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Displaying drugs 951 - 975 of 1197 in total

Risedronic acid

Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Investigational
Matched Description: … acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Mixtures name: … FEMARİS PLUS 150 MG/5600 IU FİLM KAPLI TABLET, 3 ADET …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Drugs Affecting Bone Structure and Mineralization ... risedronic acid and colecalciferol ... risedronic acid and calcium, sequential ... risedronic acid, calcium and colecalciferol, sequential …
Matched Products: … ACTEDAY 5 MG FİLM TABLET, 28 ADET ... BONEPLUS 5 MG FİLM TABLET, 28 ADET ... INDRONATE FILM-COATED TABLET 35 MG …

Ebastine

Ebastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Approved
Investigational
Matched Products: … Kestine 10mg film-coated tablets ... Kestine 20mg film-coated tablets ... KESTINE FILM-COATED TABLET 20MG …

Bacampicillin

Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. During absorption from the gastrointestinal tract, bacampicillin is hydrolyzed by esterases present in the intestinal wall. It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of...
Approved
Investigational
Matched Description: … Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. ... It is used to cure infection of upper and lower respiratory tract; skin and soft tissue; urinary tract ... and acute uncomplicated gonococcal urethritis etc. …
Matched Products: … İEBAK 400 MG FILM TABLET 10 ADET ... İEBAK 800 MG FILM TABLET 10 ADET ... SANOSİLİN 400 MG FİLM TABLET, 10 TABLET …

Roflumilast

Roflumilast is a highly selective phosphodiesterase-4 (PDE4) inhibitor. PDE4 is a major cyclic-3',5′-adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme expressed on nearly all immune and pro-inflammatory cells, in addition to structural cells like those of the smooth muscle or epithelium. The resultant increase in intracellular cAMP induced by roflumilast's inhibition of PDE4...
Approved
Matched Description: … adenosinemonophosphate (cyclic AMP, cAMP)-metabolizing enzyme [L37564] expressed on nearly all immune and ... [L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018. ... The cream formulation was first approved by the FDA in July 2022 [L42580] and by Health Canada in April …
Matched Products: … DAXAS 500 MCG FILM-COATED TABLETS ... DAXAS 500 MCG FILM TABLET, 30 ADET ... DAXAS 500 MCG FILM TABLET, 90 ADET …

Ribavirin

Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. It is primarily indicated for use in treating hepatitis C and viral hemorrhagic fevers. HCV is a single-stranded RNA virus that is categorized...
Approved
Matched Description: … Producing a broad-spectrum activity against several RNA and DNA viruses, Ribavirin is a synthetic guanosine ... nucleoside and antiviral agent that interferes with the synthesis of viral mRNA. ... The dual therapy was administered for 48 weeks in patients with genotype 1, 4, 5, and 6, and 24 weeks …
Matched Mixtures name: … Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules) …
Matched Categories: … Nucleosides and Nucleotides ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Products: … Copegus film coated tablet 200mg ... VIRON 400 MG FİLM KAPLI TABLET, 56 ADET ... VİRANİS 200 MG FİLM TABLET, 70 ADET …

Rosuvastatin

Rosuvastatin, also known as the brand name product Crestor, is a lipid-lowering drug that belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage elevated lipid levels by inhibiting the endogenous production of cholesterol in the liver. More specifically, statin medications...
Approved
Matched Description: … belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and ... of metabolic reactions involved in the production of several compounds involved in lipid metabolism and ... including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and …
Matched Mixtures name: … Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe ... Rosuvastatin and Ezetimibe …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... rosuvastatin and valsartan ... Gynecological Antiinfectives and Antiseptics ... gemigliptin and rosuvastatin …
Matched Products: … Mar-rosuvastatin ... RONAP 20 MG FILM TABLET , FILM TABLET, 28 ADET ... RONAP 20 MG FILM TABLET , FILM TABLET, 84 ADET …

Sultamicillin

Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated ... Pneumonia and Chronic Obstructive Pulmonary Disease (COPD). …
Matched Products: … AMPISID 750 MG FILM TABLET, 10 ADET ... AMPİSİD 375 MG FİLM TABLET, 10 ADET ... DEVASID 375 MG FILM TABLET, 20 ADET …

Metformin

Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.[L12207,A176173] Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabetes without causing hypoglycemia. It is commonly described as an "insulin sensitizer", leading to a decrease in insulin...
Approved
Matched Description: … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management ... It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and ... [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval …
Matched Mixtures name: … Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride ... Glipizide and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... metformin and sulfonylureas ... metformin and gemigliptin ... metformin and linagliptin …
Matched Products: … Mar-metformin ... METVEL 850 MG FILM KAPLI TABLET, 50 FILM KAPLI TABLET ... METVEL 850 MG FILM KAPLI TABLET, 100 FILM KAPLI TABLET …

Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha sterol demethylase...
Approved
Matched Description: … These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. …
Matched Categories: … Triazole and tetrazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Matched Products: … VFEND FILM-COATED TABLET 50 mg ... VFEND FILM-COATED TABLET 200 mg ... VFEND 50 MG FILM TABLET, 14 ADET …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune ... European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Olumiant 2mg Film-Coated Tablets ... Olumiant 4mg Film-Coated Tablets ... OLUMIANT FILM-COATED TABLET 2MG …

Finerenone

Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Description: … [A236544] Spironolactone has low selectivity and affinity for the receptor; it dissociates quickly and ... decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and ... [A236544] Eplerenone is more selective and has longer lasting effects. …
Matched Products: … KERENDIA FILM-COATED TABLET 10MG ... KERENDIA FILM-COATED TABLET 20MG ... KERENDİA 10 MG FİLM KAPLI TABLET, 98 ADET …

Apremilast

Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases. It belongs to the same drug class as Roflumilast and Crisaborole.[A181244,L7495] Initially approved in 2014, it is marketed by Celgene. In July 2019, apremilast was granted...
Approved
Investigational
Matched Description: … It belongs to the same drug class as [Roflumilast] and [Crisaborole]. ... associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and …
Matched Mixtures name: … Mar-apremilast ... Mar-apremilast ... Mar-apremilast …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Mar-apremilast ... OTEZLA FILM-COATED TABLETS 30 MG ... OTEZLA FILM-COATED TABLETS 20 MG …

Abemaciclib

Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA granted approval of abemaciclib treatment under the market name Verzenio for...
Approved
Investigational
Matched Description: … Abemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6 ... Abemaciclib has been used in trials studying the treatment of melanoma, lymphoma, neoplasm, solid tumor ... , and glioblastoma. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Yulareb 50mg film-coated tablets ... Yulareb 150mg film-coated tablets ... VERZENIO FILM-COATED TABLET 50MG …

Brigatinib

Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and epidermal growth factor receptor (EGFR). It presents selectivity against the mutant forms of EGFR compared to the wild-type. It also exhibits selectivity against 9 different Crizotinib-resistant mutants of the EML4-ALK fusion gene, which is a...
Approved
Investigational
Matched Description: … Brigatinib, originally named AP26113, is a reversible dual inhibitor of anaplastic lymphoma kinase (ALK) and ... Brigatinib was developed by Ariad Pharmaceuticals, a subsidiary of Takeda Pharmaceutical Company Limited, and …
Matched Mixtures name: … ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 21 ADET 180 MG ... ALUNBRİG 90 MG VE 180 MG FİLM KAPLI TABLET TEDAVİYE BAŞLANGIÇ PAKETİ, 7 ADET 90 MG VE 23 ADET 180 MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ALUNBRIG FILM-COATED TABLET 30mg ... ALUNBRIG FILM-COATED TABLET 90mg ... ALUNBRIG FILM-COATED TABLET 180mg …

Memantine

Initially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). It is different from many other Alzheimer's Disease medications, as it works by a different mechanism than the cholinesterase enzyme inhibitors normally employed in the management of Alzheimer's...
Approved
Investigational
Matched Description: … blocks the effects of glutamate, a neurotransmitter in the brain that leads to neuronal excitability and ... doubling every 20 years, the prevalence of Alzheimer's Disease is predicted to reach 66 million by 2030 and …
Matched Mixtures name: … Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release ... Memantine and Donepezil Hydrochlorides Extended-release …
Matched Categories: … donepezil and memantine ... donepezil, memantine and Ginkgo folium …
Matched Products: … MENTAX 10 MG FILM TABLET,FILM TABLET, 100 ADET ... AXURA 5/10/15/20MG FILM ST ... ALMENTA 15MG FILM TABLET, 28 ADET …

Vericiguat

Vericiguat is a direct stimulator of soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and hospitalizations. A key component of the NO-sGC-cGMP signaling pathway that helps to regulate the cardiovascular system, sGC enzymes are intracellular enzymes found in vascular smooth muscle cells (amongst...
Approved
Investigational
Matched Description: … soluble guanylate cyclase (sGC) used in the management of systolic heart failure to reduce mortality and ... messenger, activating a number of downstream signaling cascades that elicit a broad variety of effects, and ... A227458] As a direct stimulator of sGC, vericiguat mitigates the need for a functional NO-sGC-cGMP axis and …
Matched Products: … VERQUVO FILM-COATED TABLET 2.5MG ... VERQUVO FILM-COATED TABLET 10MG ... VERQUVO FILM-COATED TABLET 5MG …

