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Displaying drugs 9451 - 9475 of 10915 in total
Aeruginosin 98-B
Experimental
Matched Iupac: … [(2S,3aS,6R,7aS)-2-({4-[(diaminomethylidene)amino]butyl}carbamoyl)-1-[(2R,3R)-2-[(2R)-2-hydroxy-3-(4- ... hydroxyphenyl)propanamido]-3-methylpentanoyl]-octahydro-1H-indol-6-yl]oxidanesulfonic acid …
Desmeninol
Experimental
Matched Synonyms: … 2-Hydroxy-4-(methylthio) butanoic acid ... 2-Hydroxy-4-(methylthio)butanoic acid ... DL-2-hydroxy-4-(methylthio)-butyric acid …
Matched Iupac: … 2-hydroxy-4-(methylsulfanyl)butanoic acid …
Matched Salts cas: … 4857-44-7 …
Matched Iupac: … 2-hydroxy-4-(methylsulfanyl)butanoic acid …
Matched Salts cas: … 4857-44-7 …
Tapotoclax
Investigational
Matched Synonyms: … MCL-1 inhibitor AMG 176 ... MCL-1 inhibitor AMG-176 …
Matched Iupac: … (1S,3'R,6'R,7'S,8'E,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6 ... -thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo[14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16'(25' …
Matched Iupac: … (1S,3'R,6'R,7'S,8'E,11'S,12'R)-6-chloro-7'-methoxy-11',12'-dimethyl-3,4-dihydro-2H-20'-oxa-13'lambda6 ... -thia-1',14'-diazaspiro[naphthalene-1,22'-tetracyclo[14.7.2.0^{3,6}.0^{19,24}]pentacosane]-8',16'(25' …
Propentofylline
Investigational
Matched Iupac: … 3-methyl-1-(5-oxohexyl)-7-propyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bufuralol
Bufuralol is a new, non-selective -adrenoceptor blocking agent.
Experimental
Matched Iupac: … 2-(tert-butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethan-1-ol …
Lubazodone
Lubazodone (YM-992, YM-35,995) is an arylpiperazine antidepressant which was being developed as a treatment for depression and obsessive compulsive disorder, and reached phase II clinical trials, but was discontinued. It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist.
Experimental
Matched Iupac: … (2S)-2-{[(7-fluoro-2,3-dihydro-1H-inden-4-yl)oxy]methyl}morpholine …
Matched Description: … It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. …
Matched Salts cas: … 161178-10-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Description: … It acts as a serotonin reuptake inhibitor and 5-HT2A receptor antagonist. …
Matched Salts cas: … 161178-10-5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Setiptiline
Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). In Japan, the company Mochida started its commercialization for the treatment of depression started in 1989.
Experimental
Matched Iupac: … 4-methyl-4-azatetracyclo[13.4.0.0²,⁷.0⁸,¹³]nonadeca-1(19),2(7),8,10,12,15,17-heptaene …
Matched Salts cas: … 85650-57-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Salts cas: … 85650-57-3 …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Furafylline
Furafylline is a derivative of methylxanthine derivative. It was developed on the context of asthma as a long-acting alternative for theophylline.
Experimental
Matched Iupac: … 4-(5-{7-azabicyclo[2.2.1]heptan-2-yl}-2-fluoropyridin-3-yl)benzonitrile …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
D-Mannose 1-phosphate
Experimental
Matched Synonyms: … D-Mannose 1-phosphate ... Mannose 1-phosphate ... D-mannose 1-phosphates …
Matched Name: … D-Mannose 1-phosphate …
Matched Iupac: … {[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid …
Matched Name: … D-Mannose 1-phosphate …
Matched Iupac: … {[(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}phosphonic acid …
13-deoxydoxorubicin
GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.
Investigational
Matched Iupac: … (8R,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-8-(2-hydroxyethyl ... )-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione …
Henagliflozin
Henagliflozin has been used in trials studying the treatment of Type 2 Diabetes.
