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Displaying drugs 951 - 975 of 1094 in total

Dapsone

A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-aminophenyl sulfone ... p-aminophenyl sulfone ... bis(4-aminophenyl)sulfone …
Matched Description: … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine …

Somatrogon

Somatrogon is a long-acting recombinant human growth hormone. Growth hormone is a peptide hormone secreted by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and adolescence and regulating metabolic function in adulthood. Recombinant growth hormone therapy for growth hormone deficiency and other conditions has...
Approved
Matched Synonyms: … .)-(118-145)-PEPTIDE (1-28) WITH HUMAN SOMATOTROPIN (GROWTH HORMONE, GH) (29-219) AND TWO TANDEM COPIES …
Matched Description: … adolescence and regulating metabolic function in adulthood. ... of somatrogon and allows its once-weekly dosing. ... by the pituitary gland that plays a crucial role in promoting longitudinal growth during childhood and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Somatropin and Somatropin Agonists …

[(2R,3S,4R,5R)-5-(4-acetonyl-3-carbamoyl-pyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate

Experimental
Matched Synonyms: … Nicotinamide adenine dinucleotide acetone adduct …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Salts name: … Rabeprazole sodium …
Matched Categories: … Acetates ... Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and metronidazole …
Matched Products: … Rabeprazole sodium ... Rabeprazole Sodium ... Rabeprazole Sodium DR …

Ciprocinonide

Approved
Investigational
Matched Synonyms: … 6α,9-Difluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, ... .,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, 21-cyclopropanecarboxylate …

Methylphenidate

Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Synonyms: … methyl phenyl(piperidin-2-yl)acetate ... methyl α-phenyl-α-(2-piperidyl)acetate …
Matched Iupac: … methyl 2-phenyl-2-(piperidin-2-yl)acetate …
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Categories: … Medications that reduce magnesium levels ... Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …

Ertugliflozin

Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes mellitus. It works to block glucose reabsorption from the glomerulus. Ertugliflozin was first approved by the FDA in December 2017.[A261951, L1132] It was also approved by the European Commission in March 2018.
Approved
Investigational
Matched Synonyms: … 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose ... β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)- …
Matched Description: … Ertugliflozin is a sodium-dependent glucose cotransporter-2 (SGLT2) inhibitor used to treat type II diabetes …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and ertugliflozin ... sitagliptin and ertugliflozin ... Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Salts name: … Terlipressin acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TERLIPRESSINA ACETATO EVER PHARMA …

Caspofungin

Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Description: … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan ... Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug …
Matched Salts name: … Caspofungin acetate …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Caspofungin Acetate ... Caspofungin acetate ... Caspofungin Acetate for Injection …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Salts name: … Fucidate sodium …
Matched Products: … FUSIDATO DI SODIO ISDIN ... Axcel Sodium Fusidate 250 Tablet ... VAXCEL SODIUM FUSIDATE-500MG INJECTION …

Fluvastatin

Fluvastatin is an antilipemic agent that competitively inhibits hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...
Approved
Matched Description: … levels and prevent cardiovascular disease. ... Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin. ... Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol …
Matched Salts name: … Fluvastatin sodium …
Matched Products: … Fluvastatin Sodium ... Fluvastatin Sodium ER …

Dextrorphan

Experimental
Matched Synonyms: … Dextro-dromoran …

Pantothenyl-Aminoethanol-Acetate Pivalic Acid

Experimental
Matched Name: … Pantothenyl-Aminoethanol-Acetate Pivalic Acid …

Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Description: … bacilli and gram-negative bacilli. ... used off-label in the treatment of toxoplasmosis, malaria, and babesiosis. ... [A190621] Interestingly, clindamycin appears to carry some activity against protozoans, and has been …
Matched Mixtures name: … Clindamycin 1% / Sodium Sulfacetamide Monohydrate 5% / Tretinoin 0.025% ... Clindamycin Phosphate and Tretinion ... Clindamycin and Benzoyl Peroxide …
Matched Categories: … Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Macrolides, Lincosamides and Streptogramins …
Matched Products: … Clindamycin in 5 Percent Dextrose ... Clindamycin in 5 percent Dextrose ... Clindamycin Injection In 5% Dextrose …

