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Displaying drugs 901 - 925 of 1294 in total
Experimental
Matched Name: … 4-bromo-3-hydroxy-3-methyl butyl diphosphate …
Matched Iupac: … ({[(3R)-4-bromo-3-hydroxy-3-methylbutoxy](hydroxy)phosphoryl}oxy)phosphonic acid …
Cystinosis is a rare disease caused by mutations in the CTNS gene that encodes for cystinosin, a protein responsible for transporting cystine out of the cell lysosome. A defect in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and kidneys. Several preparations of cysteamine exist...
Approved
Investigational
Matched Synonyms: … beta-aminoethanethiol ... beta-Mercaptoethylamine …
Matched Description: … in cystinosin function is followed by cystine accumulation throughout the body, especially the eyes and ... preparations of cysteamine exist for the treatment of cystinosis manifestations, some in capsule form, and ... L15616] In particular, cystine deposits on the eye can cause significant discomfort throughout the day and
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids and Derivatives …
Experimental
Investigational
Matched Synonyms: … 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine ... 4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone …
N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions.[A193008,A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and phage. It has shown antiviral activity against Venezuelan equine encephalitis virus, and the human coronavirus HCoV-NL63 in vitro. N4-hydroxycytodine has been...
Experimental
Matched Synonyms: … beta-D-N-4-Hydroxycytidine ... Beta-D-N4-hydroxycytidine …
Matched Description: … in mice and human airway epithelial cells. ... A193011] N4-hydroxycytidine was first described in the literature in 1980 as a potent mutagen of bacteria and ... [A193023] It has shown antiviral activity against Venezuelan equine encephalitis virus,[A193008] and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Synonyms: … 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide ... 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide …
Matched Description: … According to 2017 American Association for the Study of Liver Diseases (AASLD) and 2015 consensus guidelines ... Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Experimental
Matched Synonyms: … L-beta-Phenyllactic acid ... alpha-hydroxy-beta-phenyl-propionic acid …
Experimental
Matched Name: … 6-(3-BROMO-2-NAPHTHYL)-1,3,5-TRIAZINE-2,4-DIAMINE …
Polaprezinc is a chelated form of zinc and L-carnosine. It is a zinc-related medicine approved for the first time in Japan, which has been clinically used to treat gastric ulcers [L1307, L1308]. It was determined that polaprezinc may be effective in pressure ulcer treatment . A study in 2013 showed...
Experimental
Matched Synonyms: … beta-Alanyl-L-histidinato zinc …
Matched Description: … Polaprezinc is a chelated form of zinc and L-carnosine. ... It was determined that polaprezinc may be effective in pressure ulcer treatment [A31856]. ... A study in 2013 showed that CO-administration of polaprezinc may be effective against small intestine …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration (FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter.
Approved
Investigational
Matched Synonyms: … beta-((p-Methanesulfonamidophenethyl)methylamino)methanesulfono-p-phenetidide …
Matched Description: … flutter, and for the chemical cardioversion to sinus rhythm from atrial fibrillation and flutter. ... Dofetilide is a class III antiarrhythmic agent that is approved by the Food and Drug Administration ( ... FDA) for the maintenance of sinus rhythm in individuals prone to the formation of atrial fibrillation and
Experimental
Matched Synonyms: … beta-galactose-6-phosphate …
Matched Name: … beta-D-galactose 6-phosphate …
Experimental
Matched Synonyms: … alpha-D-Glucopyranoside, 6-O-(1-oxooctyl)-beta-D-fructofuranosyl …
Experimental
Investigational
Matched Synonyms: … 3-methyl-beta-D-aspartic acid …
Experimental
Matched Name: … Beta-D-Glucopyranose Spirohydantoin …
Experimental
Matched Name: … 11-Deoxy-Beta-Rhodomycin …
Experimental
Matched Name: … beta-D-Galactopyranuronic acid …
Experimental
Matched Synonyms: … beta-1,4-galactotrioside …
Matched Name: … beta-(1->4)-galactotriose …
Experimental
Matched Name: … octyl beta-D-galactopyranoside …
Experimental
Matched Name: … ORTHONITROPHENYL-BETA-D-FUCOPYRANOSIDE …
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Description: … Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches ... [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available …
Matched Mixtures name: … Sumatriptan Succinate and Naproxen Sodium ... Sumatriptan and Naproxen Sodium ... Sumatriptan and Naproxen Sodium …
Matched Categories: … Genito Urinary System and Sex Hormones ... sumatriptan and naproxen ... Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … SUMATRIPTAN BETA 50MG ... SUMATRIPTAN BETA 100MG …
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... States for use in combination with tadalafil to reduce the risks of disease progression, hospitalization and
Matched Categories: … ambrisentan and tadalafil …
Matched Products: … AMBRISENTAN BETA 5 MG FTA ... AMBRISENTAN BETA 10 MG FTA …
An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Description: … in combination with estrogen, for the therapy of severe acne and hirsutism in females. ... It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, …
Matched Categories: … Antiandrogens and Estrogens ... Combination Contraceptives (with Estrogen and derivatives) ... cyproterone and estrogen ... Genito Urinary System and Sex Hormones ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Andro - Diane 10 mg - Tabletten ... CYPROTERONACETAT BETA 50MG …
Ohmefentanyl is an extremely potent opioid analgesic drug which selectively binds to the µ-opioid receptor. The Chinese have recorded ohmefentanyl as having a potency that is 6,300 times morphine. Ohmefentanyl is one of the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and etorphine which...
Illicit
Matched Synonyms: … Beta-hydroxy-3-methylfentanyl …
Matched Description: … the most potent μ -receptor agonists known, comparable to super-potent opioids such as carfentanil and ... In mice, ohmefentanyl was 28 times more powerful than fentanyl and 6300 times more effective than morphine ... Ohmefentanyl has three stereogenic centers and hence, it can derive into eight stereoisomers, currently …
Vestronidase alfa, or vestronidase alfa-vjbk, is a recombinant human lysosomal beta glucuronidase that is a purified enzyme produced by recombinant DNA technology in a Chinese hamster ovary cell line. The enzyme is a homotetramer consisted of 4 monomers with 629 amino acids, and holds the same amino acid sequence as...
Approved
Investigational
Matched Synonyms: … Recombinant human beta-glucuronidase …
Matched Description: … and patients may experience developmental delay and progressive intellectual disability [FDA Label]. ... known as Sly syndrome, which is an inherited, rare genetic metabolic condition that targets a small subset ... spleen, heart valve abnormalities, and narrowed airways which can lead to lung infections and trouble …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Lysosomal beta Glucuronidase …
Ribaxamase is under investigation in clinical trial NCT02563106 (A Study of SYN-004 for the Prevention of c.diff in Patients With a LRTI).
Investigational
Matched Synonyms: … .beta.-lactamase (synthetic bacillus licheniformis isoenzyme syn-004) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Enzymes and Coenzymes …
Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of...
Approved
Matched Description: … antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and ... The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the ... mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … EPLERENON BETA 25 MG ... EPLERENON BETA 50 MG …
Displaying drugs 901 - 925 of 1294 in total