Investigational
Matched Iupac: … (1R,2S,3S,4R,5R)-5-{4-chloro-3-[(4-ethoxy-3-fluorophenyl)methyl]phenyl}-1-(hydroxymethyl)-6,8-dioxabicyclo …
Matched Description: … Henagliflozin has been used in trials studying the treatment of Type 2 Diabetes. …
Matched Description: … Henagliflozin has been used in trials studying the treatment of Type 2 Diabetes. …
beta-(1->4)-galactotriose
Experimental
Matched Synonyms: … β-D-Gal-(1→4)-β-D-Gal-(1→4)-β-D-Gal ... β-D-Galp-(1→4)-β-D-Galp-(1→4)-β-D-Galp ... β-D-galactosyl-(1→4)-β-D-galactosyl-(1→4)-β-D-galactose …
Matched Name: … beta-(1->4)-galactotriose …
Matched Iupac: … -2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... (2S,3R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3R,4R,5R,6R)-4,5,6-trihydroxy …
Matched Name: … beta-(1->4)-galactotriose …
Matched Iupac: … -2-(hydroxymethyl)oxan-3-yl]oxy}oxan-3-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol ... (2S,3R,4S,5R,6R)-2-{[(2R,3R,4R,5R,6S)-4,5-dihydroxy-2-(hydroxymethyl)-6-{[(2R,3R,4R,5R,6R)-4,5,6-trihydroxy …
Aspartyl-Adenosine-5'-Monophosphate
Experimental
Matched Name: … Aspartyl-Adenosine-5'-Monophosphate …
Matched Iupac: … (3S)-3-amino-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy) …
Matched Iupac: … (3S)-3-amino-4-[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy) …
3,4-Dihydroxycinnamic Acid
Experimental
Investigational
Matched Iupac: … (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid …
S-(3-Iodobenzyl)glutathione
Experimental
Matched Name: … S-(3-Iodobenzyl)glutathione …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(3-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-{[(3-iodophenyl)methyl]sulfanyl}ethyl]carbamoyl} …
3-Hydroxyimino Quinic Acid
Experimental
Matched Name: … 3-Hydroxyimino Quinic Acid …
Matched Iupac: … (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(hydroxyimino)cyclohexane-1-carboxylic acid …
Matched Iupac: … (1S,3R,4R,5E)-1,3,4-trihydroxy-5-(hydroxyimino)cyclohexane-1-carboxylic acid …
Oleylphosphocholine
Investigational
Matched Synonyms: … Ethanaminium, 2-((hydroxy((9z)-9-octadecen-1-yloxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt ... Ethanaminium, 2-((hydroxy(9-octadecenyloxy)phosphinyl)oxy)-n,n,n-trimethyl-, inner salt, (z)- …
Matched Iupac: … (9Z)-octadec-9-en-1-yl 2-(trimethylazaniumyl)ethyl phosphate …
Matched Iupac: … (9Z)-octadec-9-en-1-yl 2-(trimethylazaniumyl)ethyl phosphate …
Tyrphostin AG 835
Experimental
Matched Iupac: … (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enimidic acid …
Fenproporex
Fenproporex is an orally active stimulant drug, which was developed in the 1960s. It is used as an appetite suppressant and a treatment for obesity. It is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency....
Experimental
Illicit
Withdrawn
Matched Iupac: … 3-[(1-phenylpropan-2-yl)amino]propanenitrile …
Matched Description: … effects are less notorious than with some other agents such as diethylpropion and mazindol. [7] In ... to yield amphetamine as a metabolite. [5] However, in clinical practice, central nervous system stimulative ... Structurally, fenproporex (N-2-cyanoethylamphetamine) falls within the phenylethamine and amphetamine …
Matched Description: … effects are less notorious than with some other agents such as diethylpropion and mazindol. [7] In ... to yield amphetamine as a metabolite. [5] However, in clinical practice, central nervous system stimulative ... Structurally, fenproporex (N-2-cyanoethylamphetamine) falls within the phenylethamine and amphetamine …
Urolithin A
Urolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Fitusiran
Fitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
Investigational
3'-Deazo-Thiamin Diphosphate
Experimental
Matched Name: … 3'-Deazo-Thiamin Diphosphate …
Matched Iupac: … 3-[(4-amino-6-methylpyridin-3-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl ... )-4-methyl-1,3-thiazol-3-ium …
Matched Iupac: … 3-[(4-amino-6-methylpyridin-3-yl)methyl]-5-(2-{[(hydrogen phosphonatooxy)(hydroxy)phosphoryl]oxy}ethyl ... )-4-methyl-1,3-thiazol-3-ium …
PF-05089771
PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee).
Investigational
Matched Iupac: … 4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzene-1-sulfonamide …
2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine
Experimental
Matched Name: … 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
Matched Iupac: … ({[(2S)-1-(2,6-diamino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate …
Displaying drugs 9451 - 9475 of 10915 in total