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Displaying drugs 9826 - 9850 of 10272 in total

Zinpentraxin alfa

Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis).
Investigational
Matched Synonyms: … rhPTX-2 ... Recombinant human pentraxin-2 …
Matched Description: … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein. ... It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With …

Ontamalimab

Ontamalimab is under investigation in clinical trial NCT03627091 (Efficacy and Safety Study of SHP647 as Maintenance Treatment in Participants With Moderate to Severe Crohn's Disease (CARMEN CD 307)).
Investigational

Merestinib

Merestinib has been used in trials studying the treatment of Cancer, Solid Tumor, Advanced cancer, ColoRectal Cancer, and Metastatic Cancer, among others.
Investigational
Matched Iupac: … N-(3-fluoro-4-{[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy}phenyl)-1-(4-fluorophenyl)-6-methyl- ... 2-oxo-1,2-dihydropyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Sitravatinib

Sitravatinib is under investigation in clinical trial NCT03680521 (Neoadjuvant Sitravatinib in Combination With Nivolumab in Patients With Clear Cell Renal Cell Carcinoma).
Investigational
Matched Iupac: … N'1-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl ... )-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide …

RO-6870810

RO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Investigational
Matched Iupac: … (6),4,7,10,12-pentaen-9-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide ... 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2 …

Elenbecestat

Elenbecestat is under investigation in clinical trial NCT02956486 (A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Subjects With Early Alzheimer's Disease).
Investigational
Matched Iupac: … N-{3-[(4aS,5R,7aS)-2-amino-5-methyl-4H,4aH,5H,7H,7aH-furo[3,4-d][1,3]thiazin-7a-yl]-4-fluorophenyl}-5 ... -(difluoromethyl)pyrazine-2-carboxamide …

8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE

Experimental
Matched Iupac: … 8-[(6-bromo-2H-1,3-benzodioxol-5-yl)sulfanyl]-9-{3-[(propan-2-yl)amino]propyl}-9H-purin-6-amine …

Efaproxiral

Investigational
Matched Iupac: … 2-(4-{[(3,5-dimethylphenyl)carbamoyl]methyl}phenoxy)-2-methylpropanoic acid …

D-Tyrosine

A non-essential amino acid. In animals it is synthesized from PHENYLALANINE. It is also the precursor of EPINEPHRINE; THYROID HORMONES; and melanin.
Experimental
Matched Synonyms: … (R)-2-Amino-3-(p-hydroxyphenyl)propionic acid …
Matched Iupac: … (2R)-2-amino-3-(4-hydroxyphenyl)propanoic acid …

L-erythro-7,8-dihydrobiopterin

7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.
Experimental
Matched Iupac: … 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-1,4,7,8-tetrahydropteridin-4-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Bromopyruvate

Investigational
Matched Synonyms: … 3-bromo-2-oxopropanoic acid …
Matched Iupac: … 3-bromo-2-oxopropanoic acid …

BGT-DTDS

BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) encoding the human SLC6A3 gene. It is under investigation for the treatment of dopamine transporter deficiency syndrome (DTDS).
Investigational
Matched Synonyms: … Adeno-associated viral vector serotype 2 containing the human SLC6A3 gene …
Matched Description: … BGT-DTDS is an investigational gene therapy comprising an adeno-associated viral vector type 2 (AAV2) …

Batoclimab

Batoclimab is under investigation in clinical trial NCT04428255 (A Clinical Study on the Efficacy and Safety of HBM9161 in Patients With ITP).
Investigational

Efavaleukin alfa

Efavaleukin alfa is a fusion protein consisting of interleukin mutein fused to the C-terminus of an immunoglobulin G Fc domain by way of a G4S linker. It is under investigation in clinical trial NCT03422627 (Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease).
Investigational
Matched Synonyms: … Fc il-2 mutein fusion protein (amg-592) ... domain-containing fragment) fusion protein with peptide (synthetic linker) fusion protein with interleukin 2 …

Domvanalimab

Domvanalimab is under investigation in clinical trial NCT05502237 (Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-small Cell Lung Cancer).
Investigational

5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine

5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine is a solid. This compound belongs to the benzene and substituted derivatives. These are aromatic compounds containing at least one benzene ring. This drug targets the protein methionine aminopeptidase.
Experimental
Matched Name: … 5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine …
Matched Iupac: … 4-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-4,5-dihydro-3H-pyrazole-3,5-diimine …
Matched Description: … 5-imino-4-(3-trifluoromethyl-phenylazo)-5H-pyrazol-3-ylamine is a solid. …

Panax ginseng whole

Panax ginseng whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental

Otenabant

Otenabant has been investigated for the treatment of Obesity.
Investigational
Matched Iupac: … 1-[8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl]-4-(ethylamino)piperidine-4-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Lodenafil carbonate

Lodenafil carbonate has been used in trials studying the treatment of Coronaropathy and Erectile Dysfunction.
Investigational
Matched Iupac: … bis{2-[4-(4-ethoxy-3-{1-methyl-7-oxo-3-propyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-5-yl}benzenesulfonyl) …

3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER

Experimental
Matched Name: … 3-(HYDROXY-PHENYL-PHOSPHINOYLOXY)-8-METHYL-8-AZA-BICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID METHYL ESTER …
Matched Iupac: … {[(1R,2R,3S,5S)-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]oxy}(phenyl)phosphinic acid …

Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate

Experimental
Matched Name: … Open Form of 2'-Deoxy-Ribofuranose-5'-Phosphate …

(2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE

Experimental
Matched Name: … (2-AMINO-1,3-OXAZOL-5-YL)-(3-BROMOPHENYL)METHANONE …
Matched Iupac: … 5-(3-bromobenzoyl)-1,3-oxazol-2-amine …

Hydroxy-Phenyl-Acetic Acid 8-Methyl-8-Aza-Bicyclo[3.2.1]Oct-3-Yl Ester

Experimental
Matched Iupac: … (1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl (2R)-2-hydroxy-2-phenylacetate …

Zorubicin

Zorubicin is a drug of the anthracycline class - a class of medications that have historically demonstrated effective chemotherapy for a variety of cancer types.
Experimental
Matched Iupac: … N'-{1-[(2S,4S)-4-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-2,5,12-trihydroxy-7-methoxy ... -6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl]ethylidene}benzohydrazide …

3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid

Experimental
Matched Name: … 3,3-Dichloro-2-Phosphonomethyl-Acrylic Acid …
Matched Iupac: … 3,3-dichloro-2-(phosphonomethyl)prop-2-enoic acid …
Displaying drugs 9826 - 9850 of 10272 in total