Trimetazidine

Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response...
Approved
Investigational
Matched Description: … to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. ... [A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response …
Matched Products: … SITOREL MR 35 MG DEĞIŞTIRILMIŞ SALIMLI FILM TABLET,FILM TABLET, 60 ADET ... SITOREL 20 MG FILM TABLET, 60 ADET ... VASOFIX 20 MG FILM TABLET, 60 ADET …

Sevelamer

Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Approved
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Matched Products: … SEVYAR 800 MG FILM KAPLI TABLET , 90 FILM KAPLI TABLET ... SEVELA FILM COATED TABLET 800MG ... RENADIN 800 MG FILM TABLET, 180 ADET …

Desogestrel

Desogestrel, a prodrug, is a third generation progestogen and hence, a member of the gonane family which was largely used in Europe before being approved in the US and Canada. It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent in nortestosterone can enhance the biological...
Approved
Matched Description: … Desogestrel, a prodrug, is a third generation progestogen[A176315] and hence, a member of the gonane ... family which was largely used in Europe before being approved in the US and Canada. ... [A176339] It was firstly generated from a study that showed that 11-beta and 11-alkylidene substituent …
Matched Mixtures name: … Solia ... Marfem 21 ... Marfem 28 …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... Genito Urinary System and Sex Hormones ... desogestrel and estrogen ... desogestrel and ethinylestradiol ... desogestrel and ethinylestradiol …
Matched Products: … Desirett 75mcg film-coated tablet ... Azalia 0.075 mg film-coated tablet ... DESIRETT 75 MCG FILM KAPLI TABLET ,28 ADET …

Risperidone

Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and mental health conditions including schizophrenia and bipolar disorder. It is one of the most widely used SGAs. Paliperidone, another commonly used SGA, is the primary active metabolite of risperidone (i.e. 9-hydroxyrisperidone). Schizophrenia and...
Approved
Investigational
Matched Description: … Risperidone is a second-generation antipsychotic (SGA) medication used in the treatment of a number of mood and ... mental health conditions including schizophrenia and bipolar disorder. ... D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical …
Matched Products: … Mar-risperidone ... RISPERIDON - CT 0.5MG FILM ... WELRIS 1 MG FİLM TABLET, 30 ADET …

Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Description: … that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and …
Matched Mixtures name: … Glyxambi Film-Coated Tablets 25mg/5mg ... Glyxambi Film-Coated Tablets 10mg/5mg ... GLYXAMBI FILM-COATED TABLETS 25 MG/5 MG …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and linagliptin ... linagliptin and empagliflozin ... metformin, linagliptin and empagliflozin ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRAJENTA 5MG FILM-COATED TABLETS ... SNOXX 5 MG FİLM KAPLI TABLET ... TRAJENTA 5 MG FILM KAPLI TABLET …

Dacomitinib

Dacomitinib, designed as (2E)-N-16-4-(piperidin-1-yl) but-2-enamide, is an oral highly selective quinazalone part of the second-generation tyrosine kinase inhibitors which are characterized by the irreversible binding at the ATP domain of the epidermal growth factor receptor family kinase domains. Dacomitinib was developed by Pfizer Inc and approved by the FDA on...
Approved
Investigational
Matched Description: … [A40009] Dacomitinib was developed by Pfizer Inc and approved by the FDA on September 27, 2018. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Vizimpro 30 mg Film-Coated Tablets ... Vizimpro 15 mg Film-Coated Tablets ... VIZIMPRO FILM-COATED TABLET 15MG …

Roxadustat

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels. Roxadustat was first approved...
Approved
Investigational
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs …
Matched Products: … EVRENZO 20 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 50 MG FİLM KAPLI TABLET, 12 ADET ... EVRENZO 70 MG FİLM KAPLI TABLET, 12 ADET …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Products: … LEDASON 60 MG FİLM KAPLI TABLET, 30 ADET ... LEDASON 120 MG FİLM KAPLI TABLET, 30 ADET ... LUİGON 20 MG FİLM KAPLI TABLET, 30 ADET …

Mirabegron

Mirabegron is a sympathomimetic beta-3 adrenergic receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and incontinence. It is unique amongst overactive bladder treatment options in that, unlike other treatments such as solifenacin and darifenacin, it lacks significant antimuscarinic activity, which is...
Approved
Matched Description: … receptor agonist used to relax the smooth muscle of the bladder in the treatment of urinary frequency and ... amongst overactive bladder treatment options in that, unlike other treatments such as [solifenacin] and ... antimuscarinic activity,[A232553] which is responsible both for the therapeutic effects of these medications and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 10 TABLET ... BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 100 TABLET ... BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 50 TABLET …
Displaying drugs 951 - 975 of 1197 in total