Methyl Methylsulfinylmethyl Sulfide

Experimental
Matched Name: … Methyl Methylsulfinylmethyl Sulfide …

1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine

1-(2-Phenylethyl)-4-phenyl-4-acetoxypiperidine (PEPAP) is a synthetic analogue of meperidine. It is sold as a "synthetic heroin."
Experimental
Illicit
Matched Synonyms: … 1-Phenethyl-4-phenyl-4-piperidinol acetate (ester) …
Matched Iupac: … 4-phenyl-1-(2-phenylethyl)piperidin-4-yl acetate …

Obeldesivir

Investigational
Matched Synonyms: … 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D -altrononitrile 6-(2-methylpropanoate) ... D-Altrononitrile, 2-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-, 6-(2-methylpropanoate) …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

cis-tetracosenoyl sulfatide

Experimental
Matched Synonyms: … C24:1 Sulfatide …
Matched Name: … cis-tetracosenoyl sulfatide …

Ethyl biscoumacetate

Ethyl biscoumacetate is a courmarin that is used as an anticoagulant. It has actions similar to those of Warfarin. (From Martindale, The Extra Pharmacopoeia, 30th ed, p226)
Withdrawn
Matched Synonyms: … Ethyl bis(4-hydroxy-2-oxo-2h-1-benzopyran-3-yl)acetate …
Matched Iupac: … ethyl 2,2-bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate …
Matched Categories: … Blood and Blood Forming Organs …

Desmopressin

Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the...
Approved
Matched Description: … The active ingredient in most formulations is desmopressin acetate. ... solution, intravenous solution, oral tablet and oral lyophilisate [A31662]. ... 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and …
Matched Salts name: … Desmopressin acetate anhydrous ... Desmopressin acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Desmopressin Acetate ... Desmopressin acetate …

Epinephrine

Epinephrine, also known as adrenaline, is a hormone and neurotransmitter and produced by the adrenal glands that can also be used as a drug due to its various important functions. Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been...
Approved
Vet approved
Matched Description: … Epinephrine, also known as _adrenaline_, is a hormone and neurotransmitter and produced by the adrenal ... other allergens, and to prolong the action of infiltration anesthetics [F2136]. ... Many new products/biosimilars and dosage routes have been approved under various names over the last …
Matched Mixtures name: … Lidocaine Hydrochloride and Epinephrine ... Lidocaine Hydrochloride and Epinephrine ... Lidocaine Hydrochloride and Epinephrine …
Matched Salts name: … Epinephrine acetate …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Epinephrine and similars ... Alpha-and Beta-adrenergic Agonists ... Antiglaucoma Preparations and Miotics ... epinephrine and other drugs for obstructive airway diseases …
Matched Products: … Epinephrine Chloride Solution …

L-methionine sulfone

Experimental
Matched Synonyms: … Methionine sulfone …
Matched Name: … L-methionine sulfone …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sennosides

Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given...
Experimental
Matched Description: … also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and ... It typically begins working in minutes when given by rectum and within twelve hours when given by mouth …
Matched Mixtures name: … Senna and Docusate Sodium ... Senna and Docusate Sodium ... Sennosides and Docusate Sodium …
Matched Salts name: … Sennosides A and B …
Matched Categories: … Alimentary Tract and Metabolism ... Herbs and Natural Products …
Matched Products: … Calcium Sennosides 20% ... Calcium Sennosides 60% …

TK-112690

Investigational
Matched Synonyms: … O2,2'-anhydro-5-methyluridine …

Sibutramine

Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the...
Approved
Illicit
Investigational
Withdrawn
Matched Description: … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide ... increases the risk of heart attack and stroke in patients with a history of heart disease. ... In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug …
Matched Categories: … Alimentary Tract and Metabolism ... Serotonin and Noradrenaline Reuptake Inhibitors ... Norepinephrine, Serotonin, and Dopamine Reuptake Inhibitor Anorectic …
Matched Products: … SUBUTRAMINA CLORHIDRATO MONOHIDRATO 10 MG …
Displaying drugs 951 - 975 of 1094 in total