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Displaying drugs 926 - 950 of 980 in total
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … Ouabain anhydrous
Matched Description: … gratus and other plants of the Apocynaceae; used like digitalis. ... A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus …
Investigational
Matched Synonyms: … Des-(2-7)-human insulin-like growth factor ii fusion protein with glycyl-l-alanyl-l-prolyl-human lysosomal …
Experimental
Matched Name: … Ethyl Dimethyl Ammonio Propane Sulfonate
Matched Iupac: … 3-(ethyldimethylazaniumyl)propane-1-sulfonate
An antineoplastic compound which also has antimetabolite action. The drug is used in the therapy of acute leukemia.
Approved
Matched Synonyms: … Thioguanine anhydrous ... Thioguanine, anhydrous
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Experimental
Matched Name: … D-Gluco-2,5-Anhydro-1-Deoxy-1-Phosphonohexitol-6-Phosphate …
Investigational
Matched Synonyms: … Sulindac sulfone
Experimental
Matched Synonyms: … para-toluene sulfonate
Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.[L8384,L8387,L8390] Lisinopril and captopril are the only ACEIs that are not prodrugs. It functions by inhibition of angiotensin converting enzyme as well as the renin angiotensin aldosterone system.[A184781,A184808,A184817] ACEIs are commonly used as a...
Approved
Investigational
Matched Synonyms: … Lisinopril anhydrous
Matched Description: … [L8384,L8387,L8390] Lisinopril and [captopril] are the only ACEIs that are not prodrugs. ... Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and
Matched Mixtures name: … Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide ... Lisinopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... ACE Inhibitors and Calcium Channel Blockers ... Amino Acids, Peptides, and Proteins ... lisinopril and diuretics ... lisinopril and amlodipine …
Experimental
Matched Name: … [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE …
Pinometostat has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
Investigational
Matched Synonyms: … PINOMETOSTAT ANHYDROUS
Matched Description: … studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … modified autologous cell therapy intended for the stable provision of functional human iduronate-2-sulfatase
Matched Description: … autologous stem cells transduced _ex vivo_ with a lentiviral vector encoding the human iduronate-2-sulfatase
Approved
Experimental
Matched Synonyms: … glycerol α-p-chlorophenyl ether …
Matched Categories: … Glycols ... Propylene Glycols
A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Synonyms: … Indinavir anhydrous
Matched Description: … A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. …
Matched Salts name: … Indinavir sulfate ... Indinavir sulfate ethanolate …
Cyclosporine is a calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and treat various inflammatory and autoimmune conditions. It is isolated from the fungus Beauveria nivea. Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products...
Approved
Investigational
Vet approved
Matched Description: … treat various inflammatory and autoimmune conditions. ... calcineurin inhibitor known for its immunomodulatory properties that prevent organ transplant rejection and ... [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Cyclosporine/Chondroitin Sulfate PF …
Bosentan is a dual endothelin receptor antagonist marketed under the trade name Tracleer by Actelion Pharmaceuticals. Bosentan is used to treat pulmonary hypertension by blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and lead to high blood pressure.
Approved
Investigational
Matched Synonyms: … bosentan anhydrous
Matched Description: … blocking the action of endothelin molecules that would otherwise promote narrowing of the blood vessels and
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Experimental
Matched Name: … 2-{[N-(2-ACETYL-5-CHLORO-4-FLUOROPHENYL)GLYCYL]AMINO}BENZOIC ACID …
Experimental
Matched Name: … 2,6-Anhydro-3-Deoxy-D-Erythro-Hex-2-Enonic Acid …
Experimental
Matched Synonyms: … (6R)-5-Acetamido-6-[(1R,2R)-3-amino-1,2-dihydroxypropyl]-2,6-anhydro-3,5-dideoxy-L-threo-hex-2-enonic …
Investigational
Matched Synonyms: … Glycyl-l-prolyl-human cancer/testis antigen 1 (autoimmunogenic cancer/testis antigen ny-eso-1, l antigen …
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Matched Synonyms: … glycolic acid [o-(2,6-dichloroanilino)phenyl]acetate ester …
Matched Description: … Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and ... analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. ... synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and
Matched Categories: … Acetic Acid Derivatives and Related Substances ... Antiinflammatory and Antirheumatic Products ... Topical Products for Joint and Muscular Pain ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Synonyms: … Pyridoxal phosphate anhydrous
Matched Mixtures name: … Levomefolate Calcium, Pyridoxal 5-phosphate, Methylcobalamin and Schizochytrium DHA Oil …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body's vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
Approved
Nutraceutical
Matched Synonyms: … Calcifediol anhydrous
Matched Description: … It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients ... It is produced in the liver and is the best indicator of the body's vitamin D stores. …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Vitamin D and Analogues ... Sex Hormones and Insulins …
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … Gatifloxacin anhydrous
Matched Description: … It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Miglitol inhibits the breakdown complex carbohydrates into glucose. It is primarily used in diabetes mellitus type 2 for establishing greater glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and polysaccharides) into monosaccharides which can be absorbed by the body. Miglitol should be taken at the start...
Approved
Matched International brands: … Glycet
Matched Description: … amount of poly and oligosaccharides in the diet. ... glycemic control by preventing the digestion of carbohydrates (such as disaccharides, oligosaccharides, and ... Miglitol should be taken at the start of a meal for maximal effect and the effect will depend on the …
Matched Categories: … Alimentary Tract and Metabolism …
Experimental
Matched Name: … 2-(cycloheptylmethyl)-1,1-dioxido-1-benzothiophen-6-yl sulfamate
Matched Iupac: … 2-(cycloheptylmethyl)-1,1-dioxo-1lambda6-benzothiophen-6-yl sulfamate
Displaying drugs 926 - 950 of 980 in total