4-Morpholinyl)-, 1,1-Dioxide …
(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Experimental
Matched Name: … 3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide …
Betameprodine
Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances. The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. It exerts physiological effects characteristic of opioids,...
Experimental
Illicit
Matched Synonyms: … beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin ... beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidine …
Matched Iupac: … (3R,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Matched Iupac: … (3R,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propanoate …
Matched Description: … as well as itching, nausea, and respiratory depression. ... The stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred ... It exerts physiological effects characteristic of opioids, such as analgesia, euphoria and sedation, …
Prednisolone
Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … STERILE PREDNISOLONE ACETATE SUSPENSION …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … STERILE PREDNISOLONE ACETATE SUSPENSION …
Obeticholic acid
Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury often resulting in end-stage liver failure that requires liver transplantation. Obeticholic acid is a farnesoid-X receptor (FXR) agonist used to treat this condition, possibly allowing for increased survival. In 2016, it was granted approval...
Approved
Matched Synonyms: … 6-Ethyl-CDCA ... 6alpha-Ethyl-chenodeoxycholic acid ... (3α,5β,6α,7α)-6-ethyl-3,7-dihydroxycholan-24-oic acid …
Matched Iupac: … (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and ... The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy …
Matched Iupac: … (4R)-4-[(1R,3aS,3bS,4R,5R,5aS,7R,9aS,9bS,11aR)-5-ethyl-4,7-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta …
Matched Description: … Primary biliary cirrhosis, or PBC, is a progressive and chronic condition that leads to hepatic injury ... updated its prescribing information to contraindicate the use of obeticholic acid in patients with PBC and ... The NDA from Intercept Pharmaceuticals was approved in November 2019 and obeticholic acid is expected …
Matched Categories: … Alimentary Tract and Metabolism ... Bile acids and derivatives ... Bile Acids and Salts ... Bile and Liver Therapy …
Displaying drugs 901 - 925 of 1429 in total