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Displaying drugs 9326 - 9350 of 10121 in total
Vet approved
Matched Iupac: … (1S,3aS,3bS,11aS)-11a-methyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,11aH-cyclopenta[a]phenanthren-1-yl …
Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers).
Investigational
Matched Iupac: … 24),7(12),8,10,18(25),19,22-heptaen-17-one ... )-9-fluoro-15-methyl-2,11,16,20,21,24-hexaazapentacyclo[16.5.2.0^{2,6}.0^{7,12}.0^{21,25}]pentacosa-1( …
Matched Description: … Selitrectinib is under investigation in clinical trial NCT03215511 (Phase 1/2 Study of LOXO-195 in Patients …
Didesmethylrocaglamide is a naturally-occurring derivative of rocaglamide and belongs to a class of anti-cancer phytochemicals referred to as "rocaglamides" derived from plants of the genus Aglaia. While traditionally used for their insecticidal benefits, this class of compounds is now being studied for use as chemotherapeutic agents in the treatment of...
Experimental
Matched Iupac: … }]dodeca-1(12),8,10-triene-4-carboxamide ... (2S,3R,4R,5S,6R)-2,3-dihydroxy-10,12-dimethoxy-6-(4-methoxyphenyl)-5-phenyl-7-oxatricyclo[6.4.0.0^{2,6 …
INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).
Investigational
Matched Iupac: … 2H-1,4-benzoxazin-3-one ... 6-methanesulfonyl-2,2,4-trimethyl-8-{6-methyl-7-oxo-1H,6H,7H-pyrrolo[2,3-c]pyridin-4-yl}-3,4-dihydro- …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Desmoteplase is a chemical in the saliva of vampire bats. It activates plasminogen to the serine protease, plasmin. Plasmin acts by breaking down fibrin blood clots. When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting. The enzyme is called DSPA (Desmodus rotundus...
Investigational
Matched Synonyms: … rDSPA alpha 1 ... Salivary plasminogen activator alpha 1, Desmodus rotundus …
Matched Description: … Desmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1). …
Phenothiazine (PTZ) is an organic thiazine compound.
Experimental
Vet approved
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Alpha 1-antitrypsin is a glycoprotein primarily produced by hepatocytes, and to a lesser extent, immune system cells. Recombinant alpha 1-antitrypsin (rAAT) is produced from yeast, which unlike commercially available forms of plasma-derived AAT, eliminates the risk associated with blood-borne infectious agents and allows for a increased manufacturing. rAAT belongs to...
Investigational
Matched Synonyms: … Recombinant alpha 1-antitrypsin …
Matched Name: … Recombinant alpha 1-antitrypsin …
Matched Description: … Alpha 1-antitrypsin is a glycoprotein primarily produced by hepatocytes, and to a lesser extent, immune ... Recombinant alpha 1-antitrypsin (rAAT) is produced from yeast, which unlike commercially available forms …
Matched Products: … VENTIA®2% …
Fulacimstat is under investigation in clinical trial NCT02452515 (A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction).
Investigational
Matched Iupac: … 1-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro- ... 1H-inden-1-yl]-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Experimental
Matched Name: … 2-(acetylamino)-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-glucopyranose …
Matched Iupac: … yl]oxy}oxan-3-yl]acetamide ... ,5S,6R)-2,4-dihydroxy-6-(hydroxymethyl)-5-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2- …
Experimental
Matched Name: … ISOQUINOLINE-5-SULFONIC ACID (2-(2-(4-CHLOROBENZYLOXY)ETHYLAMINO)ETHYL)AMIDE …
Matched Iupac: … N-[2-({2-[(4-chlorophenyl)methoxy]ethyl}amino)ethyl]isoquinoline-5-sulfonamide …
Experimental
Matched Iupac: … 2-[(2S)-2-acetamido-3-(4-hydroxy-3,5-diiodophenyl)propanamido]acetic acid …
Bifidobacterium Longum Infantis 35624 is a probiotic being investigated for the treatment of gastrointestinal disorders, such as Crohn's disease and irritable bowel syndrome.[A259872, A259877]
Investigational
Oxibendazole is a polymerase inhibitor in phase III trials for the treatment of helminth intestinal infections.
Investigational
Vet approved
Matched Synonyms: … Methyl 5-propoxy-2-benzimidazolecarbamate ... Methyl 5-n-propoxy-2-benzimidazole carbamate ... 5-Propoxy-2-benzimidazolecarbamic acid methyl ester …
Matched Iupac: … methyl N-(6-propoxy-1H-1,3-benzodiazol-2-yl)carbamate …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Apitolisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, and Endometrial Carcinoma, among others.
Investigational
Matched Iupac: … (2S)-1-(4-{[2-(2-aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl}piperazin ... -1-yl)-2-hydroxypropan-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Phosphatidylinositol 3-Kinases, antagonists & inhibitors …
Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … N'1-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Iupac: … 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 ... (6),4,7,10,12-pentaen-9-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal uc-961 .kappa. ... Immunoglobulin g1, anti-(human receptor tyrosine kinase ror-1) (human-mus musculus monoclonal uc-961 …
Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).
Investigational
Matched Synonyms: … .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa. ... Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 …
Experimental
Matched Name: … 1-Deoxy-Ribofuranose-5'-Phosphate …
Matched Iupac: … {[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid …
Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .
Experimental
Matched Synonyms: … 2-(β-D-ribofuranosyl)-4-thiazolecarboxamide ... 2-β-D-ribofuranosyl-4-thiazolecarboxamide ... 2-Beta-D-ribofuranosyl-4-thiazolecarboxamide …
Matched Iupac: … 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide …
Experimental
Matched Name: … 1-Aminocyclopropylphosphonate …
Matched Iupac: … hydrogen (1-aminocyclopropyl)phosphonate …
Experimental
Matched Name: … 5'-deoxy-5'-piperidin-1-ylthymidine …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-[(piperidin-1-yl)methyl]oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine- …
Experimental
Matched Synonyms: … 1-methyloxy-4-sulfone-benzene …
Matched Iupac: … 4-methoxybenzene-1-sulfinate …
Experimental
Matched Synonyms: … sodium(1+) …
Matched Iupac: … sodium(1+) ion …
Displaying drugs 9326 - 9350 of 10121 in total